Veröffentlichungen von Prof. Vera Jankowski in den letzten 5 Jahren:

  1. Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Triem, S., Klug, M., Schunk, S. J., Schmit, D., Kramann, R., Korbel, C., Ampofo, E., Laschke, M. W., Selejan, S. R., Paschen, A., Herter, T., Schuster, S., Silbernagel, G., Sester, M., Sester, U., Assmann, G., Bals, R., Kostner, G., Jahnen-Dechent, W., Menger, M. D., Rohrer, L., Marz, W., Bohm, M., Jankowski, J., Kopf, M., Latz, E., Niemeyer, B. A., Fliser, D., Laufs, U. & Speer, T. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol 21, 30-41, doi:10.1038/s41590-019-0548-1 (2020).
     
  2. Hermann, J., Noels, H., Theelen, W., Lellig, M., Orth-Alampour, S., Boor, P., Jankowski, V. & Jankowski, J. Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging. Anal Bioanal Chem 412, 1263-1275, doi:10.1007/s00216-019-02296-x (2020).
     
  3. Breitkopf, D. M., Jankowski, V., Ohl, K., Hermann, J., Hermert, D., Tenbrock, K., Liu, X., Martin, I. V., Wang, J., Groll, F., Grone, E., Floege, J., Ostendorf, T., Rauen, T. & Raffetseder, U. The YB-1:Notch-3 axis modulates immune cell responses and organ damage in systemic lupus erythematosus. Kidney Int 97, 289-303, doi:10.1016/j.kint.2019.09.031 (2020).
     
  4. Zhou, Z., Matsumoto, T., Jankowski, V., Pernow, J., Mustafa, S. J., Duncker, D. J. & Merkus, D. Uridine adenosine tetraphosphate and purinergic signaling in cardiovascular system: An update. Pharmacol Res 141, 32-45, doi:10.1016/j.phrs.2018.12.009 (2019).
     
  5. Vollmer, T., Ljungberg, B., Jankowski, V., Jankowski, J., Glorieux, G. & Stegmayr, B. G. An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances. Sci Rep 9, 14525, doi:10.1038/s41598-019-50929-z (2019).
     
  6. van der Made, T. K., Fedecostante, M., Scotcher, D., Rostami-Hodjegan, A., Sastre Torano, J., Middel, I., Koster, A. S., Gerritsen, K. G., Jankowski, V., Jankowski, J., Hoenderop, J. G. J., Masereeuw, R. & Galetin, A. Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease. Mol Pharm 16, 4551-4562, doi:10.1021/acs.molpharmaceut.9b00681 (2019).
     
  7. Sternkopf, M., Thoroe-Boveleth, S., Beck, T., Oleschko, K., Erlenkotter, A., Tschulena, U., Steppan, S., Speer, T., Goettsch, C., Jankowski, V., Jankowski, J., Noels, H. & European Uremic Toxin Work Group, E. A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients. Toxins (Basel) 11, doi:10.3390/toxins11070389 (2019).
     
  8. Schumacher, D., Alampour-Rajabi, S., Ponomariov, V., Curaj, A., Wu, Z., Staudt, M., Rusu, M., Jankowski, V., Marx, N., Jankowski, J., Brandenburg, V., Liehn, E. A. & Schuh, A. Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction. Cardiovasc Pathol 40, 47-54, doi:10.1016/j.carpath.2019.02.001 (2019).
     
  9. Gajjala, P. R., Bruck, H., Noels, H., Heinze, G., Ceccarelli, F., Kribben, A., Saez-Rodriguez, J., Marx, N., Zidek, W., Jankowski, J. & Jankowski, V. Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach. J Mol Med (Berl) 97, 1451-1463, doi:10.1007/s00109-019-01823-8 (2019).
     
  10. Belczacka, I., Pejchinovski, M., Krochmal, M., Magalhaes, P., Frantzi, M., Mullen, W., Vlahou, A., Mischak, H. & Jankowski, V. Urinary Glycopeptide Analysis for the Investigation of Novel Biomarkers. Proteomics Clin Appl 13, e1800111, doi:10.1002/prca.201800111 (2019).
     
  11. Belczacka, I., Latosinska, A., Siwy, J., Metzger, J., Merseburger, A. S., Mischak, H., Vlahou, A., Frantzi, M. & Jankowski, V. Author Correction: Urinary CE-MS peptide marker pattern for detection of solid tumors. Sci Rep 9, 12864, doi:10.1038/s41598-019-49304-9 (2019).
     
  12. Sawant, M., Schwarz, N., Windoffer, R., Magin, T. M., Krieger, J., Mucke, N., Obara, B., Jankowski, V., Jankowski, J., Wally, V., Lettner, T. & Leube, R. E. Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability. J Invest Dermatol 138, 627-636, doi:10.1016/j.jid.2017.10.011 (2018).
     
