The complexity of the DEG/ENaC ion channel family revealed

DEG/ENaC ion channels share a common structure but serve many different functions. What was the ancestral function of these channels? How did their diversity develop during evolution? These are the…

Why do tumor cells grow more aggressively in an acidic microenvironment?

Glioblastoma stem cells grow more aggressively in an acidic microenvironment.  In our most recent publication, which was published in Pflügers Archiv – European Journal of Physiology, we show that…

Interaction of an ion channel family with neuropeptides in diverse animals

DEG/ENaC ion channels serve different functions: in some animals they detect mechanical stimuli, in others they detect pheromones, and in humans they are sensitive for acid and are important for…

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To the calendar of events of the Uniklinik RWTH Aachen