Clinical pharmacogenetic research

In our clinical research projects, we investigate the reasons for the variability in drug effects in patients. Differences in response and side effects of therapies depend on individual patient characteristics, such as advanced age, comorbidities, co-medication or pharmacogenetic profiles. By exploring the variability in the effect of drugs in different patients, we also learn to understand other molecular modes of action of drugs, which in turn can lead to new targets or therapeutic strategies.