Research Reports
Publications
2013
- Palmowski K, Rix A, Lederle W, Behrendt FF, Mottaghy FM, Gray BD, Pak KY, Palmowski M, and Kiessling F. A low molecular weight zinc(2+)-dipicolylamine-based probe detects apoptosis during tumour treatment better than an annexin V-based probe. Eur Radiol. 2013 Oct 11. doi: 10.1007/s00330-013-3014-8 [Epub ahead of print]
- Kunjachan S, Rychlik B, Storm G, Kiessling F, and Lammers T. Multidrug resistance: Physiological principles and nanomedical solutions. Adv Drug Deliv Rev. 2013 Oct 10. doi: 10.1016/j.addr.2013.09.018 [Epub ahead of print]
- Wu Z, Curaj A, Fokong S, Liehn EA, Weber C, Lammers T, Kiessling F, and van Zandvoort M. Rhodamine-loaded ICAM-targeted Microbubbles for Dual-modality Imaging Under Controlled Shear Stresses. Circ Cardiovasc Imaging. 2013 Sep 13. doi: 10.1161/CIRCIMAGING.113.000805 [Epub ahead of print]
- Frese J, Morgenroth A, Mertens ME, Koch S, Rongen L, Vogg ATJ, Zlatopolskiy BD, Neumaier B, Gesche VN, Lammers T, Schmitz-Rode T, Mela P, Jockenhoevel S, Mottaghy FM, and Kiessling F. Nondestructive monitoring of tissue-engineered constructs. Biomed Tech. 2013 Sep 9. doi: 10.1515/bmt-2013-0029 [Epub ahead of print]
- Kiessling F. Science to practice: will contrast agents for molecular imaging of angiogenesis help overcome the limitations of functional vascular imaging? Radiology. 2013;268(2):309‑11.
- Fokong S, Fragoso A, Rix A, Curaj A, Wu Z, Lederle W, Iranzo O, Gätjens J, Kiessling F, and Palmowski M. Ultrasound Molecular Imaging of E-Selectin in Tumor Vessels Using Poly n-Butyl Cyanoacrylate Microbubbles Covalently Coupled to a Short Targeting Peptide. Invest Radiol. 2013;48(12):843‑50.
- Schulz V, Berker Y, Berneking A, Omidvari N, Kiessling F, Gola A, and Piemonte C. Sensitivity encoded silicon photomultiplier--a new sensor for high-resolution PET-MRI. Phys Med Biol. 2013;58(14):4733‑48.
- Simsekyilmaz S, Schreiber F, Weinandy S, Gremse F, Sönmez TT, and Liehn EA. A murine model of stent implantation in the carotid artery for the study of restenosis. J Vis Exp. 2013(75):e50233.
- Kiessling F. Science to Practice: exploring new indications for molecular US imaging. Radiology. 2013;267(3):661‑2.
- Siepmann M, Fokong S, Mienkina M, Lederle W, Kiessling F, Gätjens J, and Schmitz G. Phase shift variance imaging - a new technique for destructive microbubble imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2013;60(5):909‑23.
- Abou-Elkacem L, Arns S, Brix G, Gremse F, Zopf D, Kiessling F, and Lederle W. Regorafenib inhibits growth, angiogenesis, and metastasis in a highly aggressive, orthotopic colon cancer model. Mol Cancer Ther. 2013;12(7):1322‑31.
- Behrendt FF, Pietsch H, Jost G, Palmowski M, Günther RW, and Mahnken AH. Identification of the iodine concentration that yields the highest intravascular enhancement in MDCT angiography. AJR Am J Roentgenol. 2013;200(5):1151‑6.
- Rizzo LY, Theek B, Storm G, Kiessling F, and Lammers T. Recent progress in nanomedicine: therapeutic, diagnostic and theranostic applications. Curr Opin Biotechnol. 2013 Apr 9. doi: 10.1016/j.copbio.2013.02.020[Epub ahead of print]
- Lammers T. Smart drug delivery systems: back to the future vs. clinical reality. Int J Pharm. 2013;454(1):527‑9.
- Palmowski K, Winz O, Rix A, Bzyl J, Behrendt FF, Verburg FA, Mottaghy FM, and Palmowski M. Accuracy of a clinical PET/CT vs. a preclinical μPET system for monitoring treatment effects in tumour xenografts. Eur J Radiol. 2013;82(8):1318‑24.
- Ehling J, Bartneck M, Fech V, Butzbach B, Cesati R, Botnar R, Lammers T, and Tacke F. Elastin-based molecular MRI of liver fibrosis. Hepatology. 2013;58(4):1517‑8.
- Behrendt FF, Rebière M, Goedicke A, Pietsch H, Palmowski K, Kuhl CK, Mottaghy FM, and Verburg FA. Contrast medium injection protocol adjusted for body surface area in combined PET/CT. Eur Radiol. 2013;23(7):1970‑7.
- Ehling J, Lammers T, and Kiessling F. Non-invasive imaging for studying anti-angiogenic therapy effects.Thromb Haemost. 2013;109(3):375‑90.
- Akhtar S, Gremse F, Kiessling F, Weber C, and Schober A. CXCL12 promotes the stabilization of atherosclerotic lesions mediated by smooth muscle progenitor cells in Apoe-deficient mice. Arterioscler Thromb Vasc Biol. 2013;33(4):679‑86. Erratum in: Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):e125.
- Grouls C, Hatting M, Rix A, Pochon S, Lederle W, Tardy I, Kuhl CK, Trautwein C, Kiessling F, and Palmowski M. Liver dysplasia: US molecular imaging with targeted contrast agent enables early assessment. Radiology. 2013;267(2):487‑95.
- Depner S, Lederle W, Gutschalk C, Linde N, Zajonz A, and Mueller MM. Cell type specific interleukin-6 induced responses in tumor keratinocytes and stromal fibroblasts are essential for invasive growth. Int J Cancer. 2012 Nov 20. doi: 10.1002/ijc.27951 [Epub ahead of print]
- Talelli M, Oliveira S, Rijcken CJF, Pieters EHE, Etrych T, Ulbrich K, van Nostrum RCF, Storm G, Hennink WE, and Lammers T. Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy. Biomaterials. 2013;34(4):1255‑60.
- Kunjachan S, Gremse F, Theek B, Koczera P, Pola R, Pechar M, Etrych T, Ulbrich K, Storm G, Kiessling F, and Lammers T. Noninvasive optical imaging of nanomedicine biodistribution. ACS Nano. 2013;7(1):252‑62.
- Goedicke A, Berker Y, Verburg FA, Behrendt FF, Winz O, and Mottaghy FM. Study-parameter impact in quantitative 90-Yttrium PET imaging for radioembolization treatment monitoring and dosimetry. IEEE Trans Med Imaging. 2013;32(3):485‑92.
- Bzyl J, Palmowski M, Rix A, Arns S, Hyvelin J, Pochon S, Ehling J, Schrading S, Kiessling F, and Lederle W. The high angiogenic activity in very early breast cancer enables reliable imaging with VEGFR2-targeted microbubbles (BR55). Eur Radiol. 2013;23(2):468‑75.
