Message archive
Cholesterol depletion increases sodium currents mediated by Nav1.7
Cholesterol is a crucial component of cellular membranes. In our latest study in cooperation with Giulia Rossetti, we explored the impact of cholesterol depletion on Nav1.7, a key ion channel found…
Herzlichen Glückwunsch an Dr. med. Claudia Trinler
Wir freuen uns, Frau Dr. Claudia Trinler ganz herzlich zu ihrer erfolgreich abgeschlossenen medizinischen Promotion mit dem Titel „Characterization of a co-culture system of human induced pluripotent…
Botulinum toxin alleviates pain independently of sodium channels
Botulinum toxin is not only a very dangerous neurotoxin, but also a frequently used drug in various medical fields. Apart from its muscle relaxant effect, the toxin has recently been used more and…
New spokesperson for translational neurosciences
Prof. Angelika Lampert is the new spokesperson for the Translational Neurosciences research focus at the Faculty of Medicine at RWTH Aachen University. The head of the Institute of Neurophysiology…
Patient derived neurons express Nav1.7
We use induced pluripotent stem cells to produce nerve cells from chronic pain patients. Thereby, we focus on the voltage-gated sodium channel Nav1.7, as it has been associated with pain. In order to…
Validation of stem cell-derived sensory neurons for modelling genetic pain disorders
Stem cells, such as induced pluripotent stem cells (iPSC), can be used to generate human sensory neurons. They offer an attractive humanized model system to study pathophysiological mechanisms of…
Worldwide Sodium Channel Conference 2024
At the end of January, a unique conference took place in Grindelwald in Switzerland. For three days, over one hundred scientists from 19 countries gathered to discuss and present novel insights within…
Night of the Profs: Angelika Lampert DJs at the Apollo
On Friday, October 13, 2023, the guests at the Apollo experienced a unique night when professors from Aachen's RWTH university took over the DJ booth. Among them was Prof. Dr. med. Angelika Lampert…
Temperature can trigger pain and alters sodium channel function
Sodium channels are essential for the function of peripheral sensory nerve fibers and mutations in these channels can result in chronic pain syndromes. Pain attacks are often triggered by temperature…
Precision medicine for pain patients: Precision²Treat
Prof. Angelika Lampert from the Institute for Physiology and Priv.-Doz. Dr. med. Ralf Hausmann from the Institute for Clinical Pharmacology have successfully acquired funding for the Precision2Treat…
Children's University: Prof. Lampert explains pain
How does pain actually develop and what is it good for? Prof. Angelika Lampert addressed these and other questions at the pre-Christmas Children's University lecture on 16 December 2022 in the…
Teaching award PAULA for Prof Angelika Lampert
Prof. Angelika Lampert has received the PAULA teaching award (Award for Excellent University Teaching assigned by Aachen's medical students) in the category Best Lecture on 15.07.2022 during the…
