Veröffentlichungen

Originalarbeiten und Reviews

De Lorenzi F, Hansen N, Theek B, Daware R, Motta A, Breuel S, Nasehi R, Julian Baumeister J, Schöneberg J, Stojanovic N, von Stillfried S, Vogt M, Müller-Newen G, Maurer J, Sofias AM, Lammers T,* Fischer H,* Kiessling F* (2023). Engineering mesoscopic 3D tumor models with a self-organizing vascularized matrix. Adv Mater 35:e2303196.

van Kampen KA, Olaret E, Stancu IC, Duarte Campos DF, Fischer H, Mota C, Moroni L (2023). Hypotrochoidal scaffolds for cartilage regeneration. Mater Today Bio 23:100830.  

Sahle M, Wachendörfer M, Palkowitz AL, Nasehi R, Aveic S, Fischer H (2023). A fibrin-based human multicellular gingival 3D model provides biomimicry and enables long-term in vitro studies. Macromol Biosci 23:2300162.

Seidelmann M, Davtalab R, Vogt M, Rütten S, Aveic S, Fischer H (2023). 3D in vitro bone metastasis model as a tool for pharmacological assessments. Nanotheranostics 8:1-11.

Chiu KH, Karpat M, Hahn J, Chang KY, Weber M, Wolf M, Aveic S, Fischer H (2023). Cyclic stretching promotes physiological cell orientation and extracellular matrix remodeling in a periodontal ligament 3D in vitro model. Adv Healthc Mater 12:2301422.

Ben Messaoud G, Aveic S, Wachendoerfer M, Fischer H, Richtering W (2023). 3D printable gelatin methacryloyl (GelMA)-dextran aqueous two-phase system with tunable pores structure and size enables physiological behavior of embedded cells in vitro. Small 19:2208089.

Gerardo-Nava JL, Jansen J, Günther D, Klasen L, Thiebes AL, Niessing B, Bergerbit C, Meyer AA, Linkhorst J, Barth M, Akhyari P, Stingl J, Nagel S, Stiehl T, Lampert A, Leube R, Wessling M, Santoro F, Ingebrandt S, Jockenhoevel S, Herrmann A, Fischer H, Wagner W, Schmitt RH, Kiessling F, Kramann R, De Laporte L (2023). Transformative materials to create 3D functional human tissue models in vitro in a reproducible manner. Adv Healthc Mater 12:e2301030.

Nasehi R, Aveic S, Fischer H (2023). Wall shear stress during impingement at the building platform can exceed nozzle wall shear stress in microvalve-based bioprinting. Int J Bioprint 9:743.

Nasehi R, Abdallah AT, Pantile M, Zanon C, Vogt M, Rütten S, Fischer H, Aveic S (2023). A 3D geometry orchestrates the transcriptional landscape of metastatic cells in a multicellular in vitro bone model. Mater Today Bio 19:100596.

Nasehi R, Schieren J, Grannemann C, Palkowitz AL, Babendreyer A, Schwarz N, Aveic S, Ludwig A, Leube RE, Fischer H (2023). Bioprinting-associated pulsatile hydrostatic pressure elicits a mild proinflammatory response in epi- and endothelial cells. Biomater Adv 147:213329.

Wachendörfer M, Buhl EM, Ben Messaoud G, Richtering W, Fischer H (2023). pH and thrombin concentration are decisive to synthesize stiff, stable, and open-porous fibrin-collagen hydrogel blends without chemical crosslinker Adv Healthc Mater 2203302: 1-13.

Köpf M, Nasehi R, Kreimendahl F, Jockenhövel S, Fischer H (2022). Bioprinting-associated shear stress and hydrostatic pressure affect the angiogentic potential of human umbilical vein endothelial cells. Int J Bioprint 8:606.

Wachendörfer M, Schräder P, Buhl EM, Palkowitz AL, Messaoud GB, Richtering W, Fischer H (2022). A defined heat pretreatment of gelatin enables control of hydrolytic stability, Biomater Sci 10:5552–5565.

Jentsch S, Nasehi R, Kuckelkorn C, Gundert B, Aveic S, Fischer H (2021). Multiscale 3D bioprinting by nozzle-free acoustic droplet ejection. Small Methods 5:e2000971.

Palkowitz AL, Tuna T, Bishti S, Böke F, Steinke N, Müller-Newen G, Wolfart S, Fischer H (2021). Biofunctionalization of dental abutments surfaces by crosslinked ECM proteins strongly enhances adhesion and proliferation of gingival fibroblasts. Adv Healthc Mater 10:e2100132.

Aveic S, Janßen S, Nasehi R, Seidelmann M, Vogt M, Rütten S, Fischer H (2021). 3D printed in vitro bone model for the assessment of molecular and cellular cues in metastatic neuroblastoma. Biomater Sci 9:1716-1727.

Aveic S, Craveiro RB, Wolf M, Fischer H (2021). Current trends in in vitro modeling to mimic cellular crosstalk in periodontal tissue. Adv Healthc Mater 10:e2001269.

Corallo D, Frabetti S, Candini O, Gregianin E, Dominici M, Fischer H, Aveic S (2020). Emerging neuroblastoma 3D in vitro models for pre-clinical assessments. Front Immunol 11:584214.

Lin YY, Schuphan J, Dickmeis C, Buhl EM, Commandeur U, Fischer H (2020). Attachment of ultralow amount of engineered plant viral nanoparticles to mesenchymal stem cells enhances osteogenesis and mineralization. Adv Healthc Mater 2001245:1-13.

