Message archive
Sven Kuspiel successfully defends his doctoral thesis
Today, our PhD student Sven Kuspiel successfully defended his doctoral thesis, in which he had analysed with electrophysiological methods the interaction of a new associated protein with Acid-Sensing…
What ist he role of acid-sensing ion channels in tumour cells??
Acid-sensing ion channels (ASICs) are proton-gated Na+-channels, which are normally expressed in neurons. However, also many tumour cells express ASICs. Because tumour cells thrive in an acidic…
High concentrations of the pineal hormone melatonin have profound effects on neuronal excitability
Melatonin is well known as “sleeping hormone”. In the USA and Canada, it is also sold as an over-the-counter dietary supplement and strong antioxidative effects and positive effects on diverse…
Jan Clusmann receives the Best thesis Award of the German Physiological Society
Today, our former MD student, Jan Clusmann (on the left), received the Dissertation Award of the German Physiological Society (DPG) for his medical thesis. He received the award at the annual meeting…
Functional characterisation of Acid-Sensing Ion Channels in Glioblastoma stem cell lines
Typically, the micro-environment of a tumour has a slightly acidic pH. It it therefore important to characterize acid sensors, like Acid-sensing ion channels (ASICs), in tumor cells. In our most…
Functional characterisation of an important heteromeric Acid-Sensing Ion Channels of the PNS
Acid-sensing ion channels (ASICs) are proton-gated ion channels that are also expressed in the peripheral nervous system where they detect painful acidosis. ASICs assemble as homo- or heterotrimers.…
Modulation of Acid-Sensing Ion Channels by tannic acid and green tea
Phytochemicals represent a large pool of substances with the potential to modulate diverse proteins, for example ion channels. In our recent study, which has been published in the journal ACS Chemical…
Our former scientist Elinor Cleuvers successfully finished her MD thesis
Today our MD student Elinor Cleuvers successfully passed the oral examination at the end of her thesis. Part of the results of her doctoral thesis entitled „Interaction of the opioid neuropeptid Big…
Das Institut für Physiologie trauert um Helmut Kammermeier
Am 21.02.2023 verstarb Helmut Kammermeier, von 1971-1997 Professor am Institut für Physiologie. Bereits 1966 kam H. Kammermeier mit dem Gründungsdirektor des Instituts, Eckehard Gerlach, aus Freiburg…
Jan Clusmann successfully finished his MD thesis with highest honors.
Today our MD student Jan Clusmann successfully passed the oral examination at the end of his thesis with summa cum laude. The results of his doctoral thesis entitled „Acid-sensing ion channel 1a…