- Keereman V, Mollet P, Berker Y, Schulz V, and Vandenberghe S. Challenges and current methods for attenuation correction in PET/MR. MAGMA. 2013;26(1):81‑98.
- Mühlenbruch G, Nikoubashman O, Steffen B, Dadak M, Palmowski M, and Wiesmann M. Endovascular broad-neck aneurysm creation in a porcine model using a vascular plug. Cardiovasc Intervent Radiol. 2013;36(1):239‑44.
- Goldschmidt B, Lerche CW, Solf T, Salomon A, Kiessling F, and Schulz V. Towards Software-Based Real-Time Singles and Coincidence Processing of Digital PET Detector Raw Data. IEEE Trans Nucl Sci. 2013;60(3):1550‑9.
- Mertens ME, Hermann A, Bühren A, Olde-Damink L, Möckel D, Gremse F, Ehling J, Kiessling F, and Lammers T. Iron Oxide-Labeled Collagen Scaffolds for Non-Invasive MR Imaging in Tissue Engineering. Adv Funct Mater. 2013. doi: 10.1002/adfm.201301275 [Epub ahead of print]
- Ruiz-Hernández E, Hess M, Melen G, Theek B, Talelli M, Shi Y, Ozbakir B, Teunissen E, Ramirez M, Moeckel D, Kiessling F, Storm G, Scheeren H, Hennink W, Szalay A, Stritzker J, and Lammers T. PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses. Polym Chem. 2013. doi: 10.1039/C3PY01097J [Epub ahead of print]
- Berker Y. Tie-breaking in round-robin soccer tournaments and its influence on the autonomy of relative rankings: UEFA vs. FIFA regulations. Eur Sport Manag Q. 2013;in press.
- Wehner J, Weissler B, Dueppenbecker P, Gebhardt P, Schug D, Ruetten W, Kiessling F, and Schulz V. PET/MRI insert using digital SiPMs: Investigation of MR-compatibility. Nucl Instrum Methods Phys Res Sect A. 2013. doi: 10.1016/j.nima.2013.08.077 [Epub ahead of print]
- Berker Y, Salomon A, Kiessling F, and Schulz V. Out-of-field activity in the estimation of mean lung attenuation coefficient in PET/MR. Nucl Instrum Methods Phys Res Sect A. 2013. doi: 10.1016/j.nima.2013.08.060 [Epub ahead of print]
- Kiessling F, and Lederle W. Personalizing Tumor Pathophysiology by Diagnosing Developmental Problems in Tumors with Imaging Techniques. In: Reichle A (Ed.). Evolution-adjusted Tumor Pathophysiology: The Novel Language of Tumor Biology. Dordrecht: Springer; 2013:323-341.
- Rizzo LY, Golombek S, Mertens M, Pan Y, Laaf D, Broda J, Moeckel D, Jayapaul J, Subr V, Hennink W, Storm G, Simon Z, Jahnen-Dechent W, Kiessling F, and Lammers T. In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay. J Mater Chem B. 2013;1:3918-25.
- Berker Y, Salomon A, Kiessling F, and Schulz V. Out-of-field accidentals in the estimation of mean lung attenuation coefficient in PET/MR [abstract]. J Nucl Med. 2013;54 Suppl 2:662.
- Richter B, Dirsch O, Gremse F, Zarafina S, Kiessling F, Settmacher U, and Dahmen U. Three-dimensional Reconstruction of the Architecture of the Biliary Tree During Cholestasis [abstract]. J Hepatol. 2013;58 Suppl 1:S282.
- Piemonte C, Gola A, Tarolli A, Fisher P, Ritzert M, Schulz V, and Solf T. Performance of FBK SiPMs coupled to PETA3 read-out ASIC for PET application. Nucl Instrum Methods Phys Res Sect A. 2013;718:345-6.
- Lerche CW, Mackewn J, Goldschmidt B, Salomon A, Gebbhardt P, Weissler B, Ayres R, Marsden P, and Schulz V. Calibration and stability of a SiPM-based simultaneous PET/MR insert. Nucl Instrum Methods Phys Res Sect A. 2013;702:50-3.
- Talelli M, Rijcken CJF, Hennink WE, and Lammers T. Polymeric micelles for cancer therapy: 3 C’s to enhance efficacy. Curr Opin Solid State Mater Sci. 2013;16(6):302-9.
- Fuge F, Weiler M, Gätjens J, Lammers T, and Kiessling F. Comparison and systematic optimization of synthetic protocols for DOTA–hydrazide generation. Tetrahedron Lett. 2013;54(8):918-20.
2012
- Baetke SC, Adriaens ME, Seigneuric R, Evelo CT, and Eijssen LMT. Molecular pathways involved in prostate carcinogenesis: insights from public microarray datasets. PLoS ONE. 2012;7(11):e49831.
- Bzyl J, Lederle W, Palmowski M, and Kiessling F. Molecular and functional ultrasound imaging of breast tumors. Eur J Radiol. 2012;81 Suppl 1:S11‑2.
- Tiebosch IACW, Crielaard BJ, Bouts MJRJ, Zwartbol R, Salas-Perdomo A, Lammers T, Planas AM, Storm G, and Dijkhuizen RM. Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic stroke in rats. J Neurochem. 2012;123 Suppl 2:65‑74.
- Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, Heyll K, Gremse F, Kiessling F, Grommes J, Weber C, and Schober A. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest. 2012;122(11):4190‑202.
- Bartneck M, Ritz T, Keul HA, Wambach M, Bornemann J, Gbureck U, Ehling J, Lammers T, Heymann F, Gassler N, Lüdde T, Trautwein C, Groll J, and Tacke F. Peptide-functionalized gold nanorods increase liver injury in hepatitis. ACS Nano. 2012;6(10):8767‑77.
- Kiessling F. Science to practice: genetic engineering meets cell tracking--a promising approach for cell-based therapies? Radiology. 2012;265(1):1‑3.
- Jayapaul J, Arns S, Lederle W, Lammers T, Comba P, Gätjens J, and Kiessling F. Riboflavin carrier protein-targeted fluorescent USPIO for the assessment of vascular metabolism in tumors. Biomaterials. 2012;33(34):8822‑9.
- Salomon A, Goldschmidt B, Botnar R, Kiessling F, and Schulz V. A self-normalization reconstruction technique for PET scans using the positron emission data. IEEE Trans Med Imaging. 2012;31(12):2234‑40.
- Leonard F, Ali H, Collnot E, Crielaard BJ, Lammers T, Storm G, and Lehr C. Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model. ALTEX. 2012;29(3):275‑85.
- Lammers T, Rizzo LY, Storm G, and Kiessling F. Personalized nanomedicine. Clin Cancer Res. 2012;18(18):4889‑94.
- Prechtel HWE, Verburg FA, Palmowski M, Krohn T, Pietsch H, Kuhl CK, Mottaghy FM, and Behrendt FF. Different intravenous contrast media concentrations do not affect clinical assessment of 18F-fluorodeoxyglucose positron emission tomography/computed tomography scans in an intraindividual comparison. Invest Radiol. 2012;47(9):497‑502.