Yang Y, Yu M, Böke F, Qin Q, Hübner R, Knust S, Grundmeier G, Fischer H, Keller A (2020). Effect of nanoscale surface topography on the adsorption of globular proteins at oxide surfaces. Appl Surf Sci 535:147671.

Oikonomidis S, Greven J, Bredow J, Eh M, Prescher A, Fischer H, Thüring J, Eysel P, Hildebrand F, Kobbe P, Scheyerer MJ, Herren C (2020). Biomechanical effects of posterior pedicle screw-based instrumentation using titanium versus carbon fiber reinforced PEEK in an osteoporotic spine human cadaver model. Clin Biomech 80:105153.

Tohidnezhad M, Kubo Y, Lichte P, Heigl T, Roch D, Barahmand Pour N, Bergmann C, Sönmez TT, Hock JVP, Fragoulis A, Gremse F, Rosenhain S, Slowik A, Bienert M, Kweider N, Wruck CJ, Jahr H, Hildebrand F, Pape HC, Neuß-Stein S, Fischer H, Pufe T (2020). Effects of strontium-doped β-tricalcium scaffold on longitudinal nuclear factor kappa-beta (NF-κB) and vascular endothelial growth factor receptor-2 (VEGFR-2) promoter activities during bone healing in critical size bone defect mice model. Int J Mol Sci 21:3208.

Gerken U, Esser F, Möhlhenrich SC, Bartella AK, Lethaus B, Hölzle F, Fischer H, Raith S, Steiner T (2020). Objective computerised assessment of residual ridge resorption in the human maxilla and maxillary sinus pneumatisation. Clin Oral Investig 24:3223–3235.

Janßen S, Gach S, Kant S, Aveic S, Rütten S, Olschok S, Reisgen U, Fischer H (2020). Enhanced osteogenic differentiation of human mesenchymal stromal cells as response to periodical micropatterned Ti6Al4V surfaces. J Biomed Mater Res Part B 108B:2218–2226.

Kniebs C, Kreimendahl F, Köpf M, Fischer H, Jockenhoevel S, Thiebes AL (2020). Influence of different cell types and sources on pre‐vascularisation in fibrin and agarose–collagen gels. Organogenesis 16:14-26.

Duarte Campos DF, Zhang S, Kreimendahl F, Köpf M, Fischer H, Vogt M, Blaeser A, Apel C, Esteves-Oliveira M (2019). Hand-held bioprinting for de novo vascular formation applicable to dental pulp regeneration. Connect Tissue Res 9:1-11.

Kubo Y, Wruck CJ, Fragoulis A, Drescher W, Pape HC, Lichte P, Fischer H, Tohidnezhad M, Hildebrand F, Pufe T, Jahr H (2019). Role of Nrf2 in fracture healing: clinical aspects of oxidative stress. Calcified Tissue Int 105:341-352.

Herren C, Quast K, Prescher A, Fischer H, Thüring J, Siewe J, Hildebrand F, Greven J, Kobbe P, Pishnamaz M (2019). Influence of additional cement augmentation on endplate stability in circumferential stabilisation of osteoporotic spine fractures. Clin Biomech 68:163-168.

Kreimendahl F, Ossenbrink S, Köpf M, Westhofen M, Schmitz-Rode T, Fischer H, Jockenhoevel S, Thiebes AL (2019). Combination of vascularization and cilia formation for three-dimensional airway tissue engineering. J Biomed Mater Res Part A 107:2053-2062.

Duarte Campos DF, Rohde M, Ross M, Anvari P, Blaeser A, Vogt M, Panfil C, Yam GHF, Mehta J, Fischer H, Walter P, Fuest M (2019). Corneal bioprinting utilizing collagen-based bioinks and primary human keratocytes. J Biomed Mater Res Part A 107:1945-1953.

Gayer C, Abert J, Bullemer M, Grom S, Jauer L, Meiners W, Pfister A, Reinauer F, Vučak M, Wissenbach K, Fischer H, Poprawe R, Schleifenbaum JH (2019). Development of a solvent-free polylactide/calcium carbonate composite for selective laser sintering of bone tissue engineering scaffolds. Mat Sci Eng C-Mater 101:660-673.

Rohr N, Nebe JB, Schmidli F, Müller P, Weber M, Fischer H, Fischer J (2019). Influence of bioactive glass-coating of zirconia implant surfaces on human osteoblast behavior in vitro. Dent Mater 35:862-870.

Aveic S, Davtalab R, Vogt M, Weber W, Buttler-Bücher P, Tonini GP, Fischer H (2019). Calcium phosphate scaffolds with defined interconnecting channel structure provide a mimetic 3D niche for bone marrow metastasized tumor cell growth. Acta Biomater 88:527-539.

Duarte Campos DF, Philip MA, Gürzing S, Melcher C, Lin YY, Schöneberg J, Blaeser A, Theek B, Fischer H, Betsch M (2019). Synchronized dual bioprinting of functional bioinks and supporting materials as a translational strategy for cartilage tissue engineering. 3D Print Addit Manuf 6:63-71.

Duarte Campos DF, Bonnin Marquez A, O’Seanain C, Fischer H, Blaeser A, Vogt M, Corallo D, Aveic S (2019). Exploring cancer cell behavior in vitro in three-dimensional multi-cellular bioprintable collagen-based hydrogels. Cancers (Basel) 11:E180.

