Publikationen

2020

Holzer G, Antonin W. (2020). FXR proteins bring new perspectives to nucleoporins' homeostasis.
EMBO Journal 39(20):e106510. doi: 10.15252/embj.2020106510.

Moreno-Andrés D, Yokoyama H, Scheufen A, Holzer G, Lue H, Schellhaus AK, Weberruss M, Takagi M, Antonin W.  (2020). VPS72/YL1-Mediated H2A.Z Deposition Is Required for Nuclear Reassembly after Mitosis. Cells 16;9(7):E1702. doi: 10.3390/cells9071702.

 
2019

Holzer G, Antonin W. (2019). Breaking the Y. PLoS Genetics 15(5):e1008109. doi: 10.1371/journal.pgen.1008109.

Zanni G, De Magistris P, Nardella M, Bellacchio E, Barresi S, Sferra A, Ciolfi A, Motta M, Lue H, Moreno-Andres D, Tartaglia M, Bertini E, Antonin W. (2019). Biallelic Variants in the Nuclear Pore Complex Protein NUP93 Are Associated with Non-progressive Congenital Ataxia. Cerebellum doi: 10.1007/s12311-019-1010-5.

Yokoyama H, Moreno-Andres D, Astrinidis SA, Hao Y, Weberruss M, Schellhaus AK, Lue H, Haramoto Y, Gruss OJ, Antonin W. (2019). Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund-Thomson syndrome. Life Science Alliance 2(1). pii: e201800120. doi: 10.26508/lsa.201800120.

 
2018

Braun DA, Lovric S, Schapiro D, Schneider R, Marquez J, Asif M, Hussain MS, Daga A, Widmeier E, Rao J, Ashraf S, Tan W, Lusk CP, Kolb A, Jobst-Schwan T, Schmidt JM, Hoogstraten CA, Eddy K, Kitzler TM, Shril S, Moawia A, Schrage K, Khayyat AIA, Lawson JA, Gee HY, Warejko JK, Hermle T, Majmundar AJ, Hugo H, Budde B, Motameny S, Altmüller J, Noegel AA, Fathy HM, Gale DP, Waseem SS, Khan A, Kerecuk L, Hashmi S, Mohebbi N, Ettenger R, Serdaroğlu E, Alhasan KA, Hashem M, Goncalves S, Ariceta G, Ubetagoyena M, Antonin W, Baig SM, Alkuraya FS, Shen Q, Xu H, Antignac C, Lifton RP, Mane S, Nürnberg P, Khokha MK, Hildebrandt F (2018). Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. The Journal of Clinical Investigations. pii: 98688. doi: 10.1172/JCI98688.

Holzer G and Antonin W (2018). Nuclear pore complexes: Global Conservation and Local Variation. Current Biology 28(11): R674–R677

De Magistris P and Antonin W (2018). The Dynamic Nature of the Nuclear Envelope. Current Biology 28(8): R487–R497

De Magistris P, Tatarek-Nossol M, Dewor M, Antonin W (2018). A self-inhibitory interaction within Nup155 and membrane binding are required for nuclear pore complex formation. Journal of Cell Science;131(1). pii: jcs208538. doi: 10.1242/jcs.208538

De Magistris P, Suluyayla R, and Antonin W. (2018). Wie die Zelle ihre Kernporen aufbaut. BIOspektrum 24: 20–22.

 

2017

Linder MI, Köhler M, Boersema P, Weberruss M, Wandke C, Marino J, Ashiono C, Picotti P, Antonin W, Kutay U (2017). Mitotic Disassembly of Nuclear Pore Complexes Involves CDK1- and PLK1-Mediated Phosphorylation of Key Interconnecting Nucleoporins. Developmental Cell 43 (2): 141–156.

Schellhaus AK, Moreno-Andrés D, Chugh M, Yokoyama H, Moschopoulou A, De S, Bono F, Hipp K, Schäffer E, Antonin W (2017). Developmentally Regulated GTP binding protein 1 (DRG1) controls microtubule dynamics. Scientific Reports. 7(1): 9996. doi: 10.1038/s41598-017-10088-5.