- Braun K, Beining M, Wiessler M, Lammers T, Pipkorn R, Hennrich U, Nokihara K, Semmler W, Debus J, and Waldeck W. BioShuttle mobility in living cells studied with high-resolution FCS & CLSM methodologies. Int J Med Sci. 2012;9(5):339‑52.
- Crielaard BJ, Rijcken CJF, Quan L, van der Wal S, Altintas I, van der Pot M, Kruijtzer JAW, Liskamp RMJ, Schiffelers RM, van Nostrum CF, Hennink WE, Wang D, Lammers T, and Storm G. Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis.Angew Chem Int Ed Engl. 2012;51(29):7254‑8.
- Lammers T. Drug delivery research in Europe. J Control Release. 2012;161(2):151.
- Rebière M, Verburg FA, Palmowski M, Krohn T, Pietsch H, Kuhl CK, Mottaghy FM, and Behrendt FF. Multiphase CT scanning and different intravenous contrast media concentrations in combined F-18-FDG PET/CT: Effect on quantitative and clinical assessment. Eur J Radiol. 2012;81(8):e862‑9.
- Fokong S, Theek B, Wu Z, Koczera P, Appold L, Jorge S, Resch-Genger U, van Zandvoort M, Storm G, Kiessling F, and Lammers T. Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles. J Control Release. 2012;163(1):75‑81.
- te Boekhorst BCM, Jensen LB, Colombo S, Varkouhi AK, Schiffelers RM, Lammers T, Storm G, Nielsen HM, Strijkers GJ, Foged C, and Nicolay K. MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model. J Control Release. 2012;161(3):772‑80.
- Abou-Elkacem L, Björn S, Doleschel D, Ntziachristos V, Schulz R, Hoffman RM, Kiessling F, and Lederle W. High accuracy of mesoscopic epi-fluorescence tomography for non-invasive quantitative volume determination of fluorescent protein-expressing tumours in mice. Eur Radiol. 2012;22(9):1955‑62.
- Wu Z, Chen K, Yildiz I, Dirksen A, Fischer R, Dawson PE, and Steinmetz NF. Development of viral nanoparticles for efficient intracellular delivery. Nanoscale. 2012;4(11):3567‑76.
- Berker Y, Franke J, Salomon A, Palmowski M, Donker HCW, Temur Y, Mottaghy FM, Kuhl C, Izquierdo-Garcia D, Fayad ZA, Kiessling F, and Schulz V. MRI-based attenuation correction for hybrid PET/MRI systems: a 4-class tissue segmentation technique using a combined ultrashort-echo-time/Dixon MRI sequence. J Nucl Med. 2012;53(5):796‑804. Erratum in: J Nucl Med. 2012 Sep;53(9):1496.
- Grouls C, Hatting M, Tardy I, Bzyl J, Mühlenbruch G, Behrendt FF, Penzkofer T, Trautwein C, Kuhl C, Kiessling F, and Palmowski M. Development and validation of an intrinsic landmark-based gating protocol applicable for functional and molecular ultrasound imaging. Eur Radiol. 2012;22(8):1789‑96.
- Kiessling F, Fokong S, Koczera P, Lederle W, and Lammers T. Ultrasound microbubbles for molecular diagnosis, therapy, and theranostics. J Nucl Med. 2012;53(3):345‑8.
- Lammers T. Nanomedicine on the move: from monotherapeutic regimens to combination therapies. Expert Rev Clin Pharmacol. 2012;5(2):105‑8.
- Kiessling F, Bzyl J, Fokong S, Siepmann M, Schmitz G, and Palmowski M. Targeted ultrasound imaging of cancer: an emerging technology on its way to clinics. Curr Pharm Des. 2012;18(15):2184‑99.
- Hodenius M, Würth C, Jayapaul J, Wong JE, Lammers T, Gätjens J, Arns S, Mertens N, Slabu I, Ivanova G, Bornemann J, Cuyper MD, Resch-Genger U, and Kiessling F. Fluorescent magnetoliposomes as a platform technology for functional and molecular MR and optical imaging. Contrast Media Mol Imaging. 2012;7(1):59‑67.
- Linde N, Lederle W, Depner S, van Rooijen N, Gutschalk CM, and Mueller MM. Vascular endothelial growth factor-induced skin carcinogenesis depends on recruitment and alternative activation of macrophages. J Pathol. 2012;227(1):17‑28.
- Sahin H, Borkham-Kamphorst E, Kuppe C, Zaldivar MM, Grouls C, Al-samman M, Nellen A, Schmitz P, Heinrichs D, Berres M, Doleschel D, Scholten D, Weiskirchen R, Moeller MJ, Kiessling F, Trautwein C, and Wasmuth HE. Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice. Hepatology. 2012;55(5):1610‑9.
- Doleschel D, Mundigl O, Wessner A, Gremse F, Bachmann J, Rodriguez A, Klingmüller U, Jarsch M, Kiessling F, and Lederle W. Targeted near-infrared imaging of the erythropoietin receptor in human lung cancer xenografts. J Nucl Med. 2012;53(2):304‑11.
- Crielaard BJ, Lammers T, Schiffelers RM, and Storm G. Drug targeting systems for inflammatory disease: one for all, all for one. J Control Release. 2012;161(2):225‑34.
- Lederle W, Palmowski M, and Kiessling F. Imaging in the age of molecular medicine: monitoring of anti-angiogenic treatments. Curr Pharm Biotechnol. 2012;13(4):595‑608.
- Kunjachan S, Jayapaul J, Mertens ME, Storm G, Kiessling F, and Lammers T. Theranostic systems and strategies for monitoring nanomedicine-mediated drug targeting. Curr Pharm Biotechnol. 2012;13(4):609‑22.
- Kiessling F. Imaging in the age of molecular medicine. Curr Pharm Biotechnol. 2012;13(4):497.
- Rix A, Lederle W, Siepmann M, Fokong S, Behrendt FF, Bzyl J, Grouls C, Kiessling F, and Palmowski M. Evaluation of high frequency ultrasound methods and contrast agents for characterising tumor response to anti-angiogenic treatment. Eur J Radiol. 2012;81(10):2710‑6.
- Jensen LB, Griger J, Naeye B, Varkouhi AK, Raemdonck K, Schiffelers R, Lammers T, Storm G, de Smedt SC, Sproat BS, Nielsen HM, and Foged C. Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression. Pharm Res. 2012;29(3):669‑82.
- Lammers T, Kiessling F, Hennink WE, and Storm G. Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress. J Control Release. 2012;161(2):175‑87.
- Varkouhi AK, Mountrichas G, Schiffelers RM, Lammers T, Storm G, Pispas S, and Hennink WE. Polyplexes based on cationic polymers with strong nucleic acid binding properties. Eur J Pharm Sci. 2012;45(4):459‑66.
- Crielaard BJ, van der Wal S, Le HT, Bode ATL, Lammers T, Hennink WE, Schiffelers RM, Fens MHAM, and Storm G. Liposomes as carriers for colchicine-derived prodrugs: vascular disrupting nanomedicines with tailorable drug release kinetics. Eur J Pharm Sci. 2012;45(4):429‑35.