Lauria I, Kutz TN, Böke F, Rütten S, Zander D, Fischer H (2019). Influence of nanoporous titanium niobium alloy surfaces produced via hydrogen peroxide oxidative etching on the osteogenic differentiation of human mesenchymal stromal cells. Mat Sci Eng C-Mater 98:635-648.

Lennartz A, Dohmen A, Bishti S, Fischer H, Wolfart S (2018). Retrievability of implant-supported zirconia restorations cemented on zirconia abutments. J Prosthet Dent 120:740-746.

Böke F, Labude N, Lauria I, Ernst S, Müller-Newen G, Neuss S, Fischer H (2018). Biological activation of bioinert medical high performance oxide ceramics by hydrolytically stable immobilization of c(RGDyK) and BMP-2. ACS Appl Mater Interfaces 10:38669-38680.

Betsch M, Cristian C, Lin YY, Blaeser A, Schöneberg J, Vogt M, Fischer H, Duarte Campos DF (2018). Incorporating 4D into bioprinting: real-time magnetically directed collagen fiber alignment for generating complex multilayered tissues. Adv Healthc Mater 7:e1800894.

Gayer C, Abert J, Bullemer M, Grom S, Jauer L, Meiners W, Reinauer F, Vučak M, Wissenbach K, Poprawe R, Schleifenbaum JH, Fischer H (2018). Influence of the material properties of a poly(D,L-lactide)/β-tricalcium phosphate composite on the processability by selective laser sintering. J Biomech Behav Biomed Mater 87:267-278.

Schöneberg J, Theek B, De Lorenzi F, Blaeser A, Rommel D, Kuehne AJC, Kiessling F, Fischer H (2018). Engineering biofunctional in vitro vessel models using a multilayer bioprinting technique. Sci Rep 8:10430.

Sen KS, Duarte Campos DF, Köpf M, Blaeser A, Fischer H (2018). The effect of addition of calcium phosphate particles to hydrogel based composite materials on stiffness and differentiation of mesenchymal stromal cells towards osteogenesis. Adv Healthc Mater 7:1800343.

Liu CN, Böke F, Gebhard M, Devi A, Fischer H, Keller A, Grundmeier G (2018). Ultrasound-mediated deposition and cytocompatibility of apatite-like coatings on magnesium alloys. Surf Coat Technol 345:167-176.

Höner M, Lauria I, Dabhi C, Kant S, Leube R, Fischer H (2018). Periodic microstructures on bioactive glass surfaces enhance osteogenic differentiation of human mesenchymal stromal cells and promote osteoclastogenesis in vitro. J Biomed Mater Res Part A 106A:1965–1978.

Höner M, Böke F, Weber M, Fischer H (2018). Mimicking physiological flow conditions to study the degradation behaviour of bioactive glass surfaces in vitro. J Biomed Mater Res Part B 106B:228–236.

Goetzke R, Franzen J, Ostrowska A, Vogt A, Blaeser A, Klein G, Rath B, Fischer H, Zenke M, Wagner W (2018). Does soft really matter? Differentiation of induced pluripotent stem cells into mesenchymal stromal cells is not influenced by soft hydrogels. Biomaterials 22:147-158.

Lauria I, Höner M, Kant S, Davtalab R, Weik T, Sternberg K, Fischer H (2018). Response of umbilical cord mesenchymal stromal cells to varying titanium topographical signals. J Biomed Mater Res Part A 106A:180–191.

Varga V, Raith S, Loberg C, Modabber A, Bartella A, Hölzle F, Fischer H, Steiner T (2017). Classification of the level of mandibular atrophy – A computer-assisted study based on 500 CT scans. J Craniomaxillofac Surg 45:2061-2067.

Lauria I, Dickmeis C, Röder J, Beckers M, Rütten S, Lin YY, Commandeur U, Fischer H (2017). Engineered Potato virus X nanoparticles support hydroxyapatite nucleation for improved bone tissue replacement. Acta Biomater 62:317-327.

Stratesteffen H, Köpf M, Kreimendahl F, Jockenhoevel S, Fischer H (2017). GelMA-collagen blends enable drop-on-demand 3D printablility and promote angiogenesis. Biofabrication 9:045002.

Kreimendahl F, Köpf M, Thiebes AL, Duarte Campos DF, Blaeser A, Schmitz-Rode T, Apel C, Jockenhövel S, Fischer H (2017). 3D-printing and angiogenesis: Tailored agarose-type I collagen blends comprise 3D printability and angiogenesis potential for tissue engineered substitutes. Tissue Eng Part C Methods 23:604-615.

Nebelung S, Post M, Raith S, Fischer H, Knobe M, Braun B, Prescher A, Tingart M, Thüring J, Bruners P, Jahr H, Kuhl C, Truhn S (2017). Functional in-situ assessment of human articular cartilage using MRI: A whole-knee joint loading device. Biomech Model Mechanobiol 16:1971-1986.

Forget A, Blaeser A, Miessmer F, Köpf M, Duarte Campos DF, Voelcker NH, Blencowe A, Fischer H, Shastri VP (2017). Mechanically tunable bioink for 3D bioprinting of human cells. Adv Healthc Mater 6:1700255.

