Dr. Jan-Frieder Harmsen

Pauwelsstraße 30, 52074 Aachen
Phone: +49 241 80-83261

Short biography

  • 2019 - 2023: Doctor of Philosophy (Ph.D.) in Biomedical Science, Maastricht University, The Netherlands
  • 2016 - 2019: Master of Science (MSc) in Exercise Physiology, German Sport University Cologne, Germany
  • 2012 - 2015: Bachelor of Science (BSc) in Exercise Physiology, German Sport University Cologne, Germany

Professional career
  • since 11/2023: Postdoctoral Researcher in the teaching and research area Healthy Living Spaces, University Hospital RWTH Aachen, Germany
  • since 02/2022: Host of the Science Podcast “247Muscle”: www.247muscle.com 

Research interests
  • Chronobiology: Timing of behavior, Health risks of shift work
  • Interaction of light exposure & health
  • Influence of environmental light & temperature on cardiovascular & metabolic health
  • Healthy aging
  • Exercise physiology 


Harmsen J-F, Kotte M, Habets I, et al (2023) Exercise training modifies skeletal muscle clock gene expression but not 24-hour rhythmicity in substrate metabolism of men with insulin resistance. J Physiol. https://doi.org/10.1113/JP285523

Harmsen J-F, van Weeghel M, Parsons R, et al (2022) Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men. Cell Rep 41(11):111786. https://doi.org/10.1016/j.celrep.2022.111786

Harmsen J-F, Wefers J, Doligkeit D, et al (2022) The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day. Diabetologia 65(4):721–732. https://doi.org/10.1007/s00125-021-05643-9

Harmsen J-F, van Polanen N, van Weeghel M, et al (2021) Circadian misalignment disturbs the skeletal muscle lipidome in healthy young men. FASEB J 35(6):e21611. https://doi.org/10.1096/fj.202100143R

Harmsen J-F, Latella C, Mesquita R, et al (2021) H-reflex and M-wave responses after voluntary and electrically evoked muscle cramping. Eur J Appl Physiol 121(2):659–672. https://doi.org/10.1007/s00421-020-04560-w

Franz A, Berndt F, Raabe J, Harmsen J-F, Zilkens C, Behringer M (2020) Invasive Assessment of Hemodynamic, Metabolic and Ionic Consequences During Blood Flow Restriction Training. Front Physiol 11:617668. https://doi.org/10.3389/fphys.2020.617668

Harmsen J-F, Sistig A, Fasse A, Hackl M, Wegmann K, Behringer M (2020) Neuromuscular Electrical Stimulation Reduces Leg Cramps in Patients With Lumbar Degenerative Disorders: A Randomized Placebo-Controlled Trial. Neuromodulation. https://doi.org/10.1111/ner.13315

Gutierrez-Monreal MA, Harmsen J-F, Schrauwen P, Esser KA (2020) Ticking for Metabolic Health: The Skeletal-Muscle Clocks. Obesity 28 Suppl 1:S46–S54. https://doi.org/10.1002/oby.22826

Harmsen J-F, Franz A, Mayer C, et al (2019) Tensiomyography parameters and serum biomarkers after eccentric exercise of the elbow flexors. Eur J Appl Physiol 119(2):455–464. https://doi.org/10.1007/s00421-018-4043-4

Behringer M, Harmsen J-F, Fasse A, Mester J (2018) Effects of Neuromuscular Electrical Stimulation on the Frequency of Skeletal Muscle Cramps: A Prospective Controlled Clinical Trial. Neuromodulation 21(8):815–822. https://doi.org/10.1111/ner.12728

Franz A, Joseph L, Mayer C, Harmsen J-F et al (2018) The role of oxidative and nitrosative stress in the pathology of osteoarthritis: Novel candidate biomarkers for quantification of degenerative changes in the knee joint. Orthop Rev 10(2):7460. https://doi.org/10.4081/or.2018.7460

Franz A, Behringer M, Harmsen J-F, et al (2018) Ischemic Preconditioning Blunts Muscle Damage Responses Induced by Eccentric Exercise. Med Sci Sports Exerc 50(1):109–115. https://doi.org/10.1249/MSS.0000000000001406

Mayer C, Franz A, Harmsen J-F, et al (2017) Soft-tissue damage during total knee arthroplasty: Focus on tourniquet-induced metabolic and ionic muscle impairment. J Orthop 14(3):347–353. https://doi.org/10.1016/j.jor.2017.06.015