- Kunjachan S, Błauż A, Möckel D, Theek B, Kiessling F, Etrych T, Ulbrich K, van Bloois L, Storm G, Bartosz G, Rychlik B, and Lammers T. Overcoming cellular multidrug resistance using classical nanomedicine formulations. Eur J Pharm Sci. 2012;45(4):421‑8.
- Cittadino E, Ferraretto M, Torres E, Maiocchi A, Crielaard BJ, Lammers T, Storm G, Aime S, and Terreno E. MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate. Eur J Pharm Sci. 2012;45(4):436‑41.
- Kunjachan S, Jose S, Thomas CA, Joseph E, Kiessling F, and Lammers T. Physicochemical and biological aspects of macrophage-mediated drug targeting in anti-microbial therapy. Fundam Clin Pharmacol. 2012;26(1):63‑71.
- Buerger C, Tsoumpas C, Aitken A, King AP, Schleyer P, Schulz V, Marsden PK, and Schaeffter T. Investigation of MR-Based Attenuation Correction and Motion Compensation for Hybrid PET/MR. IEEE Trans Nucl Sci. 2012;59(5):1967‑76.
- Schulz V, Berker Y, Berneking A, Omidvari N, Kiessling F, Gola A, and Piemonte C. A 2D Sensitivity Encoded Silicon Photomultiplier (SeSP) for simultaneous high resolution PET/MR scanners. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:3743‑5.
- Duppenbecker PM, Weissler B, Gebhardt P, Schug D, Wehner J, Marsden PK, and Schulz V. Development of an MRI compatible digital SiPM based PET detector stack for simultaneous preclinical PET/MRI. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:3481‑3.
- Duppenbecker PM, Wehner J, Renz W, Lodomez S, Truhn D, Marsden PK, and Schulz V. Gradient transparent RF housing for simultaneous PET/MRI using carbon fiber composites. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:3478‑80.
- Schug D, Duppenbecker PM, Gebhardt P, Weissler B, Zwaans B, Kiessling F, and Schulz V. First evaluations of the neighbor logic of the digital SiPM tile. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2817‑9.
- Lerche CW, Mackewn JE, Ayres R, Weissler B, Gebhardt P, Solf T, Goldschmidt B, Salomon A, Sunassee K, Marsden PK, and Schulz V. MR image quality and timing resolution of an analog SiPM based pre-clinical PET/MR insert. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2802‑6.
- Mackewn JE, Lerche CW, Sunassee K, de Rosales RTM, Phinikaridou A, Salomon A, Ayres R, Tsoumpas C, Soultanidis GM, Schaeffter T, Marsden PK, and Schulz V. PET performance evaluation of a pre-clinical SiPM based MR-compatible PET scanner. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2776‑9.
- Weissler B, Gebhardt P, Zinke M, Kiessling F, and Schulz V. An MR-compatible singles detection and processing unit for simultaneous preclinical PET/MR. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2759‑61.
- Gebhardt P, Weissler B, Zinke M, Kiessling F, Marsden PK, and Schulz V. FPGA-based singles and coincidences processing pipeline for integrated digital PET/MR detectors. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2479‑82.
- Berker Y, Kiessling F, and Schulz V. Use of scattered coincidences for emission-based estimation of attenuation map in PET. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2285‑7.
- Berker Y, Salomon A, Kiessling F, and Schulz V. Lung attenuation coefficient estimation using Maximum Likelihood reconstruction of attenuation and activity for PET/MR attenuation correction. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2282‑4.
- Weissler B, Gebhardt P, Duppenbecker P, Goldschmidt B, Salomon A, Schug D, Wehner J, Lerche C, Wirtz D, Renz W, Schumacher K, Zwaans B, Marsden P, Kiessling F, and Schulz V. Design concept of world's first preclinical PET/MR insert with fully digital silicon photomultiplier technology. 2012 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2012:2113‑6.
- Al Rawashdeh W, Kray S, Pich A, Pargen S, Balaceanu A, Lenz M, Spöler F, Kiessling F, and Lederle W. Polymeric nanoparticles as OCT contrast agents. J Nanopart Res. 2012;14(12):1255.
- Frese J, Schuster P, Mertens ME, Vogg A, Dahlems U, Rongen L, Koch S, Mela P, Melmer G, Barth S, Mottaghy FM, Schmitz-Rode T, Lammers T, Jockenhoevel S, and Kiessling F. Generation and imaging of patient customized implants. Biomed Tech. 2012;57 Suppl 1.
- Frese J, Hrdlicka L, Mertens ME, Rongen L, Koch S, Schuster P, Gesché VN, Lammers T, Mela P, Kiessling F, and Jockenhoevel S. Non-invasive Imaging of Tissue-Engineered Vascular Endothelium with Iron Oxide Nanoparticles. Biomed Tech. 2012;57 Suppl 1;1065-7.
- Siepmann M, Bzyl J, Fokong S, Kiessling F, and Schmitz G. Quantitative Phase Shift Variance Imaging. Biomed Tech. 2012;57 Suppl 1;184-7.
- Koczera P, Wu Z, Fokong S, Theek B, Appold L, Jorge S, Möckel D, Liu Z, Curaj A, Storm G, van Zandvoort M, Kiessling F, and Lammers T. Fluorescently labeled microbubbles for facilitating translational molecular ultrasound studies. Drug Deliv Transl Res. 2012;2(1):56-64.
- Jayapaul J, Truhn D, Lüdtke-Buzug K, Buzug TM, and Kiessling F. Initial MPS Response of Adsorptively-Coated Fluorescent Iron Oxide Nanoparticles. Springer Proc Phys. 2012;140(2):47-52.
2011
- Lederle W, Arns S, Rix A, Gremse F, Doleschel D, Schmaljohann J, Mottaghy FM, Kiessling F, and Palmowski M. Failure of annexin-based apoptosis imaging in the assessment of antiangiogenic therapy effects. EJNMMI Res. 2011;1(1):26.
- Wiessler M, Hennrich U, Pipkorn R, Waldeck W, Cao L, Peter J, Ehemann V, Semmler W, Lammers T, and Braun K. Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy. Theranostics. 2011;1:381‑94.
- Liehn EA, Tuchscheerer N, Kanzler I, Drechsler M, Fraemohs L, Schuh A, Koenen RR, Zander S, Soehnlein O, Hristov M, Grigorescu G, Urs AO, Leabu M, Bucur I, Merx MW, Zernecke A, Ehling J, Gremse F, Lammers T, Kiessling F, Bernhagen J, Schober A, and Weber C. Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J Am Coll Cardiol. 2011;58(23):2415‑23.
- Crielaard BJ, van der Wal S, Lammers T, Le HT, Hennink WE, Schiffelers RM, Storm G, and Fens MH. A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy. Int J Nanomedicine. 2011;6:2697‑703.
