Centers of reference are centers that support this registry project cooperatively and can, for example, assist in the analysis of tissue samples from patients with confirmed or suspected SARS-CoV-2 infection and contribute biosamples and data. So far the following centers have joined as partners:
Prof. D. Jonigk, M.D.
Institute of Pathology, Hannover Medical School
Molecular pathology for SARS-CoV-2 detection
Prof. Dr. Peter Boor, M.D., Ph.D.
Institute of Pathology, Uniklinik RWTH Aachen
We have established a sensitive RT-PCR test for the detection of SARS-CoV-2 infections in formalin-fixed paraffin embedded tissues (FFPE). Two different probes are used to detect the viral RNAs of B-beta coronavirus (B-ßCoV) in general and the Severe Acute Respiratoy Syndrome Coronavirus 2 (SARS-CoV-2).
This is the method of choice for general, non-cell-type specific virus detection in FFPE material.
We have also established a sensitive FISH and CISH method for SARS-CoV-2 detection (sense and anti-sense RNA).
These are the methods of choice for questions regarding cell-specific virus detection in FFPE material.
Please note: In case of a SARS-CoV-2 FFPE diagnostic request, please inform our team of medical specialists: Covid.Pathologieukaachende