Typically, the micro-environment of a tumour has a slightly acidic pH. It it therefore important to characterize acid sensors, like Acid-sensing ion channels (ASICs), in tumor cells. In our most…

Acid-sensing ion channels (ASICs) are proton-gated ion channels that are also expressed in the peripheral nervous system where they detect painful acidosis. ASICs assemble as homo- or heterotrimers.…

Today our MD student Elinor Cleuvers successfully passed the oral examination at the end of her thesis. Part of the results of her doctoral thesis entitled „Interaction of the opioid neuropeptid Big…