Esteves-Oliveira M, Wollgarten S, Liebegall S, Jansen P, Bilandzic M, Meyer-Lueckel H, Fischer H, Stollenwerk J, Poprawe R (2017). A new laser processing strategy for improving enamel erosion resistance. J Dent Res 96:1168-1175.

Bilandzic M, Wollgarten S, Stollenwerk J, Poprawe R, Esteves-Oliveira M, Fischer H (2017). Glass-ceramic coating material for the CO2 laser based sintering of thin films as caries and erosion protection. Dent Mater 33:995-1003.

Henning LM, Zavareh S, Kamm PH, Schmidt F, Höner M, Fischer H, Banhart J, Gurlo A (2017). Manufacturing and characterization of highly porous bioactive glass composite scaffolds using unidirectional freeze casting. Adv Eng Mater 19:1700129.

Blaeser A, Duarte Campos DF, Fischer H (2017). 3D bioprinting of cell-laden hydrogels for advanced tissue engineering. Curr Opin Biomed Eng 2:58-66.

Steiner T, Raith S, Steegmann J, Fischer H, Hölzle F (2017). Moderne Gesichtsprotektionsmasken im Profi-Ballsport - eine Fallstudie. Deutsche Zeitschrift für Sportmedizin 68:20-23.

Raith S, Vogel EP, Anees N, Keul C, Güth JF, Edelhoff D, Fischer H (2017). Artificial neural networks as a powerful numerical tool to classify specific features of a tooth based on 3D scan data. Comput Biol Med 80:65-76.

Smeets R, Barbeck M, Hanken H, Fischer H, Lindner M, Heiland M, Wöltje M, Ghanaati S, Kolk A (2017). Selective laser-melted fully biodegradable scaffold composed of poly(d,l-lactide) and β-tricalcium phosphate with potential as a biodegradable implant for complex maxillofacial reconstruction: In vitro and in vivo results. J Biomed Mater Res B 105:1216-1231.

Lohmann P, Willuweit A, Neffe AT, Geisler S, Gebauer TP, Beer S, Coenen HH, Fischer H, Hermanns-Sachweh B, Lendlein A, Shah NJ, Kiessling F, Langen KJ (2017). Bone regeneration induced by a 3D architectured hydrogel in a rat critical-size calvarial defect. Biomaterials 113:158-169.

Nebelung S, Sondern B, Oehrl S, Raith S, Rath B, Tingart M, Pufe T, Fischer H, Kuhl C, Jahr H, Truhn D (2017). Functional MR imaging mapping of human articular cartilage response to loading. Radiology 282:464-474.

Raith S, Wolff S, Steiner T, Hölzle F, Fischer H (2017). Planning of mandibular reconstructions based on statistical shape models. Int J Comp Assist Radiol Surg 12:99-112.

Pföss B, Höner M, Wirth M, Bührig-Polaczek A, Fischer H, Conradt R (2016). Structuring of bioactive glass surfaces at the micrometer scale by direct casting intended to influence cell response. Biomed Glasses 2:63-71.

Lauria I, Kramer M, Schröder T, Kant S, Hausmann A, Böke F, Leube R, Telle R, Fischer H (2016). Inkjet printed periodical micropatterns made of inert alumina ceramics induce contact guidance and stimulate osteogenic differentiation of mesenchymal stromal cells. Acta Biomater 44:85-96.

Blaeser A, Million N, Duarte Campos DF, Gamrad L, Barcikowski S, Fischer H (2016). Laser-based in situ embedding of metal nanoparticles into alginate hydrogels for enhanced endothelial cell adhesion. Nano Res 9:3407–3427.

Arslan E, Nellesen T, Bayer A, Prescher A, Lippross S; Nebelung S, Jahr H, Jaeger C; Huebner WD, Fischer H, Stoffel M, Shakibaei M, Pufe T, Tohidnezhad M (2016). Effect of platelet mediator concentrate (PMC) on achilles tenocytes: an in vitro study. BMC Musculoskelet Disord 17:307.

Böke F, Giner I, Keller A, Grundmeier G, Fischer H (2016). Plasma-enhanced chemical vapor deposition (PE-CVD) yields better hydrolytical stability of biocompatible SiOx thin films on implant alumina ceramics compared to rapid thermal evaporation physical vapor deposition (PVD). ACS Appl Mater Interfaces 8:17805-17816.

Raith S, Varga V, Steiner T, Hölzle F, Fischer H (2016). Computational geometry assessment for morphometric analysis of the mandible. Comp Methods Biomech Biomed Eng 7:1-8.

Köpf MJ, Duarte Campos DF, Blaeser A, Sen KS, Fischer H (2016). A tailored three-dimensionally printable agarose-collagen I blend allows encapsulation, spreading and attachment of human umbilical artery smooth muscle cells. Biofabrication 8:025011.

Duarte Campos DF, Blaeser A, Buellesbach K, Sen KS, Xun W, Tillmann W, Fischer H (2016). Bioprinting organotypic hydrogels with improved mesenchymal stem cell remodeling and mineralization properties for bone tissue engineering. Adv Healthc Mater 5:1336-1345.

Torres-Rendon JG, Köpf M, Gehlen D, Blaeser A, Fischer H, De Laporte L, Walther A (2016). Cellulose nanofibril hydrogel tubes as sacrificial templates for freestanding tubular cell constructs. Biomacromolecules 17:905-913.