- Talelli M, Morita K, Rijcken CJF, Aben RWM, Lammers T, Scheeren HW, van Nostrum CF, Storm G, and Hennink WE. Synthesis and characterization of biodegradable and thermosensitive polymeric micelles with covalently bound doxorubicin-glucuronide prodrug via click chemistry. Bioconjug Chem. 2011;22(12):2519‑30.
- Fokong S, Siepmann M, Liu Z, Schmitz G, Kiessling F, and Gätjens J. Advanced characterization and refinement of poly N-butyl cyanoacrylate microbubbles for ultrasound imaging. Ultrasound Med Biol. 2011;37(10):1622‑34.
- Berker Y, Goedicke A, Kemerink GJ, Aach T, and Schweizer B. Activity quantification combining conjugate-view planar scintigraphies and SPECT/CT data for patient-specific 3-D dosimetry in radionuclide therapy. Eur J Nucl Med Mol Imaging. 2011;38(12):2173‑85.
- Huis In 't Veld R, Storm G, Hennink WE, Kiessling F, and Lammers T. Macromolecular nanotheranostics for multimodal anticancer therapy. Nanoscale. 2011;3(10):4022‑34.
- Abou-Elkacem L, Gremse F, Barth S, Hoffman RM, Kiessling F, and Lederle W. Comparison of μCT, MRI and optical reflectance imaging for assessing the growth of GFP/RFP-expressing tumors. Anticancer Res. 2011;31(9):2907‑13.
- Truhn D, Kiessling F, and Schulz V. Optimized RF shielding techniques for simultaneous PET/MR. Med Phys. 2011;38(7):3995‑4000.
- Kiessling FM. Science to practice: are theranostic agents with encapsulated cells the key for diabetes therapy? Radiology. 2011;260(3):613‑5.
- Crielaard BJ, Yousefi A, Schillemans JP, Vermehren C, Buyens K, Braeckmans K, Lammers T, and Storm G. An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes. J Control Release. 2011;156(3):307‑14.
- Xiao L, Li J, Brougham DF, Fox EK, Feliu N, Bushmelev A, Schmidt A, Mertens N, Kiessling F, Valldor M, Fadeel B, and Mathur S. Water-soluble superparamagnetic magnetite nanoparticles with biocompatible coating for enhanced magnetic resonance imaging. ACS Nano. 2011;5(8):6315‑24.
- Gremse F, Grouls C, Palmowski M, Lammers T, de Vries A, Grüll H, Das M, Mühlenbruch G, Akhtar S, Schober A, and Kiessling F. Virtual elastic sphere processing enables reproducible quantification of vessel stenosis at CT and MR angiography. Radiology. 2011;260(3):709‑17.
- Liu Z, Lammers T, Ehling J, Fokong S, Bornemann J, Kiessling F, and Gätjens J. Iron oxide nanoparticle-containing microbubble composites as contrast agents for MR and ultrasound dual-modality imaging. Biomaterials. 2011;32(26):6155‑63.
- Jayapaul J, Hodenius M, Arns S, Lederle W, Lammers T, Comba P, Kiessling F, and Gaetjens J. FMN-coated fluorescent iron oxide nanoparticles for RCP-mediated targeting and labeling of metabolically active cancer and endothelial cells. Biomaterials. 2011;32(25):5863‑71.
- Bzyl J, Lederle W, Rix A, Grouls C, Tardy I, Pochon S, Siepmann M, Penzkofer T, Schneider M, Kiessling F, and Palmowski M. Molecular and functional ultrasound imaging in differently aggressive breast cancer xenografts using two novel ultrasound contrast agents (BR55 and BR38). Eur Radiol. 2011;21(9):1988‑95.
- Kiessling F, Gaetjens J, and Palmowski M. Application of molecular ultrasound for imaging integrin expression. Theranostics. 2011;1:127‑34.
- Lammers T, Aime S, Hennink WE, Storm G, and Kiessling F. Theranostic nanomedicine. Acc Chem Res. 2011;44(10):1029‑38.
- Varkouhi AK, Foillard S, Lammers T, Schiffelers RM, Doris E, Hennink WE, and Storm G. SiRNA delivery with functionalized carbon nanotubes. Int J Pharm. 2011;416(2):419‑25.
- Talelli M, Rijcken CJF, Oliveira S, van der Meel R, van Bergen En Henegouwen PMP, Lammers T, van Nostrum CF, Storm G, and Hennink WE. Nanobody-shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting. J Control Release. 2011;151(2):183‑92.
- Crielaard BJ, Lammers T, Morgan ME, Chaabane L, Carboni S, Greco B, Zaratin P, Kraneveld AD, and Storm G. Macrophages and liposomes in inflammatory disease: friends or foes? Int J Pharm. 2011;416(2):499‑506.
- Kostka L, Konák C, Subr V, Spírková M, Addadi Y, Neeman M, Lammers T, and Ulbrich K. Removable nanocoatings for siRNA polyplexes. Bioconjug Chem. 2011;22(2):169‑79.
- Salomon A, Goedicke A, Schweizer B, Aach T, and Schulz V. Simultaneous reconstruction of activity and attenuation for PET/MR. IEEE Trans Med Imaging. 2011;30(3):804‑13.
- Varkouhi AK, Lammers T, Schiffelers RM, van Steenbergen MJ, Hennink WE, and Storm G. Gene silencing activity of siRNA polyplexes based on biodegradable polymers. Eur J Pharm Biopharm. 2011;77(3):450‑7.
- Schulz V, Torres-Espallardo I, Renisch S, Hu Z, Ojha N, Börnert P, Perkuhn M, Niendorf T, Schäfer WM, Brockmann H, Krohn T, Buhl A, Günther RW, Mottaghy FM, and Krombach GA. Automatic, three-segment, MR-based attenuation correction for whole-body PET/MR data. Eur J Nucl Med Mol Imaging. 2011;38(1):138‑52.
- Lederle W, Depner S, Schnur S, Obermueller E, Catone N, Just A, Fusenig NE, and Mueller MM. IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines. Int J Cancer. 2011;128(12):2803‑14.
- Kiessling I, Bzyl J, and Kiessling F. Molecular ultrasound imaging and its potential for paediatric radiology. Pediatr Radiol. 2011;41(2):176‑84.
- Mlotok V, Ritzert M, Fischer P, Peric I, Solf T, and Schulz V. Floodmap measurement of a pixellated gamma scintillation detector module using fully integrated readout. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:1980‑1.
- Duppenbecker PM, Haagen R, Lodomez S, Marsden PK, and Schulz V. A method for measuring the sub-pixel light distribution of scintillation detectors with digital SiPMs. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:2301‑2.
- Goldschmidt B, Lerche CW, Solf T, Salomon A, Kiessling F, and Schulz V. Singles and coincidence processing for a digital PET/MR system using SiPM detectors. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:3922‑4.
- Lerche CW, Solf T, Dueppenbecker P, Goldschmidt B, Marsden PK, and Schulz V. Maximum likelihood based positioning and energy correction for pixelated solid state PET detectors. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:3610‑3.
