Arbeitsgruppe Mamma-Diagnostik

Im Mittelpunkt unserer Forschung steht die Patientin: Wir forschen, um die Diagnostik noch präziser und schonender zu machen!

Aktuelle Forschungsprojekte:

  • Systematische Evaluation neuer Biopsiemethoden
  • Evaluation des Nutzens der sonographischen Scherwellen-Elastographie
  • Evaluation neuer Techniken in der Mamma-MRT
  • Entwicklung neuer Spulen für die Mamma-MRT
  • Evaluation der dynamischen Mamma-MRT als Biomarker
Aktuelle Publikationen:

Huck LC, Truhn D, Wilpert C, Zanderigo E, Raaff V, Dethlefsen E, Bode M, Kuhl CK
Background parenchymal enhancement in contrast-enhanced MR imaging suggests systemic effects of intrauterine contraceptive devices.
In: European radiology

Mann RM, Athanasiou A, Baltzer PAT, Camps-Herrero J, Clauser P, Fallenberg EM, Forrai G, Fuchsjäger MH, Helbich TH, Killburn-Toppin F, Lesaru M, Panizza P, Pediconi F, Pijnappel RM, Pinker K, Sardanelli F, Sella T, Thomassin-Naggara I, Zackrisson S, Gilbert FJ, Kuhl CK, European Society of Breast Imaging (EUSOBI).
Breast cancer screening in women with extremely dense breasts recommendations of the European Society of Breast Imaging (EUSOBI).
In: European radiology

Wetzl M, Wenkel E, Dietzel M, Siegler L, Emons J, Dethlefsen E, Heindl F, Kuhl C, Uder M, Ohlmeyer S
Potential of spiral breast computed tomography to increase patient comfort compared to DM.
In: European journal of radiology

Kuhl CK, Baltzer P
You Get What You Pay For: Breast MRI Screening of Women With Dense Breasts Is Cost-effective.
In: Journal of the National Cancer Institute

Kuhl CK
Let Us Move Out of Plato's Cave: The Greater Reality of DCIS.
In: Radiology

Schiaffino S, Pinker K, Magni V, Cozzi A, Athanasiou A, Baltzer PAT, Camps Herrero J, Clauser P, Fallenberg EM, Forrai G, Fuchsjäger MH, Helbich TH, Kilburn-Toppin F, Kuhl CK, Lesaru M, Mann RM, Panizza P, Pediconi F, Pijnappel RM, Sella T, Thomassin-Naggara I, Zackrisson S, Gilbert FJ, Sardanelli F
Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging (EUSOBI).
In: Insights into imaging

Kuhl CK
A Call for Improved Breast Cancer Screening Strategies, Not Only for Women With Dense Breasts.
In: JAMA network open

Kuhl CK
Let Us Move Out of Plato's Cave: The Greater Reality of DCIS.
In: Radiology

Wetzl M, Wenkel E, Balbach E, Dethlefsen E, Hartmann A, Emons J, Kuhl C, Beckmann MW, Uder M, Ohlmeyer S
Detection of Microcalcifications in Spiral Breast Computed Tomography with Photon-Counting Detector Is Feasible: A Specimen Study.
In: Diagnostics (Basel, Switzerland)

Graeser M, Schrading S, Gluz O, Strobel K, Herzog C, Umutlu L, Frydrychowicz A, Rjosk-Dendorfer D, Würstlein R, Culemann R, Eulenburg C, Adams J, Nitzsche H, Prange A, Kümmel S, Grischke EM, Forstbauer H, Braun M, Potenberg J, von Schumann R, Aktas B, Kolberg-Liedtke C, Harbeck N, Kuhl CK, Nitz U
Magnetic resonance imaging and ultrasound for prediction of residual tumor size in early breast cancer within the ADAPT subtrials.
In: Breast cancer research : BCR

Graeser M, Schrading S, Gluz O, Strobel K, Würstlein R, Kümmel S, Schumacher C, Grischke EM, Forstbauer H, Braun M, Christgen M, Adams J, Nitzsche H, Just M, Fischer HH, Aktas B, Potenberg J, von Schumann R, Kolberg-Liedtke C, Harbeck N, Kuhl CK, Nitz U
Early response by MR imaging and ultrasound as predictor of pathologic complete response to 12-week neoadjuvant therapy for different early breast cancer subtypes: Combined analysis from the WSG ADAPT subtrials.
In: International journal of cancer