Ventura Ferreira MS, Bergmann C, Bodensiek I, Peukert K, Abert J, Kramann R, Kachel P, Rath B, Rütten S, Knuchel R, Ebert BL, Fischer H, Brümmendorf TH, Schneider RK (2016). An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites. J Hematol Oncol 9:4.

Blaeser A, Duarte Campos DF, Puster U, Richtering W, Stevens MM, Fischer H (2016). Controlling shear stress in 3D-bioprinting is a key factor to balance printing resolution and stem cell integrity. Adv Healthc Mater 5:326-333.

Abert J, Amella A, Weigelt S, Fischer H (2016). Degradation and swelling issues of poly-(D,L-lactide)/β-tricalcium phosphate/calcium carbonate composites for bone replacement. J Mech Behav Biomed 54:82-92.

Birkholz MN, Agrawal G, Bergmann C, Schröder R, Lechner SJ, Pich A, Fischer H (2016). Calcium phosphate/microgel composites for 3D powderbed printing of ceramic materials. Biomed Tech 61:267-279.

Tack L, Schickle K, Böke F, Fischer H (2015). Immobilization of specific proteins to the surface of titanium dental implants using self-assembled monolayer technique. Dent Mater 31:1169–1179.

Wittenbrink I, Hausmann A, Schickle K, Lauria I, Davtalab R, Foss M, Keller A, Fischer H (2015). Low-aspect ratio nanopatterns on bioinert alumina influence the response and morphology of osteoblast-like cells. Biomaterials 62:58-65.

Neuss S, Panfil C, Duarte Campos DF, Weber M, Otten C, Reisgen U, Fischer H (2015). Adhesion of human mesenchymal stem cells can be controlled by electron beam-microstructured titanium alloy surfaces during osteogenic differentiation. Biomed Tech 60:215-223.

Kirsten A, Hausmann A, Weber M, Fischer J, Fischer H (2015). Bioactive and thermally compatible glass coating on zirconia dental implants. J Dent Res 94:297-303.

Duarte Campos DF, Blaeser A, Korsten A, Neuss S, Jäkel J, Vogt M, Fischer H (2015). The stiffness and structure of 3D printed hydrogels direct the differentiation of mesenchymal stromal cells towards adipogenic and osteogenic lineages. Tissue Eng Part A 21:740-756.

Lichte P, Kobbe P, Pfeifer R, Campbell G, Beckmann R, Tohidnezhad M, Bergmann C, Kadyrov M, Fischer H, Glüer CC, Hildebrand F, Pape HC, Pufe T (2015). Impaired fracture healing after hemorrhagic shock. Mediators Inflamm 2015;2015:132451.

Schickle K, Gerardo-Nava JL, Puidokas S, Samadian Anavar S, Bergmann C, Gingter P, Schickle B, Bobzin K, Fischer H (2015). Preparation of spherical calcium phosphate granulates suitable for the biofunctionalization of active brazed titanium alloy coatings. Biomed Tech 60:105-114

Blaeser A, Duarte Campos DF, Köpf M, Weber M, Fischer H (2014). Assembly of thin-walled, cell-laden hydrogel conduits inflated with perfluorocarbon. RSC Adv 4:46460–46469.

Bobzin K, Kopp N, Wiesner S, Puidokas S, Samadian Anavar S, Fischer H, Korsten A, Schickle K (2014). Investigation of a bioactive Ti–Co-based brazing coating on oxide high-performance ceramics in medical technology. Materialwiss Werkst 45:504-511.

Böke F, Schickle K, Fischer H (2014). Biological activation of inert ceramics: Recent advances using tailored self-assembled monolayers on implant ceramic surfaces. Materials 7:4473-4492.

Abert J, Bergmann C, Fischer H (2014). Wet chemical synthesis of strontium-substituted hydroxyapatite and its influence on the mechanical and biological properties. Ceram Int 40:9195-9203.

Bergmann CJD, Odekerken JCE, Welting TJM, Jungwirth F, Devine D, Bouré L, Zeiter S, van Rhijn LW, Telle R, Fischer H, Emans PJ (2014). Calcium phosphate based three-dimensional cold plotted bone scaffolds for critical size bone defects. Biomed Res Int 852610:1-10.

Bermann C, Schwenke A, Sajti L, Chichkov B, Fischer H (2014). Temperature-dependent morphology changes of noble metal tricalcium phosphate-nanocomposites. Ceram Int 40:7931–7939.

Kirsten A, Parkot D, Raith S, Fischer H (2014). A cusp supporting framework design can decrease critical stresses in veneered molar crowns. Dent Mater 30:321-326.

Duarte Campos DF, Vogt M, Lindner M, Kirsten A, Weber M, Megens RTA, Pyta J, Zenke M, van Zandvoort M, Fischer H (2014). Two-photon laser scanning microscopy as a useful tool for imaging and evaluating macrophage-, IL-4 activated macrophage- and osteoclast-based in vitro degradation of beta-tricalcium phosphate bone substitute material. Microsc Res Tech 77:143-152.

Lindner M, Bergmann C, Telle R, Fischer H (2013). Calcium phosphate scaffolds mimicking the gradient architecture of native long bones. J Biomed Mater Res Part A A:1-8.

Plewinski M, Schickle K, Lindner M, Kirsten A, Weber W, Fischer H (2013). The effect of crystallization of bioactive bioglass 45S5 on apatite formation and degradation. Dent Mater 29:1256–1264.

