Welcome to the Website of the Institute of Physiology!
The Institute of Physiology is one of three Physiological Institutes. Our research has a focus on ion channels. Ion channels are the basis of neuronal excitability and of communication between neurons. Mutations in ion channels can lead to diseases and malregulation of ion channels determines the clinical picture of many diseases. The analysis of ion channels in molecular detail contributes to a better understanding of their pathophysiological role and is the basis for an educated pharmacotherapy. In addition, the group of Khosrow Mottaghy works on artificial organs, in particular on extracorporeal circulation.
On our website you can find the most relevant information on us and on our research. We strive for a high quality in teaching. More information on our teaching and on the history of the Institute can be found here (in German only).
Yours sincerely
Stefan Gründer
News from the Institute of Physiology
News
Paper of the month: Preisträger Dr. Sven Kuspiel, Prof. Dr. Stefan Gründer & Dr. Dominik Wiemuth
In der Forschungsarbeit von Dr. Sven Kuspiel, Prof. Dr. Stefan Gründer, Dr. Dominik Wiemuth und ihrem Team wird untersucht, ob ein im Nervensystem vorkommender Ionenkanal Komplexe mit anderen…
Anton Richter successfully finished his MD thesis
Today our MD student Anton Richter successfully passed the oral examination at the end of his doctoral thesis, which is entitled „Investigations on the ASIC-dependent acid-induced cell death”. Anton…
Post-Doc (w/m/d) im Bereich Neuronaler Ionenkanäle gesucht
Das Institut für Physiologie an der Uniklinik RWTH Aachen besetzt eine Stelle als
Post-Doc (w/m/d) im Bereich Neuronaler Ionenkanäle
mit 100 Prozent der vollen tariflich vereinbarten Arbeitszeit…
International ASIC 2025 conference successfully held
From 29 September to 1 October 2025, the first international scientific meeting on acid-sensing ion channels took place in Tutzing on Lake Starnberg. The event was organised by Prof. Stefan Gründer,…
DPG names publication by the Institute of Physiology as ‘Paper of the Month’
The German Physiological Society has named a recent publication by the Institute of Physiology at RWTH Aachen University Hospital as ‘Paper of the Month’ for September 2025. The paper was recently…
13.09.2025 – Stefan Gründer receives the badge of honor of the German Physiological Society
At the general assembly of the German Physiological Society (DPG) during the 40th congress of the International Union of Physiological Societies (IUPS) in Frankfurt/Main, Stefan Gründer received the…
From our research
The fruit fly Drosophila melanogaster is an important model organism. It contains an ion channel family, termed PPKs, with homology to ASICs and ENaC in humans. In our last study, which was performed…
Forschende der Uniklinik RWTH Aachen identifizieren Helferprotein: PCYOX1L ist beteiligt an synaptischer Übertragung
Ein Team um Univ.-Prof. Dr. Stefan Gründer, Direktor des Instituts für Physiologie an der Uniklinik RWTH Aachen, und PD Dr. Dominik Wiemuth hat in einer neuen Publikation das Protein PCYOX1L als…
Dr. Razan El Faraj comes from the Karlsruhe Institute of Technology to work at the Institute of Physiology
On July 1st, Dr. Razan El Faraj started at the Institute of Physiology as a post-doctoral researcher. She has two M.Sc. degrees: one in Bioengineering from the Cyprus International University and one…
02.04.2025 – Dr. Samuel Kühs comes from Lübeck University to work at the Institute of Physiology
On April 1st, Dr. Samuel Kühs started at the Institute of Physiology as a post-doctoral researcher. After finishing his M.Sc. in Neurosciences at Oldenburg University, he did his Ph.D. in the group of…
Ammar Hawashin successfully finished his MD thesis with highest honors
On March 31st 2025 our MD student Ammar Hawashin successfully passed the oral examination at the end of his thesis. His doctoral thesis is entitled „Modulation of Acid-Sensing Ion Channels by Tannic…
Stefan Gründer co-organizes first scientific meeting dedicated to acid-sensing ion channels
Together with Stephan Kellenberger from the University of Lausanne, Stefan Gründer organizes the first international scientific meeting dedicated to Acid-Sensing Ion Channels – ASIC 2025. ASIC 2025…
