Message archive

At the general meeting of the German Physiological Society (DPG) at the Europhysiology meeting in London, Stefan Gründer was elected to Vice-President of the DPG. His term starts on 1st of January…

On August 1 2018, Dr. Lilia Leisle starts at the Institute of Physiology in the Gründer group. After finishing her thesis at the Max-Delbrück-Center for Molecular Medicine in Berlin, she moved for six…

RFamid-neuropeptides are important modulators of Acid-sensing ion channels (ASICs), in particular of ASIC3. By slowing desensitization of ASIC3, they strongly increase the excitatory current, which…

Voltage-gated sodium channels (Navs) not only respond to changes in membrane potential, but are also modified by mechanical stress in the cell membrane. In a living organism, mechanical influences are…

Opioids are often the last resort for pain relief in patients that suffer from severe acute or chronic pain. Unfortunately, opioids can cause addiction and they have recently become notorious for…

Neuropeptides are structurally diverse and broadly distributed in the animal kingdom. Typically, they activate G protein-coupled receptors. But we also know a few ion channels that are directly…

Acid-sensing ion channels (ASICs) are proton-gated ion channels with important physiological functions. Inhibiting ASICs has neuroprotective effects, for example during ischemic stroke. Because…

We welcome Daniel S. Barth as a new Post-Doc at the Institute of Physiology in the Lückhoff group. Dr. Barth successfully completed his Ph.D. thesis in August 2017 at the Institute of Physiology,…

The bile acid-sensitive ion channel BASIC is modulated by a variety of different amphiphilic substances, which modify the biophysical properties of the surrounding membrane. The precise mechanism…

Today, Abhilasha Ladha starts as a Post-Doc at the Institute of Physiology in the Gründer group. Originally from India, she just finished her PhD work at the Institute of Physiology at the University…

Gestern Morgen verstarb der langjährige Direktor des Instituts für Physiologie, Holger Schmid-Schönbein. H. Schmid-Schönbein leitete das Institut für fast 30 Jahre, von 1974 – 2003; von 1981 – 1983…

The human transient receptor potential melastatin type 2 (TRPM2) channel represents a critical factor in the course of oxidative stress-induced apoptosis. Therefore, it is considered as a potential…