Zimmermann M, Kuhl CK, Engelke H, Bettermann G, Keil S
Factors That Drive Heterogeneity of Response-to-Treatment of Different Metastatic Deposits Within the Same Patients as Measured by RECIST 1.1 Analyses.
In: Academic radiology

Kuhl CK, Lehman C, Bedrosian I
Imaging in Locoregional Management of Breast Cancer.
In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Thüring J, Kuhl CK, Barabasch A, Hitpass L, Bode M, Bünting N, Bruners P, Krämer NA
Signal changes in T2-weighted MRI of liver metastases under bevacizumab-A practical imaging biomarker?
In: PloS one

Biganzoli L, Cardoso F, Beishon M, Cameron D, Cataliotti L, Coles CE, Delgado Bolton RC, Trill MD, Erdem S, Fjell M, Geiss R, Goossens M, Kuhl C, Marotti L, Naredi P, Oberst S, Palussière J, Ponti A, Rosselli Del Turco M, Rubio IT, Sapino A, Senkus-Konefka E, Skelin M, Sousa B, Saarto T, Costa A, Poortmans P
The requirements of a specialist breast centre.
In: Breast (Edinburgh, Scotland)

Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, Bergin JT, Rahbar H, Sung JS, Jacobs C, Harvey JA, Nicholson MH, Ward RC, Holt J, Prather A, Miller KD, Schnall MD, Kuhl CK
Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening.
In: JAMA

Bick U, Trimboli RM, Athanasiou A, Balleyguier C, Baltzer PAT, Bernathova M, Borbély K, Brkljacic B, Carbonaro LA, Clauser P, Cassano E, Colin C, Esen G, Evans A, Fallenberg EM, Fuchsjaeger MH, Gilbert FJ, Helbich TH, Heywang-Köbrunner SH, Herranz M, Kinkel K, Kilburn-Toppin F, Kuhl CK, Lesaru M, Lobbes MBI, Mann RM, Martincich L, Panizza P, Pediconi F, Pijnappel RM, Pinker K, Schiaffino S, Sella T, Thomassin-Naggara I, Tardivon A, Ongeval CV, Wallis MG, Zackrisson S, Forrai G, Herrero JC, Sardanelli F, European Society of Breast Imaging (EUSOBI), with language review by Europa Donna–The European Breast Cancer Coalition.
Image-guided breast biopsy and localisation: recommendations for information to women and referring physicians by the European Society of Breast Imaging.
In: Insights into imaging

Nolte T, Gross-Weege N, Doneva M, Koken P, Elevelt A, Truhn D, Kuhl C, Schulz V
Spiral blurring correction with water-fat separation for magnetic resonance fingerprinting in the breast.
In: Magnetic resonance in medicine

Bitencourt AG, Rossi Saccarelli C, Kuhl C, Morris EA
Breast cancer screening in average-risk women: towards personalized screening.
In: The British journal of radiology

Tsukada H, Tsukada J, Schrading S, Strobel K, Okamoto T, Kuhl CK
Accuracy of multi-parametric breast MR imaging for predicting pathological complete response of operable breast cancer prior to neoadjuvant systemic therapy.
In: Magnetic resonance imaging

Kuhl CK
Underdiagnosis is the main challenge in breast cancer screening.
In: The Lancet. Oncology

Kuhl CK
Predict, Then Act: Moving Toward Tailored Prevention.
In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Kuhl CK
Abbreviated Magnetic Resonance Imaging (MRI) for Breast Cancer Screening: Rationale, Concept, and Transfer to Clinical Practice.
In: Annual review of medicine

Mann RM, Kuhl CK, Moy L
Contrast-enhanced MRI for breast cancer screening.
In: Journal of magnetic resonance imaging : JMRI

Kuhl CK, Schrading S
More Is More: Semiannual Breast MRI Screening in BRCA1 Mutation Carriers.
In: Clinical cancer research : an official journal of the American Association for Cancer Research