- King AP, Tsoumpas C, Buerger C, Schulz V, Marsden P, and Schaeffter T. Real-time respiratory motion correction for simultaneous PET-MR using an MR-derived motion model. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:3589‑94.
- Soultanidis GM, Mackewn JE, Lerche CW, Tsoumpas C, Buerger C, Szanda I, Halsted P, Schaeffter T, Schulz V, and Marsden PK. Design and development of phantoms capable of continuous motion during simultaneous PET-MR acquisitions. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:3567‑71.
- Buerger C, Aitken A, Tsoumpas C, King AP, Schulz V, Marsden P, and Schaeffter T. Investigation of 4D PET attenuation correction using Ultra-short Echo Time MR. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:3558‑61.
- Salomon A, Truhn D, Botnar R, Kiessling F, and Schulz V. Sparse crystal setting and large axial FOV for integrated whole-body PET/MR. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:2521‑3.
- Schulz V, Dueppenbecker P, Lerche CW, Gola A, Ferri A, Tarolli A, and Piemonte C. Sensitivity Encoded Silicon Photomultipliers (SeSPs): A novel detector design for uniform crystal identification. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:3027‑9.
- Schulz V, Weissler B, Gebhardt P, Solf T, Lerche CW, Fischer P, Ritzert M, Mlotok V, Piemonte C, Goldschmidt B, Vandenberghe S, Salomon A, Schaeffter T, and Marsden PK. SiPM based preclinical PET/MR insert for a human 3T MR: first imaging experiments. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:4467‑9.
- Duppenbecker PM, Lodomez S, Haagen R, Marsden PK, and Schulz V. Investigation of a sub-millimeter resolution PET detector with depth of interaction encoding using digital SiPM single sided readout. 2011 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2011:2252‑3.
- Kiessling F, Schmitz G, and Gätjens J. Design and use of contrast agents for ultrasound imaging. In: Braddock M (Ed.). Biomedical Imaging: The Chemistry of Labels, Probes and Contrast Agents. Cambridge: Royal Society of Chemistry; 2012:391-410.
2010
- Lammers T, Storm G, and Kiessling F. Nanomedicine formulations for combination therapies. Nano Rev. 2010;1.
- Schoth F, Persigehl T, and Palmowski M. Current role and future perspective of MRI for diagnosis and characterization of renal cell carcinoma. Panminerva Med. 2010;52(4):307‑18.
- Lammers T, Subr V, Ulbrich K, Peschke P, Huber PE, Hennink WE, Storm G, and Kiessling F. HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations. Nanomedicine. 2010;5(10):1501‑23.
- Varkouhi AK, Verheul RJ, Schiffelers RM, Lammers T, Storm G, and Hennink WE. Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan. Bioconjug Chem. 2010;21(12):2339‑46.
- Lammers T, Kiessling F, Hennink WE, and Storm G. Nanotheranostics and image-guided drug delivery: current concepts and future directions. Mol Pharm. 2010;7(6):1899‑912.
- Talelli M, Iman M, Varkouhi AK, Rijcken CJF, Schiffelers RM, Etrych T, Ulbrich K, van Nostrum CF, Lammers T, Storm G, and Hennink WE. Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin. Biomaterials. 2010;31(30):7797‑804.
- Kiessling F. Science to practice: the dawn of molecular US imaging for clinical cancer imaging. Radiology. 2010;256(2):331‑3.
- Brix G, Griebel J, Kiessling F, and Wenz F. Tracer kinetic modelling of tumour angiogenesis based on dynamic contrast-enhanced CT and MRI measurements. Eur J Nucl Med Mol Imaging. 2010;37 Suppl 1:S30‑51.
- Kiessling F, Razansky D, and Alves F. Anatomical and microstructural imaging of angiogenesis. Eur J Nucl Med Mol Imaging. 2010;37 Suppl 1:S4‑19.
- Kampmeier F, Niesen J, Koers A, Ribbert M, Brecht A, Fischer R, Kiessling F, Barth S, and Thepen T. Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein. Eur J Nucl Med Mol Imaging. 2010;37(10):1926‑34.
- Brix G, Zwick S, Griebel J, Fink C, and Kiessling F. Estimation of tissue perfusion by dynamic contrast-enhanced imaging: simulation-based evaluation of the steepest slope method. Eur Radiol. 2010;20(9):2166‑75.
- Woenne EC, Lederle W, Zwick S, Palmowski M, Krell H, Semmler W, Mueller MM, and Kiessling F. MMP inhibition blocks fibroblast-dependent skin cancer invasion, reduces vascularization and alters VEGF-A and PDGF-BB expression. Anticancer Res. 2010;30(3):703‑11.
- Kuntz J, Dinkel J, Zwick S, Bäuerle T, Grasruck M, Kiessling F, Gupta R, Semmler W, and Bartling SH. Fully automated intrinsic respiratory and cardiac gating for small animal CT. Phys Med Biol. 2010;55(7):2069‑85.
- Lederle W, Linde N, Heusel J, Bzyl J, Woenne EC, Zwick S, Skobe M, Kiessling F, Fusenig NE, and Mueller MM. Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas. Am J Pathol. 2010;176(2):981‑94.
- Lammers T, and Ulbrich K. HPMA copolymers: 30 years of advances. Adv Drug Deliv Rev. 2010;62(2):119‑21.
- Lammers T. Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations. Adv Drug Deliv Rev. 2010;62(2):203‑30.
- Palmowski M, Lederle W, Gaetjens J, Socher M, Hauff P, Bzyl J, Semmler W, Günther RW, and Kiessling F. Comparison of conventional time-intensity curves vs. maximum intensity over time for post-processing of dynamic contrast-enhanced ultrasound. Eur J Radiol. 2010;75(1):e149‑53.
- Lederle W, Hartenstein B, Meides A, Kunzelmann H, Werb Z, Angel P, and Mueller MM. MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma. Carcinogenesis. 2010;31(7):1175‑84.
- Tabares LC, Gätjens J, and Un S. Understanding the influence of the protein environment on the Mn(II) centers in Superoxide Dismutases using High-Field Electron Paramagnetic Resonance. Biochim Biophys Acta. 2010;1804(2):308‑17.
- Zwick S, Brix G, Tofts PS, Strecker R, Kopp-Schneider A, Laue H, Semmler W, and Kiessling F. Simulation-based comparison of two approaches frequently used for dynamic contrast-enhanced MRI. Eur Radiol. 2010;20(2):432‑42.
- Palmowski M, Schifferdecker I, Zwick S, Macher-Goeppinger S, Laue H, Haferkamp A, Kauczor H, Kiessling F, and Hallscheidt P. Tumor perfusion assessed by dynamic contrast-enhanced MRI correlates to the grading of renal cell carcinoma: initial results. Eur J Radiol. 2010;74(3):e176‑80.
- Bäuerle T, Bartling S, Berger M, Schmitt-Gräff A, Hilbig H, Kauczor H, Delorme S, and Kiessling F. Imaging anti-angiogenic treatment response with DCE-VCT, DCE-MRI and DWI in an animal model of breast cancer bone metastasis. Eur J Radiol. 2010;73(2):280‑7.