  13. Noels, H., Theelen, W., Sternkopf, M., Jankowski, V., Moellmann, J., Kraemer, S., Lehrke, M., Marx, N., Martin, L., Marx, G., Jankowski, J., Goetzenich, A. & Stoppe, C. Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery. Sci Rep 8, 11820, doi:10.1038/s41598-018-30235-w (2018).
     
  14. Noels, H., Boor, P., Goettsch, C., Hohl, M., Jahnen-Dechent, W., Jankowski, V., Kindermann, I., Kramann, R., Lehrke, M., Linz, D., Maack, C., Niemeyer, B., Roma, L. P., Schuett, K., Speer, T., Wagenpfeil, S., Werner, C., Zewinger, S., Bohm, M., Marx, N., Floege, J., Fliser, D. & Jankowski, J. The new SFB/TRR219 Research Centre. Eur Heart J 39, 975-977, doi:10.1093/eurheartj/ehy083 (2018).
     
  15. Moellmann, J., Klinkhammer, B. M., Onstein, J., Stohr, R., Jankowski, V., Jankowski, J., Lebherz, C., Tacke, F., Marx, N., Boor, P. & Lehrke, M. Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy. Diabetes 67, 2410-2419, doi:10.2337/db17-1212 (2018).
     
  16. Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. & Jankowski, V. Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease. Neurology 91, e1799-e1808, doi:10.1212/WNL.0000000000006457 (2018).
     
  17. Belczacka, I., Latosinska, A., Siwy, J., Metzger, J., Merseburger, A. S., Mischak, H., Vlahou, A., Frantzi, M. & Jankowski, V. Urinary CE-MS peptide marker pattern for detection of solid tumors. Sci Rep 8, 5227, doi:10.1038/s41598-018-23585-y (2018).
     
  18. Schuett, K., Savvaidis, A., Maxeiner, S., Lysaja, K., Jankowski, V., Schirmer, S. H., Dimkovic, N., Boor, P., Kaesler, N., Dekker, F. W., Floege, J., Marx, N. & Schlieper, G. Clot Structure: A Potent Mortality Risk Factor in Patients on Hemodialysis. J Am Soc Nephrol 28, 1622-1630, doi:10.1681/ASN.2016030336 (2017).
     
  19. Pejchinovski, M., Siwy, J., Metzger, J., Dakna, M., Mischak, H., Klein, J., Jankowski, V., Bae, K. T., Chapman, A. B. & Kistler, A. D. Urine peptidome analysis predicts risk of end-stage renal disease and reveals proteolytic pathways involved in autosomal dominant polycystic kidney disease progression. Nephrol Dial Transplant 32, 487-497, doi:10.1093/ndt/gfw243 (2017).
     
  20. Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W. & Jankowski, J. Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma. Hypertension 70, 412-419, doi:10.1161/HYPERTENSIONAHA.116.08906 (2017).
     
  21. Wang, J., Gibbert, L., Djudjaj, S., Alidousty, C., Rauen, T., Kunter, U., Rembiak, A., Enders, D., Jankowski, V., Braun, G. S., Floege, J., Ostendorf, T. & Raffetseder, U. Therapeutic nuclear shuttling of YB-1 reduces renal damage and fibrosis. Kidney Int 90, 1226-1237, doi:10.1016/j.kint.2016.07.008 (2016).
     
  22. Tetali, S. D., Jankowski, V., Luetzow, K., Kratz, K., Lendlein, A. & Jankowski, J. Adsorption capacity of poly(ether imide) microparticles to uremic toxins. Clin Hemorheol Microcirc 61, 657-665, doi:10.3233/CH-152026 (2016).
     
  23. Latosinska, A., Makridakis, M., Frantzi, M., Borras, D. M., Janssen, B., Mullen, W., Zoidakis, J., Merseburger, A. S., Jankowski, V., Mischak, H. & Vlahou, A. Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings. Sci Rep 6, 25619, doi:10.1038/srep25619 (2016).
     
  24. Chatziharalambous, D., Lygirou, V., Latosinska, A., Stravodimos, K., Vlahou, A., Jankowski, V. & Zoidakis, J. Analytical Performance of ELISA Assays in Urine: One More Bottleneck towards Biomarker Validation and Clinical Implementation. PLoS One 11, e0149471, doi:10.1371/journal.pone.0149471 (2016).
     
  25. Carrick, E., Vanmassenhove, J., Glorieux, G., Metzger, J., Dakna, M., Pejchinovski, M., Jankowski, V., Mansoorian, B., Husi, H., Mullen, W., Mischak, H., Vanholder, R. & Van Biesen, W. Development of a MALDI MS-based platform for early detection of acute kidney injury. Proteomics Clin Appl 10, 732-742, doi:10.1002/prca.201500117 (2016).
     
