Message archive

New insights into the species-specific activation mechanism of the apoptosis channel TRPM2

The complex activation mechanism of the apoptosis channel TRPM2 seems to have changed significantly in the course of metazoan evolution. This special feature which has been discovered by our team a...

Projekt Bio²Treat – Neue Forschungsansätze für chronische Schmerzpatienten

Grünenthal und die Uniklinik RWTH Aachen geben heute bekannt, dass sie eine Forschungskooperation eingegangen sind, um neue Behandlungsansätze für Patienten mit neuropathischen Schmerzen zu...

Katastrophenerstversorgung: Institut für Physiologie der Uniklinik RWTH Aachen organisiert internationale Konferenz

In Zusammenarbeit mit dem Regional Centre for Science and Technology Transfer der Indian Ocean Rim Association (IORA-RCSTT) organisiert Prof. Dr. Khosrow Mottaghy vom Institut für Physiologie an...

Annual Retreat of the Institute of Physiology

Today more than 40 members of the Institute of Physiology assembled at Youth Hostel Aachen for our annual retreat. Exciting presentations and lively discussions – but also the table tennis tournament...

Newly discovered effects of bile acids on P2X receptors

In addition to their classical role in digestion, bile acids have been shown in recent years to have additional functions, particularly in various cellular signaling cascades. Recently we were able to...

Chronic pain: pioneering research on the molecular basis of pain sensation published in the international journal PAIN

Neuropathic pain syndromes are caused by a genetic modification that affects peripheral nerve fibres. Therapy of these syndromes is challenging as treatment is often unsatisfactory. Mutations of the...

First functional characterization of a novel ADPR-interaction site in TRPM2 channels

Recent cryo-electron microscopic analyzes of a species variant of the human TRPM2 channel confirm the existence of a novel interaction site for ADP-ribose (ADPR) as already postulated by our group in...

Two prizes at the 7th Symposium of the Young Physiologists in Nuremberg

At the 7th Symposium of the Young Physiologists, which took place on 14 and 15 March 2019 in Nuremberg, Germany, Sarah Thull won the prize for the best talk. The title of her talk was “Resurgent-like...

Gelungenes Forschungsprojekt

Forschungsprojekt des Instituts für Physiologie wird vom Bundesministerium für Wirtschaft und Energie als Erfolgsbeispiel hervorgehoben

Successful personalized medicine: Translational research results on pain therapy published in "EbioMedicine"

Chronic pain syndromes such as small fiber neuropathy (SFN) present a challenge, as their treatment remains symptomatic and often unsuccessful. In a "proof of concept" study, which we performed with...

Claudia Trinler and Corinna Rösseler win poster price at Europhysiology in London

Congratulations to Corinna Rösseler and Claudia Trinler who both won a poster prize at the Europhysiology-meeting in September 2018 in London. Corinna Rösseler received a prize for her poster...

Annual Retreat of the Institute of Physiology

Today the Institute of Physiology had for the fourth time its annual retreat – for the third time at Youth Hostel Aachen. Even if the location does not seem to be very fancy (it is better than it...