- Hu Z, Renisch S, Schweizer B, Blaffert T, Ojha N, Guo T, Tang J, Tung C, Kaste J, Schulz V, Torres I, and Shao L. MR-based attenuation correction for whole-body PET/MR system. IEEE Nucl Sci Symp Med Imaging Conf. 2010:2119‑22.
- Piemonte C, Gola A, Mazzuca E, Piazza A, Tarolli A, Zorzi N, Schulz V, and Solf T. Timing performance of 4×4mm2 SiPMs with different cell layout coupled to LYSO scintillator. IEEE Nucl Sci Symp Med Imaging Conf. 2010:1804‑8.
- Kiessling F, and Pichler B. Small Animal Imaging – Basics and Practical Guide. Berlin: Springer; 2010.
- Kiessling F, Pichler B, and Hauff P. How to choose the right imaging modality? In: Kiessling F, Pichler B (Eds.). Small Animal Imaging – Basics and Practical Guide. Berlin: Springer; 2010:119-25Weber WA, and Kiessling F. Imaging in Oncology Research. In: Kiessling F, Pichler B (Eds.). Small Animal Imaging – Basics and Practical Guide. Berlin: Springer; 2010:543-65.
- Kiessling F, and Lederle W. Early Detection of Systems Response: Molecular and Functional Imaging of Angiogenesis. In: Reichle A (Ed.). From Molecular to Modular Tumor Therapy: Tumors are Reconstructible Communicatively Evolving Systems. Berlin: Springer; 2010:385-405. (The Tumor Microenvironment; vol. 3).
- Lammers T, Subr V, Ulbrich K, Hennink WE, Storm G, and Kiessling F. Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy. Nano Today. 2010;5(3):197-212.
- Lammers T, Subr V, Ulbrich K, Peschke P, Huber PE, Hennink WE, Storm G, and Kiessling F. Long‐Circulating and Passively Tumor‐Targeted Polymer‐Drug Conjugates Improve the Efficacy and Reduce the Toxicity of Radiochemotherapy. Adv Eng Mater. 2010;12(9):B413–21.
- Liu Z, Kiessling F, and Gätjens J. Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications. J Nanomater. 2010:894303.
2009
- Neukamm M, Palmowski M, Bartling S, Schawo S, Rietdorf U, Meinzer H, Hohenfellner M, Kauczor H, and Hallscheidt P. Intrarenal artery delineation with ultra high resolution, flat panel based, volume computerized tomography: outer limits of spatial resolution. J Urol. 2009;182(6):2915‑9.
- Kiessling F, Huppert J, Zhang C, Jayapaul J, Zwick S, Woenne EC, Mueller MM, Zentgraf H, Eisenhut M, Addadi Y, Neeman M, and Semmler W. RGD-labeled USPIO inhibits adhesion and endocytotic activity of alpha v beta3-integrin-expressing glioma cells and only accumulates in the vascular tumor compartment. Radiology. 2009;253(2):462‑9.
- Palmowski M, Peschke P, Huppert J, Hauff P, Reinhardt M, Maurer M, Karger CP, Scholz M, Semmler W, Huber PE, and Kiessling FM. Molecular ultrasound imaging of early vascular response in prostate tumors irradiated with carbon ions. Neoplasia. 2009;11(9):856‑63.
- Brix G, Zwick S, Kiessling F, and Griebel J. Pharmacokinetic analysis of tissue microcirculation using nested models: multimodel inference and parameter identifiability. Med Phys. 2009;36(7):2923‑33.
- Vosseler S, Lederle W, Airola K, Obermueller E, Fusenig NE, and Mueller MM. Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion. Int J Cancer. 2009;125(10):2296‑306.
- Aviv H, Bartling S, Kieslling F, and Margel S. Radiopaque iodinated copolymeric nanoparticles for X-ray imaging applications. Biomaterials. 2009;30(29):5610‑6.
- Palmowski M, Palmowski M, Hauff P, and Kiessling F. [Molecular imaging in oncology using targeted ultrasound contrast agents]. Praxis. 2009;98(11):597‑602.
- Kramer S, Palmowski M, Macher-Göppinger S, Müller M, Volke F, Düx M, Kauczor H, and Grenacher L. [High-resolution imaging of the layers of the gastrointestinal wall of pig and human specimens using an endoluminal MR receiver coil: correlation to histology]. Rofo. 2009;181(11):1073‑80.
- Zwick S, Strecker R, Kiselev V, Gall P, Huppert J, Palmowski M, Lederle W, Woenne EC, Hengerer A, Taupitz M, Semmler W, and Kiessling F. Assessment of vascular remodeling under antiangiogenic therapy using DCE-MRI and vessel size imaging. J Magn Reson Imaging. 2009;29(5):1125‑33.
- Sauerbier S, Palmowski M, Vogeler M, Nagursky H, Al-Ahmad A, Fisch D, Hennig J, Schmelzeisen R, Gutwald R, and Fasol U. Onset and maintenance of angiogenesis in biomaterials: in vivo assessment by dynamic contrast-enhanced MRI. Tissue Eng Part C Methods. 2009;15(3):455‑62.
- Kiessling F, Huppert J, and Palmowski M. Functional and molecular ultrasound imaging: concepts and contrast agents. Curr Med Chem. 2009;16(5):627‑42.
- Reiss Y, Knedla A, Tal AO, Schmidt MHH, Jugold M, Kiessling F, Burger AM, Wolburg H, Deutsch U, and Plate KH. Switching of vascular phenotypes within a murine breast cancer model induced by angiopoietin-2. J Pathol. 2009;217(4):571‑80.
- Carmona G, Göttig S, Orlandi A, Scheele J, Bäuerle T, Jugold M, Kiessling F, Henschler R, Zeiher AM, Dimmeler S, and Chavakis E. Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. Blood. 2009;113(2):488‑97.
- Heye T, Kuntz C, Düx M, Encke J, Palmowski M, Autschbach F, Volke F, Kauffmann GW, and Grenacher L. CT and endoscopic ultrasound in comparison to endoluminal MRI: preliminary results in staging gastric carcinoma. Eur J Radiol. 2009;70(2):336‑41.
- Ritzert M, Fischer P, Mlotok V, Peri I, Piemonte C, Zorzi N, Schulz V, Solf T, and Thon A. Compact SiPM based detector module for time-of-flight PET/MR. IEEE Real Time Conf. 2009:163‑6.
- Schulz V, Solf T, Weissler B, Gebhardt P, Fischer P, Ritzert M, Mlotok V, Piemonte C, Zorzi N, Melchiorri M, Vandenberghe S, Keereman V, Schaeffter T, and Marsden P. A preclinical PET/MR insert for a human 3T MR scanner. 2009 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2009:2577‑9.
- Vandenberghe S, Keereman V, Staelens S, Schulz V, and Marsden P. Effect of geometrical constraints on PET performance in whole body simultaneous PET-MR. 2009 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2009:3808‑11.
- Keereman V, Vandenberghe S, De Beenhouwer J, Van Holen R, Staelens S, Schulz V, and Solf T. Scatter effects of MR components in PET-MR inserts. 2009 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2009:3804‑7.