Blaeser A, Duarte Campos DF, Weber M, Neuss-Stein S, Theek B, Fischer H, Jahnen-Dechent W (2013). Biofabrication under fluorocarbon: a novel freeform fabrication technique to generate high aspect ratio tissue engineered constructs. Biores Open Access 2:374-384.

Schickle K, Korsten A, Weber M, Bergmann, C, Neuss S, Fischer H (2013). Towards osseointegration of bioinert ceramics: Can biological agents be immobilized on alumina substrates using self-assembled monolayer technique? J Eur Ceram Soc 33:2705–2713.

Lindner M, Schickle K, Bergmann C, Fischer H (2013). Ensuring defined porosity and pore size using ammonium hydrogen carbonate as porosification agent for calcium phosphate scaffolds. BioNanoMaterials14:101-108.

Duarte Campos DF, Blaeser A, Weber M, Jäkel J, Neuss S, Jahnen-Dechent W, Fischer H (2013). Three-dimensional printing of stem cell-laden hydrogels submerged in a hydrophobic high-density fluid. Biofabrication 5:015003.

Yung FY, Gutknecht N, Franzen R, Fischer H (2013). Shear strength of composite bonded to Er:YAG laser-prepared enamel: an in vitro comparative study. Lasers Med Sci 28:879-889.

Lautensack J, Rack A, Redenbach C, Zabler S, Fischer H, Gräber HG (2012). In situ demineralisation of human enamel studied by synchrotron-based X-ray microto-mography - A pilot-study. Micron 44:404-409.

Parkot D, Kirsten A, Möllers K, Pätzold W, Fischer H (2012). Simulation des Einflus-ses von Gerüstgeometrie und Okklusion auf die Lebensdauer vollkeramischer Restaurationen. Dtsch Zahnärztl Z 67:510-516.

Duarte Campos DF, Drescher W, Rath B, Tingart M, Fischer H (2012). Supporting biomaterials for articular cartilage repair. Cartilage 3:205-221.

Schickle K, Kaufmann R, Duarte Campos DF, Weber M, Fischer H (2012). Towards osseointegration of bioinert ceramics: Introducing functional groups to alumina surface by tailored self assembled monolayer technique. J Eur Ceram Soc 32:3063-3071.
Diese Originalarbeit erhielt den JECS Best Paper Award 2013. Mit diesem Preis wird die beste Publikation der letzten zwei Jahre des Journal of the European Ceramic Society ausgezeichnet.

Möllers K, Güth JF, Kirsten A, Edelhoff D, Fischer H (2012). Influence of tooth mobility on critical stresses in all-ceramic inlay-retained fixed dental prostheses: a finite element study. Dent Mater 28:146--151.

Möllers K, Pätzold W, Parkot D, Kirsten A, Güth JF, Edelhoff D, Fischer H (2011). Influence of connector design and material composition on the stress distribution of all-ceramic fixed dental prostheses: a finite element study. Dent Mater 27:e171-e175.

Lichte P, Pape HC, Pufe T, Kobbe P, Fischer H (2011). Scaffolds for bone healing: concepts, materials and evidence. Injury 42:569-573.

Schickle K, Zurlinden K, Bergmann C, Lindner M, Kirsten A, Laub M, Telle R, Jennissen H, Fischer H (2011). Synthesis of a novel tricalcium phosphate-bioactive glass composite and rhBMP-2 binding properties. J Mater Sci Mater Med 22:763--771.

Albrecht T, Kirsten A, Kappert HF, Fischer H (2011). Fracture load of different crown systems on zirconia implant abutments. Dent Mater 27:298-303.

Lindner M, Hoeges S, Meiners W, Wissenbach K, Smeets R, Telle R, Poprawe R, Fischer H (2011). Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique. J Biomed Mater Res (Part A) 97:466-471.

Zhang W, Titze M, Cappi B, Wirtz DC, Telle R, Fischer H (2010). Improved mechani­cal long-term reliability of hip resurfacing prostheses by using silicon nitride. J Mater Sci:Mater Med 21:3049-3057.

Kirsten A, Begand S, Oberbach T, Telle R, Fischer H (2010). Subcritical crack growth behavior of dispersion oxide ceramics. J Biomed Mater Res (Part B) 95B:202--206.

Bergmann C, Lindner M, Zhang W, Koczur K, Kirsten A, Telle R, Fischer H (2010). 3D-printing of bone substitute implants using calcium phosphate and bioactive glasses. J Eur Ceram Soc 30:2563-2567.

Cappi B, Neuss S, Salber J, Telle R, Knüchel R, Fischer H (2010). Cytocompatibility of high strength non-oxide ceramics. J Biomed Mater Res (Part A) 93: 67-76.

Ebert J, Özkol E, Zeichner A, Uibel K, Weiss Ö, Koops U, Telle R, Fischer H (2009). Direct inkjet printing of dental prostheses made of zirconia. J Dent Res 88:673-676.

Wätjen AM, Polsakiewicz DA, Kuhl I, Ebert J, Telle R, Fischer H (2009). Slurry deposition by airbrush for selective laser sintering of ceramic components. J Eur Ceram Soc 29:1-6.

Fischer H, De Souza RA, Wätjen AM, Richter S, Edehoff D, Mayer J, Martin M, Telle R (2008). Chemical strengthening of a dental lithium disilicate glass-ceramic material. J Biomed Mater Res (Part A) 87:582-587.