  26. Bhat, A., Mokou, M., Zoidakis, J., Jankowski, V., Vlahou, A. & Mischak, H. BcCluster: A Bladder Cancer Database at the Molecular Level. Bladder Cancer 2, 65-76, doi:10.3233/BLC-150024 (2016).
     
  27. Salem, S., Jankowski, V., Asare, Y., Liehn, E., Welker, P., Raya-Bermudez, A., Pineda-Martos, C., Rodriguez, M., Munoz-Castaneda, J. R., Bruck, H., Marx, N., Machado, F. B., Staudt, M., Heinze, G., Zidek, W. & Jankowski, J. Identification of the Vasoconstriction-Inhibiting Factor (VIF), a Potent Endogenous Cofactor of Angiotensin II Acting on the Angiotensin II Type 2 Receptor. Circulation 131, 1426-1434, doi:10.1161/CIRCULATIONAHA.114.013168 (2015).
     
  28. Rueth, M., Lemke, H. D., Preisinger, C., Krieter, D., Theelen, W., Gajjala, P., Devine, E., Zidek, W., Jankowski, J. & Jankowski, V. Guanidinylations of albumin decreased binding capacity of hydrophobic metabolites. Acta Physiol (Oxf) 215, 13-23, doi:10.1111/apha.12518 (2015).
     
  29. Pena, M. J., Jankowski, J., Heinze, G., Kohl, M., Heinzel, A., Bakker, S. J., Gansevoort, R. T., Rossing, P., de Zeeuw, D., Heerspink, H. J. & Jankowski, V. Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes. J Hypertens 33, 2123-2132, doi:10.1097/HJH.0000000000000685 (2015).
     
  30. Pejchinovski, M., Klein, J., Ramirez-Torres, A., Bitsika, V., Mermelekas, G., Vlahou, A., Mullen, W., Mischak, H. & Jankowski, V. Comparison of higher energy collisional dissociation and collision-induced dissociation MS/MS sequencing methods for identification of naturally occurring peptides in human urine. Proteomics Clin Appl 9, 531-542, doi:10.1002/prca.201400163 (2015).
     
  31. Pasqualon, T., Pruessmeyer, J., Jankowski, V., Babendreyer, A., Groth, E., Schumacher, J., Koenen, A., Weidenfeld, S., Schwarz, N., Denecke, B., Jahr, H., Dreymueller, D., Jankowski, J. & Ludwig, A. A cytoplasmic C-terminal fragment of Syndecan-1 is generated by sequential proteolysis and antagonizes Syndecan-1 dependent lung tumor cell migration. Oncotarget 6, 31295-31312, doi:10.18632/oncotarget.5174 (2015).
     
  32. Nkuipou-Kenfack, E., Bhat, A., Klein, J., Jankowski, V., Mullen, W., Vlahou, A., Dakna, M., Koeck, T., Schanstra, J. P., Zurbig, P., Rudolph, K. L., Schumacher, B., Pich, A. & Mischak, H. Identification of ageing-associated naturally occurring peptides in human urine. Oncotarget 6, 34106-34117, doi:10.18632/oncotarget.5896 (2015).
     
  33. Latosinska, A., Vougas, K., Makridakis, M., Klein, J., Mullen, W., Abbas, M., Stravodimos, K., Katafigiotis, I., Merseburger, A. S., Zoidakis, J., Mischak, H., Vlahou, A. & Jankowski, V. Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis. PLoS One 10, e0137048, doi:10.1371/journal.pone.0137048 (2015).
     
  34. Lanza, D., Perna, A. F., Oliva, A., Vanholder, R., Pletinck, A., Guastafierro, S., Di Nunzio, A., Vigorito, C., Capasso, G., Jankowski, V., Jankowski, J. & Ingrosso, D. Impact of the uremic milieu on the osteogenic potential of mesenchymal stem cells. PLoS One 10, e0116468, doi:10.1371/journal.pone.0116468 (2015).
     
  35. Gajjala, P. R., Fliser, D., Speer, T., Jankowski, V. & Jankowski, J. Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease. Nephrol Dial Transplant 30, 1814-1824, doi:10.1093/ndt/gfv048 (2015).
     
  36. Bhat, A., Heinzel, A., Mayer, B., Perco, P., Muhlberger, I., Husi, H., Merseburger, A. S., Zoidakis, J., Vlahou, A., Schanstra, J. P., Mischak, H. & Jankowski, V. Protein interactome of muscle invasive bladder cancer. PLoS One 10, e0116404, doi:10.1371/journal.pone.0116404 (2015).