Silva Alves N, Astrinidis SA, Eisenhardt N, Sieverding C, Redolfi J, Lorenz M, Weberruss M, Moreno-Andrés D, Antonin W (2017). MISTIC-fusion proteins as antigens for high quality membrane protein antibodies. Scientific Reports 7:41519 | DOI: 10.1038/srep41519

 
2016

Braun DA, Sadowski CE, Kohl S, Lovric S, Astrinidis SA, Pabst WL, Gee HY, Ashraf S, Lawson JA, Shril S, Airik M, Tan W, Schapiro D, Rao J, Choi WI, Hermle T, Kemper MJ, Pohl M, Ozaltin F, Konrad M, Bogdanovic R, Büscher R, Helmchen U, Serdaroglu E, Lifton RP, Antonin W, Hildebrandt F (2016). Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome. Nature Genetics, 48 (4): 457-465.

Antonin W and Neumann H (2016). Chromosome condensation and decondensation during mitosis. Current Opinion in Cell Biology, 40:15-22.

Weberruss M and Antonin W (2016). Perforating the nuclear boundary - how nuclear pore complexes assemble. Journal of Cell Science 129 (24): 4439-4447

 

2015

Vollmer B, Lorenz M,  Moreno-Andres D, Bodenhöfer M, De Magistris P, Astrinidis SA, Schooley A, Flötenmeyer M, Leptihn S, and Antonin W (2015). Nup153 recruits the Nup107-160 complex to the inner nuclear membrane for interphasic nuclear pore complex assembly. Developmental Cell, 33 (6): 717-728.

Lorenz M, Vollmer B, Unsay JD, Klupp BG, García-Sáez AJ, Mettenleiter TC, and Antonin W (2015). A Single Herpesvirus Protein can mediate Vesicle Formation in the Nuclear Envelope. Journal of Biological Chemistry, 290 (11): 6962-6974.

Schooley A, Moreno-Andrés D, De Magistris P, Vollmer B, and Antonin W (2015).  The lysine demethylase LSD1 is required for nuclear envelope formation at the end of mitosis. Journal of Cell Science, 128 (18): 3466-3477.

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, and Beck M  (2015).  In situ structural analysis of the human nuclear pore complex. Nature, 526 (7571): 140-143.

Schellhaus, AK,  De Magistris, P, and Antonin, W (2015). Nuclear reformation at the end of mitosis. (Review) Journal of Molecular Biology, 428 (10): 1962-85

Zeev-Ben-Mordehai, T, Weberruß, M, Lorenz, M, Cheleski, J, Hellberg, T, Whittle, K, El-Omari, K, Vasishtan, D, Dent, K C, Harlos, K, Hagen, W, Klupp, BG, Antonin, W*, Mettenleiter, TC, and Grünewald, K* (2015) (* corresponding authors). Crystal structure of the herpesvirus nuclear egress complex provides insights into inner nuclear membrane remodelling. Cell Reports, 13 (12): 2645-2652.

Schellhaus, AK, Magalska, A, Schooley, A, and Antonin, W (2015). A cell free assay to study chromatin decondensation at the end of mitosis. Journal of Visual Experiments (JoVE), 106: doi: 10.3791/53407.

 

2014

Magalska, A, Schellhaus, AK, Moreno-Andres, D, Zanini, F, Schooley, A, Sachdev, R, Schwarz, H, Madlung, J, Gerken, J and Antonin, W (2014). RuvB-like ATPases function in chromatin decondensation at the end of mitosis. Developmental Cell, 31 (3): 305-318.

Eisenhardt, N, Redolfi, J and Antonin, W (2014). Interaction of Nup53 with NDC1 and Nup155 is required for nuclear pore complex assembly. Journal of Cell Science, 127 (4):908-921.

Vollmer, B and Antonin, W (2014). The diverse roles of the Nup93/Nic96 complex proteins - structural scaffolds of the nuclear pore complex with additional cellular functions. (Review). Biological Chemistry, 395 (5):515-528.