- Hu Z, Ojha N, Renisch S, Schulz V, Torres I, Buhl A, Pal D, Muswick G, Penatzer J, Guo T, Bonert P, Tung C, Kaste J, Morich M, Havens T, Maniawski P, Schafer W, Gunther R, Krombach G, and Shao L. MR-based attenuation correction for a whole-body sequential PET/MR system. 2009 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2009:3508‑12.
- Tsoumpas C, Buerger C, King A, Keereman V, Vandenberghe S, Schulz V, Schaeffter T, and Marsden P. Simulation of dynamic PET data from real MR acquisitions. 2009 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2009:3065‑8.
- Solf T, Schulz V, Weissler B, Thon A, Fischer P, Ritzert M, Mlotok V, Piemonte C, and Zorzi N. Solid-state detector stack for ToF-PET/MR. 2009 IEEE Nucl Sci Symp Med Imaging Conf Rec. 2009:2798‑9.
- Palmowski M, Palmowski M, Hauff P, and Kiessling F. Molekulare Bildgebung in der Onkologie: Tumor-spezifische Ultraschallkontrastmittel. Praxis. 2009;98(11):597-602.
- Palmowski M, Lederle W, Bzyl J, Gaetjens J, and Kiessling F. Molecular ultrasound imaging: Principles and potential application in diagnosis and therapy monitoring of breast cancer. Eur Radiol. 2009;19 Suppl 4:S862-8.
2008
- Lammers T, Subr V, Peschke P, Kühnlein R, Hennink WE, Ulbrich K, Kiessling F, Heilmann M, Debus J, Huber PE, and Storm G. Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy. Br J Cancer. 2008;99(6):900‑10.
- Ziebart T, Yoon C, Trepels T, Wietelmann A, Braun T, Kiessling F, Stein S, Grez M, Ihling C, Muhly-Reinholz M, Carmona G, Urbich C, Zeiher AM, and Dimmeler S. Sustained persistence of transplanted proangiogenic cells contributes to neovascularization and cardiac function after ischemia. Circ Res. 2008;103(11):1327‑34.
- Kerber M, Reiss Y, Wickersheim A, Jugold M, Kiessling F, Heil M, Tchaikovski V, Waltenberger J, Shibuya M, Plate KH, and Machein MR. Flt-1 signaling in macrophages promotes glioma growth in vivo. Cancer Res. 2008;68(18):7342‑51.
- Palmowski M, Huppert J, Hauff P, Reinhardt M, Schreiner K, Socher MA, Hallscheidt P, Kauffmann GW, Semmler W, and Kiessling F. Vessel fractions in tumor xenografts depicted by flow- or contrast-sensitive three-dimensional high-frequency Doppler ultrasound respond differently to antiangiogenic treatment. Cancer Res. 2008;68(17):7042‑9.
- Kiessling F. [New contrast agents for medical MR imaging]. Z Med Phys. 2008;18(2):81.
- Kiessling F. Noninvasive cell tracking. Handb Exp Pharmacol. 2008(185 Pt 2):305‑21.
- Bäuerle T, Hilbig H, Bartling S, Kiessling F, Kersten A, Schmitt-Gräff A, Kauczor H, Delorme S, and Berger MR. Bevacizumab inhibits breast cancer-induced osteolysis, surrounding soft tissue metastasis, and angiogenesis in rats as visualized by VCT and MRI. Neoplasia. 2008;10(5):511‑20.
- Palmowski M, Hacke N, Satzl S, Klauss M, Wente MN, Neukamm M, Kleeff J, and Hallscheidt P. Metastasis to the pancreas: characterization by morphology and contrast enhancement features on CT and MRI. Pancreatology. 2008;8(2):199‑203.
- Bartling SH, Dinkel J, Stiller W, Grasruck M, Madisch I, Kauczor H, Semmler W, Gupta R, and Kiessling F. Intrinsic respiratory gating in small-animal CT. Eur Radiol. 2008;18(7):1375‑84.
- Hamzah J, Jugold M, Kiessling F, Rigby P, Manzur M, Marti HH, Rabie T, Kaden S, Gröne H, Hämmerling GJ, Arnold B, and Ganss R. Vascular normalization in Rgs5-deficient tumours promotes immune destruction. Nature. 2008;453(7193):410‑4.
- Palmowski M, Morgenstern B, Hauff P, Reinhardt M, Huppert J, Maurer M, Woenne EC, Doerk S, Ladewig G, Jenne JW, Delorme S, Grenacher L, Hallscheidt P, Kauffmann GW, Semmler W, and Kiessling F. Pharmacodynamics of streptavidin-coated cyanoacrylate microbubbles designed for molecular ultrasound imaging. Invest Radiol. 2008;43(3):162‑9.
- Hallscheidt P, Haferkamp A, Lopez-Benitez R, and Palmowski M. [Differential diagnosis of renal tumors]. Radiologe. 2008;48(3):293‑302.
- Palmowski M, Huppert J, Ladewig G, Hauff P, Reinhardt M, Mueller MM, Woenne EC, Jenne JW, Maurer M, Kauffmann GW, Semmler W, and Kiessling F. Molecular profiling of angiogenesis with targeted ultrasound imaging: early assessment of antiangiogenic therapy effects. Mol Cancer Ther. 2008;7(1):101‑9.
- Jugold M, Palmowski M, Huppert J, Woenne EC, Mueller MM, Semmler W, and Kiessling F. Volumetric high-frequency Doppler ultrasound enables the assessment of early antiangiogenic therapy effects on tumor xenografts in nude mice. Eur Radiol. 2008;18(4):753‑8.
- Lutz M, Rosenberg M, Kiessling F, Eckstein V, Heger T, Krebs J, Ho AD, Katus HA, and Frey N. Local injection of stem cell factor (SCF) improves myocardial homing of systemically delivered c-kit + bone marrow-derived stem cells. Cardiovasc Res. 2008;77(1):143‑50.
- Siepmann M, Schmitz G, Palmowski M, and Kiessling F. Statistical corrections for the precise estimation of cyanoacrylate microbubble concentration in targeted imaging. 2008 IEEE Ultrason Symp. 2008:993‑6.
Helmholtz Institute Research Reports (pdf)
Click the year to download: 2011 – 2010 – 2009 – 2008
University Hospital Research Reports (pdf, German)
Contents
- 2013 Publications (PubMed)
- 2013 Publications (IEEE Xplore)
- 2013 Publications (other)
- 2012 Publications (PubMed)
- 2012 Publications (IEEE Xplore)
- 2012 Publications (other)
- 2011 Publications (PubMed)
- 2011 Publications (IEEE Xplore)
- 2011 Publications (other)
- 2010 Publications (PubMed)
- 2010 Publications (IEEE Xplore)
- 2010 Publications (other)
- 2009 Publications (IEEE Xplore)
- 2009 Publications (PubMed)
- 2009 Publications (other)
- 2008 Publications (PubMed)
- 2008 Publications (IEEE Xplore)
- Helmholtz Institute Research Reports (pdf)
