Message archive
Why do tumor cells grow more aggressively in an acidic microenvironment?
Glioblastoma stem cells grow more aggressively in an acidic microenvironment. In our most recent publication, which was published in Pflügers Archiv – European Journal of Physiology, we show that…
Interaction of an ion channel family with neuropeptides in diverse animals
DEG/ENaC ion channels serve different functions: in some animals they detect mechanical stimuli, in others they detect pheromones, and in humans they are sensitive for acid and are important for…
Catharina Maiers receives the Friedrich Wilhelm Award of RWTH Aachen University
Today, our former MD student, Catharina Maiers (née Reimers), received the Friedrich Wilhelm Award of RWTH Aachen University. The Friedrich Wilhelm Award is awarded by the foundation of the same name…
Annual Retreat of the Institute of Physiology
Today more than 30 members of the Institute of Physiology assembled at Youth Hostel Aachen for our annual retreat. Big thanks to everyone for the great presentations and lively discussions. And for…
Shari Wiegreffe successfully finished her MD thesis
Today our MD student Shari Wiegreffe successfully passed the oral examination at the end of her thesis. Already in 2021, the results of her doctoral thesis had been published in Pflüger´s Archiv –…
Michèle Bachmann successfully finished her PhD thesis
Today our PhD student Michèle Bachmann successfully defended her dissertation entitled "Experimental approaches to mapping the binding site of RFamides on the peptide-gated Hydra magnipapillata sodium…
Interaction of opioid neuropeptides with ASIC1a resolved
Stem cells of glioblastoma, the most aggressive brain tumor, express functional Acid-Sensing Ion channel (ASIC) 1a. It was unclear, however, which role ASIC1a has for a brain tumor. In our most recent…
Catharina Maiers receives the thesis award of the Medical Faculty!
Today, our former MD student, Catharina Maiers (née Reimers), received the thesis award of the Medical Faculty donated by Grünenthal. She received the award for her thesis entitled „Identification of…
Für die Ohren: Faszination Physiologie
Worin seine Faszination für die Physiologie begründet liegt und welche Chancen das Fach für den wissenschaftlichen Nachwuchs bereithält, erklärt Univ.-Prof. Dr. Stefan Gründer, Direktor des Instituts…
Identification of a physiological role of the bile acid-sensitive ion channel BASIC in bile duct epithelial cells
The bile acid-sensitive ion channel BASIC is a close relative of the epithelial Na+ channel (ENaC) and the acid-sensing ion channels (ASICs). It is found in various tissues including liver and brain.…