In view of the COVID-19 pandemic, a central registry was established at the Uniklinik RWTH Aachen for autopsies of COVID-19 deceased persons (DeRegCOVID). This was done with the support of the Federal Association of German Pathologists e.V. (BDP) and the German Society of Pathology (DGP). (DeRegCOVID).
This initiative is strongly welcomed and supported by the Federal Ministry of Health.
Even today, autopsies continue to play a major role in understanding the pathogenesis of diseases, especially when the disease is caused by a previously unknown pathogen such as SARS-CoV-2.
Despite worldwide efforts to better understand COVID-19 disease, little is known about the pathogenesis of this disease. This applies both to the spread within the human body and the effects on the respective organs and cells. Finally, it is still unclear which predisposing, clinically not manifest pathological changes or underlying diseases, e.g. of the lung tissue, are responsible for severe or lethal courses of the disease.
The autopsies of patients who have died of COVID-19 provide a unique opportunity to help to better understand the pathophysiology and progression of the disease and thus to answer some of the open questions. At best, such findings can improve the therapy of Covid-19 patients currently under treatment.
The aim of the DeRegCOVID Register is to record as many autopsy cases of COVID-19 patients as possible throughout Germany and subsequently serve as a central point of contact for data analysis and research inquiries.
The register is coordinated and managed by the Institute of Pathology of the Uniklinik RWTH Aachen in close cooperation with the Institute of Medical Informatics and the Center for Translational & Clinical Research (CTC-A) of the Uniklinik RWTH Aachen.