Truhn D, Schrading S, Haarburger C, Schneider H, Merhof D, Kuhl C
Radiomic versus Convolutional Neural Networks Analysis for Classification of Contrast-enhancing Lesions at Multiparametric Breast MRI.
In: Radiology

van Beek EJR, Kuhl C, Anzai Y, Desmond P, Ehman RL, Gong Q, Gold G, Gulani V, Hall-Craggs M, Leiner T, Lim CCT, Pipe JG, Reeder S, Reinhold C, Smits M, Sodickson DK, Tempany C, Vargas HA, Wang M
Value of MRI in medicine: More than just another test?
In: Journal of magnetic resonance imaging : JMRI

Zimmermann M, Kuhl C, Keil S
Characteristic changes of the ablation zone on contrast-enhanced computed tomography after radiofrequency ablation of hepatic metastases.
In: The Indian journal of radiology & imaging

Evans A, Trimboli RM, Athanasiou A, Balleyguier C, Baltzer PA, Bick U, Camps Herrero J, Clauser P, Colin C, Cornford E, Fallenberg EM, Fuchsjaeger MH, Gilbert FJ, Helbich TH, Kinkel K, Heywang-Köbrunner SH, Kuhl CK, Mann RM, Martincich L, Panizza P, Pediconi F, Pijnappel RM, Pinker K, Zackrisson S, Forrai G, Sardanelli F, European Society of Breast Imaging (EUSOBI) , with language review by Europa Donna–The European Breast Cancer Coalition.
Breast ultrasound: recommendations for information to women and referring physicians by the European Society of Breast Imaging.
In: Insights into imaging

Barabasch A, Heinzel A, Bruners P, Kraemer NA, Kuhl CK
Diffusion-weighted MRI Is Superior to PET/CT in Predicting Survival of Patients Undergoing 90Y Radioembolization of Hepatic Metastases.
In: Radiology

Kuhl CK, Keulers A, Strobel K, Schneider H, Gaisa N, Schrading S
Not all false positive diagnoses are equal: On the prognostic implications of false-positive diagnoses made in breast MRI versus in mammography / digital tomosynthesis screening.
In: Breast cancer research : BCR

Molderings GJ, Knüchel-Clarke R, Hertfelder HJ, Kuhl C
Mast Cell Activation Syndrome Mimicking Breast Cancer: Case Report With Pathophysiologic Considerations.
In: Clinical breast cancer

Boehm-Sturm P, Haeckel A, Hauptmann R, Mueller S, Kuhl CK, Schellenberger EA
Low-Molecular-Weight Iron Chelates May Be an Alternative to Gadolinium-based Contrast Agents for T1-weighted Contrast-enhanced MR Imaging.
In: Radiology

Kuhl CK
Abbreviated breast MRI for screening women with dense breast: the EA1141 trial.
In: The British journal of radiology

Kuhl CK, Bruhn R, Krämer N, Nebelung S, Heidenreich A, Schrading S
Abbreviated Biparametric Prostate MR Imaging in Men with Elevated Prostate-specific Antigen.
In: Radiology

Barkhausen J, Kahn T, Krombach GA, Kuhl CK, Lotz J, Maintz D, Ricke J, Schönberg SO, Vogl TJ, Wacker FK, German Association of Chairmen in Academic Radiology (KLR).
White Paper: Interventional MRI: Current Status and Potential for Development Considering Economic Perspectives, Part 1: General Application.
In: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

Kuhl CK, Strobel K, Bieling H, Wardelmann E, Kuhn W, Maass N, Schrading S
Impact of Preoperative Breast MR Imaging and MR-guided Surgery on Diagnosis and Surgical Outcome of Women with Invasive Breast Cancer with and without DCIS Component.
In: Radiology

Kuhl CK, Strobel K, Bieling H, Leutner C, Schild HH, Schrading S
Supplemental Breast MR Imaging Screening of Women with Average Risk of Breast Cancer.
In: Radiology

Schrading S, Strobel K, Keulers A, Dirrichs T, Kuhl CK
Safety and Efficacy of Magnetic Resonance-Guided Vacuum-Assisted Large-Volume Breast Biopsy (MR-Guided VALB).
In: Investigative radiology