Fischer H, Waindich A, Telle R (2008). Influence of preparation of ceramic SEVNB specimens on fracture toughness testing results. Dent Mater 24:618-622.

Karl M, Fischer H, Graef F, Wichmann MG, Taylor TD, Heckmann SM (2008). Structural changes in ceramic veneered three-unit implant-supported restorations as a consequence of static and dynamic loading. Dent Mater 24:464-470.

Fischer H, Weiß R, Telle R (2008). Crack healing in alumina bioceramics. Dent Mater 24:328-332.

Kaltenborn N, Sax M, Müller FA, Müller L, Dieker H, Kaiser A, Telle R, Fischer H (2007). Coupling of phosphates on alumina surfaces for bioactivation. J Am Ceram Soc 90:1644-1646.

Fischer H, Luk M, Oedekoven B, Telle R, Mottaghy K (2007). Hemocompatibility of high strength oxide ceramic materials: An in vitro study. J Biomed Mater Res 81A: 982-986.

Fischer H, Wilkes J, Bergmann C, Kuhl I, Meiners W, Wissenbach K, Poprawe R, Telle R (2006). Bone substitute implants made of TCP/glass composites using selective laser melting technique. cfi/Ber DKG 83:57-60.

Mielczarek A, Fischer H, Riehemann W (2006). Amplitude-dependent damping of PSZ with sinter defects. Mat Sci Eng A-Struct 442:488-491.

Fischer H, Niedhart C, Kaltenborn N, Prange A, Marx R, Niethard FU, Telle R (2005). Bioactivation of inert alumina ceramics by hydroxylation. Biomaterials 26:6151-6157.

Fischer H, Hemelik M, Telle R, Marx R (2005). Influence of annealing temperature on the strength of dental glass ceramic materials. Dent Mater 21:671-677.

Fischer H, Brehme M, Telle R, Marx R (2005). Effect of ion exchange of glazed dental glass ceramics on strength parameters. J Biomed Mater Res 72A:175-179.

On HS, Edelhoff D, Fischer H (2004). Vollkeramische Brückensysteme - Möglichkeiten und Grenzen. Quintessenz Team-Journal 34:435-441.

Fischer H, Weber M, Eck M, Erdrich A, Marx R (2004). Finite element and experimental analyses of polymer based dental bridges reinforced by ceramic bars. J Biomech 37:289-294.

Fischer H, Schäfer M, Marx R (2003). Effect of surface roughness on flexural strength of veneer ceramics. J Dent Res 82:971-974.

Yildirim M, Fischer H, Marx R, Edelhoff D (2003). In vivo fracture resistance of implant-supported all-ceramic restorations. J Prosthet Dent 90:325-331.

Fischer H, Marx R (2003). Suppression of subcritical crack growth in a leucite reinforced dental glass by ion-exchange. J Biomed Mater Res 66A:885-889.

Wirtz DC, Fischer H, Neuss M, Ammenwerth J, Niethard FU, Marx R (2003). Eine neue Beschichtungsmethode für zementierte Femurschaftimplantate - Biokompatibilität, Sterilisierbarkeit und Verbundfestigkeit. Biomed Tech 48:154-161.

Fischer H, Weber M, Marx R (2003). Lifetime prediction of all-ceramic bridges by computational methods. J Dent Res 82:238-242.

Fischer H, Rentzsch W, Marx R (2002). Elimination of low-quality ceramic posts by proof testing. Dent Mater 18:570-575.

Fischer H, Rentzsch W, Marx R (2002). R-curve behavior of dental ceramic materials. J Dent Res 81:547-551.

Fischer H, Rentzsch W, Marx R (2002). A modified size effect model for brittle nonmetallic materials. Eng Fract Mech 69:781-791.

Fischer H, Marx R (2002). Fracture toughness of dental ceramics: comparison of bending and indentation method. Dent Mater 18:12-19.

Fischer H, Karaca F, Marx R (2002). Detection of microscopic cracks in dental ceramic materials by fluorescent penetrant method. J Biomed Mater Res 61:153-158.

Fischer H, Wirtz DC, Weber M, Neuss M, Niethard FU, Marx R (2001). Improvement of the long-term adhesive strength between metal stem and PMMA bone cement by a silica/silane interlayer system. J Biomed Mater Res 57:413-418.

Fischer H, Marx R (2001). Improvement of strength parameters of a leucite reinforced glass ceramic by dual ion-exchange. J Dent Res 80:336-339.

Fischer H, Dautzenberg G, Marx R (2001). Nondestructive estimation of the strength of dental ceramic materials. Dent Mater 17:289-295.

Marx R, Fischer H, Weber M, Jungwirth F (2001). Rissparameter und Weibullmodule: unterkritisches Risswachstum und Langzeitfestigkeit vollkeramischer Materialien. Dtsch Zahnärztl Z 56:90-98.

Tinschert J, Natt G, Jorewitz A, Fischer H, Spiekermann H, Marx R (2000). Belastbarkeit vollkeramischer Seitenzahnbrücken aus neuen Hartkernkeramiken. Dtsch Zahnärztl Z 55:610-616.

Fischer H, Gröbel J, Marx R (2000). Fraktographische Schadensanalyse an Dentalkeramik. Dtsch Zahnärztl Z 55:667-670.

Fischer H, Marx R (2000). Festigkeit von Dentalkeramik. ZWR 109:5-9.

Fischer H, Maier HR, Marx R (2000). Improved reability of leucite reinforced glass by ion exchange. Dent Mater 16:120-128.

