Message archive

Today, our PhD student Sven Kuspiel successfully defended his doctoral thesis, in which he had analysed with electrophysiological methods the interaction of a new associated protein with Acid-Sensing…

Acid-sensing ion channels (ASICs) are proton-gated Na+-channels, which are normally expressed in neurons. However, also many tumour cells express ASICs. Because tumour cells thrive in an acidic…

Melatonin is well known as “sleeping hormone”. In the USA and Canada, it is also sold as an over-the-counter dietary supplement and strong antioxidative effects and positive effects on diverse…

Today, our former MD student, Jan Clusmann (on the left), received the Dissertation Award of the German Physiological Society (DPG) for his medical thesis. He received the award at the annual meeting…

Typically, the micro-environment of a tumour has a slightly acidic pH. It it therefore important to characterize acid sensors, like Acid-sensing ion channels (ASICs), in tumor cells. In our most…

Acid-sensing ion channels (ASICs) are proton-gated ion channels that are also expressed in the peripheral nervous system where they detect painful acidosis. ASICs assemble as homo- or heterotrimers.…

Phytochemicals represent a large pool of substances with the potential to modulate diverse proteins, for example ion channels. In our recent study, which has been published in the journal ACS Chemical…

Today our MD student Elinor Cleuvers successfully passed the oral examination at the end of her thesis. Part of the results of her doctoral thesis entitled „Interaction of the opioid neuropeptid Big…

Am 21.02.2023 verstarb Helmut Kammermeier, von 1971-1997 Professor am Institut für Physiologie. Bereits 1966 kam H. Kammermeier mit dem Gründungsdirektor des Instituts, Eckehard Gerlach, aus Freiburg…

Today our MD student Jan Clusmann successfully passed the oral examination at the end of his thesis with summa cum laude. The results of his doctoral thesis entitled „Acid-sensing ion channel 1a…

Today our PhD student Katharina Foreman successfully defended her dissertation entitled „Functional Ion Channel Characterization in the Cnidarian Nematostella vectensis”. We sincerely congratulate her…

DEG/ENaC ion channels share a common structure but serve many different functions. What was the ancestral function of these channels? How did their diversity develop during evolution? These are the…