Message archive
New insights into the gating mechanism of a species variant of the TRPM2 ion channel using the Ca2+ channel modulator 2-APB
2-Aminoethyldiphenylborinate (2-APB) is described as a modulator of both intracellular Ca2+ channels (IP3 receptor) and Ca2+ channels of the plasma membrane (Orai, TRP channels). Its effect can be…
Daniel Löhrer successfully finished his PhD thesis
Today our former PhD student Daniel Löhrer successfully defended his dissertation entitled “Proteinbiochemische und elektrophysiologische Charakterisierung des bile acid-sensitve ion channels BASIC“.…
LaborJournal berichtet über Veröffentlichung des Instituts für Physiologie
In seiner neuesten Ausgabe berichtet das LaborJournal in der Rubrik Journal Club über die letzte Veröffentlichung des Instituts für Physiologie, die in PNAS erschienen ist und die Identifizierung…
Identification of a cono-RFamide that targets ASIC3 and enhances muscle pain
“Marine cone snails provide one of the highest toxin-diversities among venomous animals, the conotoxins, which often target ion channels. In addition, cone snail venoms contain short conopeptides, the…
Paper in PNAS published
Today a paper of the institute of physiology has been published online in the renowned journal PNAS (USA). This paper reports the isolation of a short peptide from a cone snail venom, which targets…
Axel Schmidt receives Best Poster award
Today, our scientist Axel Schmidt received the Best Poster award in the session Ion Channels III at the 96th Annual Meeting of the German Physiological Society in Greifswald. His Poster was entitled…
Lisa Dautzenberg successfully finished her MD thesis
Today our MD student Lisa Dautzenberg successfully passed the oral examination at the end of her MD thesis. Her doctoral thesis is entitled „Acid-sensing ion channel (ASIC4) – Untersuchungen zur…
In praise of simple nervous systems
In an opinion article, which was published on 29 December 2016 online ahead of print in the review journal Trends in Neurosciences (Link), a group of international scientists, including Stefan Gründer…
Our former scientist Niko Joeres successfully finished his MD thesis with highest honor
Today our MD student Niko Joeres successfully passed the oral examination at the end of his MD thesis. His doctoral thesis is entitled "Functional and pharmacological characterization of two different…
Our scientist Axel Schmidt successfully finished his MD thesis with highest honor
Today our MD student Axel Schmidt successfully passed the oral examination at the end of his MD thesis. His doctoral thesis is entitled "Der Bile-Acid Sensitive Ion Channel wird über einen…
Identification of a regulatory motif of the bile acid-sensitive ion channel (BASIC)
The bile acid-sensitive ion channel BASIC is closely related to the epithelial Na+ channel (ENaC) and acid-sensing ion channels (ASICs). Its function is not understood yet. In our current study, which…
Our former scientist Katharina Friedrich successfully finished her MD thesis
Today our MD student Katharina Friedrich successfully passed the oral examination at the end of her MD thesis. Her doctoral thesis is entitled "Intrazelluläre Lokalisation und Targeting von ASIC4". We…
