The team of Dental Materials and Biomaterials Research (ZWBF) develops tailored biomaterials with tissue engineering techniques. In our team scientists from different disciplines work close together due to the transdisciplinary topic. A focus of the research team is set on 3D tissue engineering. With novel bioprinting techniques tissue replacement made of patients' own cells, embedded in tailored hydrogels can be manufactured as three-dimensional constructs on the centimeter scale. This enables new opportunities for the field of transplantation surgery. Furthermore we realize biomimetic 3D in vitro models using bioprinting techniques. Those 'organ-on-a-chip' called models can be used to explore fundamental scientific questions. In addition, they are of interest for the field of applied research and development as screening platforms for new drugs. Apart from that the team does research on the improvement of biomaterials for long-term implants. Important questions in this context are the osseointegration and the mechanical long-term reliability and lifetime in the clinical use. When exploring novel approaches specific experimental setups as well as tools of numerical simulations will be applied.