Sardanelli F, Aase HS, Álvarez M, Azavedo E, Baarslag HJ, Balleyguier C, Baltzer PA, Beslagic V, Bick U, Bogdanovic-Stojanovic D, Briediene R, Brkljacic B, Camps Herrero J, Colin C, Cornford E, Danes J, de Geer G, Esen G, Evans A, Fuchsjaeger MH, Gilbert FJ, Graf O, Hargaden G, Helbich TH, Heywang-Köbrunner SH, Ivanov V, Jónsson Á, Kuhl CK, Lisencu EC, Luczynska E, Mann RM, Marques JC, Martincich L, Mortier M, Müller-Schimpfle M, Ormandi K, Panizza P, Pediconi F, Pijnappel RM, Pinker K, Rissanen T, Rotaru N, Saguatti G, Sella T, Slobodníková J, Talk M, Taourel P, Trimboli RM, Vejborg I, Vourtsis A, Forrai G
Position paper on screening for breast cancer by the European Society of Breast Imaging (EUSOBI) and 30 national breast radiology bodies from Austria, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Israel, Lithuania, Moldova, The Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerland and Turkey.
In: European radiology

Kuhl CK
The Changing World of Breast Cancer: A Radiologist's Perspective.
In: Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses.

Kuhl C, Strobel K
Response.
In: Radiology

Debald M, Abramian A, Nemes L, Döbler M, Kaiser C, Keyver-Paik MD, Leutner C, Höller T, Braun M, Kuhl C, Kuhn W, Schild HH
Who may benefit from preoperative breast MRI? A single-center analysis of 1102 consecutive patients with primary breast cancer.
In: Breast cancer research and treatment

Loibl S, Schmidt A, Gentilini O, Kaufman B, Kuhl C, Denkert C, von Minckwitz G, Parokonnaya A, Stensheim H, Thomssen C, van Calsteren K, Poortmans P, Berveiller P, Markert UR, Amant F
Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.
In: JAMA oncology

Schrading S, Kuhl CK
Breast Cancer: Influence of Taxanes on Response Assessment with Dynamic Contrast-enhanced MR Imaging.
In: Radiology

Schild HH, Naehle CP, Wilhelm KE, Kuhl CK, Thomas D, Meyer C, Textor J, Strunk H, Willinek WA, Pieper CC
Lymphatic Interventions for Treatment of Chylothorax.
In: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

Kuhl CK
The Changing World of Breast Cancer: A Radiologist's Perspective.
In: Investigative radiology

Mann RM, Balleyguier C, Baltzer PA, Bick U, Colin C, Cornford E, Evans A, Fallenberg E, Forrai G, Fuchsjäger MH, Gilbert FJ, Helbich TH, Heywang-Köbrunner SH, Camps-Herrero J, Kuhl CK, Martincich L, Pediconi F, Panizza P, Pina LJ, Pijnappel RM, Pinker-Domenig K, Skaane P, Sardanelli F, European Society of Breast Imaging (EUSOBI), with language review by Europa Donna–The European Breast Cancer Coalition.
Breast MRI: EUSOBI recommendations for women's information.
In: European radiology

Barabasch A, Kraemer NA, Ciritsis A, Hansen NL, Lierfeld M, Heinzel A, Trautwein C, Neumann U, Kuhl CK
Diagnostic accuracy of diffusion-weighted magnetic resonance imaging versus positron emission tomography/computed tomography for early response assessment of liver metastases to Y90-radioembolization.
In: Investigative radiology

Schrading S, Distelmaier M, Dirrichs T, Detering S, Brolund L, Strobel K, Kuhl CK
Digital breast tomosynthesis-guided vacuum-assisted breast biopsy: initial experiences and comparison with prone stereotactic vacuum-assisted biopsy.
In: Radiology

Strobel K, Schrading S, Hansen NL, Barabasch A, Kuhl CK
Assessment of BI-RADS category 4 lesions detected with screening mammography and screening US: utility of MR imaging.
In: Radiology

Bei Fragen bezüglich der Forschungsprojekte oder Doktorarbeiten können Sie uns jederzeit gerne kontaktieren:

Univ.-Prof. Dr. med. Christiane Kuhl
Tel.: 0241 80-88522
ckuhlukaachende