Eisenhardt, N, Schooley, A and Antonin, W (2014). Xenopus in vitro assays to analyze the function of transmembrane nucleoporins and targeting of inner nuclear membrane proteins. Methods in Cell Biology, 122:193-218.

 

2013

Antonin, W (2013). Don't get stuck in the pore. (Viewpoint). EMBO Journal, 32 (2):173-175.

 

2012

Sachdev, R, Sieverding, C, Flotenmeyer, M, and Antonin, W (2012). The C-terminal domain of Nup93 is essential for assembly of the structural backbone of nuclear pore complexes. Molecular Biology of the Cell, 23 (4):740-9.

Vollmer, B, Schooley, A, Sachdev, R, Eisenhardt, N, Schneider, AM, Sieverding, C, Madlung, J, Gerken, J, Macek, B, and Antonin, W (2012). Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO Journal, 31 (20):4072-84.

Schooley, A, Vollmer, B, and Antonin, W (2012). Building a nuclear envelope at the end of mitosis: coordinating membrane reorganization, nuclear pore complex assembly, and chromatin de-condensation. (Review). Chromosoma, 121 (6):539-54.

 

2011

Antonin, W, Ungricht, R, and Kutay, U (2011). Traversing the NPC along the pore membrane: Targeting of membrane proteins to the INM. (Review). Nucleus, 2 (2):87-92.

Laurell, E, Beck, K, Krupina, K, Theerthagiri, G, Bodenmiller, B, Horvath, P, Aebersold, R, Antonin, W, and Kutay, U (2011). Phosphorylation of Nup98 by Multiple Kinases Is Crucial for NPC Disassembly during Mitotic Entry. Cell, 144 (4):539-50.

 

2010

Theerthagiri, G, Eisenhardt, N, Schwarz, H, and Antonin, W (2010). The nucleoporin Nup188 controls passage of membrane proteins across the nuclear pore complex. Journal of Cell Biology, 189 (7):1129-42.

Yavuz, S, Santarella-Mellwig, R, Koch, B, Jaedicke, A, Mattaj, IW, and Antonin, W (2010). NLS-mediated NPC functions of the nucleoporin Pom121. FEBS letters, 584 (15):3292-3298.

 

2009

Antonin, W (2009). Nuclear envelope: membrane bending for pore formation? (Dispatch). Current Biology, 19 (10):R410-2.

 

2008

Antonin, W, Ellenberg, J, and Dultz, E (2008). Nuclear pore complex assembly through the cell cycle: Regulation and membrane organization. (Review). FEBS letters, 582 (14):2004-2016.

Galy, V, Antonin, W, Jaedicke, A, Sachse, M, Santarella, R, Haselmann, U, and Mattaj, I (2008). A role for gp210 in mitotic nuclear-envelope breakdown. Journal of Cell Science, 121:317-28.

 

2007

Franz, C, Walczak, R, Yavuz, S, Santarella, R, Gentzel, M, Askjaer, P, Galy, V, Hetzer, M, Mattaj, IW, and Antonin, W (2007). MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly. EMBO Reports, 8 (2):165-72.

 

2006

Mansfeld, J, Güttinger, S, Hawryluk-Gara, LA, Pante, N, Mall, M, Galy, V, Mühlhäusser, P, Wozniak, RW, Mattaj, IW, Kutay, U, and Antonin, W (2006). The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells. Molecular Cell, 22 (1):93-103.

Ulbert, S, Antonin, W, Platani, M, and Mattaj, IW (2006). The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology. FEBS Letters, 580 (27):6435-41.

 

2005

Antonin, W, Franz, C, Haselmann, U, Antony, C, and Mattaj, IW (2005). The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation. Molecular Cell, 17 (1):83-92.

Antonin, W and Mattaj, IW (2005). Nuclear pore complexes: round the bend? Nature Cell Biology, 7 (1):10-2.

Franz, C, Askjaer, P, Antonin, W, Iglesias, CL, Haselmann, U, Schelder, M, Marco, Ad, Wilm, M, Antony, C, and Mattaj, IW (2005). Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates. EMBO Journal, 24 (20):3519-31.