Tinschert J, Natt G, Doose B, Fischer H, Marx R (1999). Seitenzahnbrücken aus hochfester Strukturkeramik. Dtsch Zahnärztl Z 54:545-550.

Tinschert J, Schimmang A, Fischer H, Marx R (1999). Belastbarkeit von zirkonoxidverstärkter In-Ceram Alumina-Keramik. Dtsch Zahnärztl Z 54:695-699.

Wirtz DC, Fischer H, Zilkens KW, Niethard FU, Marx, R. (1999). Optimierung des Knochenzement-Implantat-Verbundes durch die hydrolysebeständige Konditionierung der Metalloberfläche. Z Orthop Grenzgeb 137:447-451.

Buchbeiträge

Lindner M, Koczur K, Kirsten A, Oliveira A, Seifert G, Gemming S, Zurlinden K, Meißner M, Jennissen HP, Müller-Mai C, Fischer H (2009). Functionalized mineral surfaces: Sorption mechanisms of growth-stimulating proteins on surfaces of bone substitutes based on calcium phosphates: First status report. In:Mineral surfaces - from atomic processes to industrial application. Proceedings of First Status Seminar, Bayreuth, 10.-11.11.2009.

Fischer H, Seifert G, Gemming S, Jennissen H, Müller-Mai C (2008). Functionalized mineral surfaces: Sorption mechanisms of growth-stimulating proteins on surfaces of bone substitutes based on calcium phosphates. In: Stroink L (ed.), Mineral surfaces - from atomic processes to industrial application. Postdam: Koordinierungsbüro Geotechnologien, ISSN 1619-7399. pp. 108-116.

Höges S, Lindner M, Fischer H, Meiners W, Wissenbach K (2008). Manufacturing of bone substitute implants using selective laser melting. Proceedings of the 4th European Congress of the International Federation for Medical and Biological Engineering (IFMBE). Antwerpen, 24.-27.11.2008.

Fischer H, Telle R (2008). Future perspectives for bioceramics. In: Bellosi A, Babini GN (eds.), Global roadmap for ceramics. Proceedings of the 2nd International Congress on Ceramics. Faenza: ISTEC-CNR (ISBN: 978-88-8080-084-2). pp. 561-570.

Ebert J, Özkol E, Telle R, Fischer H, Uibel K (2008). Direct inkjet printing: a versatile method of complex shape manufacturing. In: Heinrich JG, Aneziris C (Hrsg.), Proceedings of the 10th International Conference of the European Ceramic Society. Göller Verlag, Baden-Baden, pp. 466-469.

Fischer H, Telle R (2008). Novel approaches to ceramic bone substitute implants and dental restorations. In: Heinrich JG, Aneziris C (Hrsg.), Proceedings of the 10th International Conference of the European Ceramic Society. Göller Verlag, Baden-Baden, pp. 1035-1038.

Cappi B, Salber J, Fischer H, Telle R, Kriegesmann J (2007). Mechanische und biologische Charakterisierung von Hochleistungskeramiken für die orthopädische Implantologie. In: Kriegesmann J (Hrsg.), Technische Keramische Werkstoffe, Losebl.-Ausg. Fachverlag Deutscher Wirtschaftsdienst, Köln.

Salmang H, Scholze H (2007). Keramik. 7., vollständig neubearbeitete und erweiterte Auflage. Telle R (Hrsg.). Springer-Verlag, Berlin. Fischer H: Verfasser des Kapitels 10.4 Biokeramik.

Ludwig K, Hrsg. (2005). Lexikon der Zahnmedizinischen Werkstoffkunde. Berlin: Quintessenz-Verlag. Fischer H: Umfangreiche Beiträge zu den Themengebieten dentalkeramische Werkstoffe, Bruchmechanik und Bruchstatistik.

Fischer H, Wirtz DC, Niethard FU, Marx R. Steigerung der Langzeit-Haftfestigkeit zwischen metallischem Hüftendoprothesenschaft und PMMA-Knochenzement unter physiologischen Umgebungsbedingungen. In: Implantologie: Mechanische und klinische Aspekte von Implantaten. Eifler D (Hrsg.), DVM Berlin 2000, pp. 117-125.

Marx R, Tinschert J, Fischer H. Subcritical crack growth of dental ceramic materials. In: Stallforth H, Revell P (eds.), Materials for Medical Engineering, EUROMAT, Vol. 2. Wiley-VCH, Weinheim 2000, pp. 116-119.

Fischer H, Wirtz DC, Özgören AE, Zilkens KW, Niethard FU, Marx R. Improvement of the bonding between metal implant and bone cement in total joint replacement. In: Stallforth H, Revell P (eds.), Materials for Medical Engineering, EUROMAT, Vol. 2. Wiley-VCH, Weinheim 2000, pp. 36-40.

Fischer H, Gröbel J, Marx R. Fraktographische Analyse von Dentalkeramik. In: Schneider G, Mücklich F (Hrsg.), Fortschritte in der Metallographie. Werkstoff-Informationsgesellschaft mbH, Frankfurt 2000, pp. 299-304.

Edelhoff D, Fischer H. Keramische Wurzelstiftsysteme. In: Innovative Verfahren in der Zahnheilkunde. Pröbster, L (Hrsg.), 5. Aufl., Kap. 18. Springer, Heidelberg 1999, pp. 1-53.