Veröffentlichungen von Dr. Heidi Noels in den letzten 5 Jahren:

  1. Tilstam, P. V., Soppert, J., Hemmers, C., Harlacher, E., Doring, Y., van der Vorst, E. P. C., Schulte, C., Alampour-Rajabi, S., Theelen, W., Asare, Y., de Winther, M. P. J., Lawrence, T., Bernhagen, J., Schober, A., Zernecke, A., Jankowski, J., Weber, C. & Noels, H. Non-activatable mutant of inhibitor of kappa B kinase alpha (IKKalpha) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice. Atherosclerosis 292, 23-30, doi:10.1016/j.atherosclerosis.2019.10.023 (2020).
  2. Sternkopf, M., Nagy, M., Baaten, C., Kuijpers, M. J. E., Tullemans, B. M. E., Wirth, J., Theelen, W., Mastenbroek, T. G., Lehrke, M., Winnerling, B., Baerts, L., Marx, N., De Meester, I., Doring, Y., Cosemans, J., Daiber, A., Steven, S., Jankowski, J., Heemskerk, J. W. M. & Noels, H. Native, Intact Glucagon-Like Peptide-1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions. Arterioscler Thromb Vasc Biol, ATVBAHA119313645, doi:10.1161/ATVBAHA.119.313645 (2020).
  3. Hermann, J., Noels, H., Theelen, W., Lellig, M., Orth-Alampour, S., Boor, P., Jankowski, V. & Jankowski, J. Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging. Anal Bioanal Chem 412, 1263-1275, doi:10.1007/s00216-019-02296-x (2020).
  4. van der Vorst, E. P. C., Mandl, M., Muller, M., Neideck, C., Jansen, Y., Hristov, M., Gencer, S., Peters, L. J. F., Meiler, S., Feld, M., Geiselhoringer, A. L., de Jong, R. J., Ohnmacht, C., Noels, H., Soehnlein, O., Drechsler, M., Weber, C. & Doring, Y. Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report. Arterioscler Thromb Vasc Biol 39, 685-693, doi:10.1161/ATVBAHA.119.312386 (2019).
  5. Sternkopf, M., Thoroe-Boveleth, S., Beck, T., Oleschko, K., Erlenkotter, A., Tschulena, U., Steppan, S., Speer, T., Goettsch, C., Jankowski, V., Jankowski, J., Noels, H. & European Uremic Toxin Work Group, E. A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients. Toxins (Basel) 11, doi:10.3390/toxins11070389 (2019).
  6. Schick, D., Babendreyer, A., Wozniak, J., Awan, T., Noels, H., Liehn, E., Bartsch, J. W., Vlacil, A. K., Grote, K., Zayat, R., Goetzenich, A., Ludwig, A. & Dreymueller, D. Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans. Atherosclerosis 286, 163-171, doi:10.1016/j.atherosclerosis.2019.03.008 (2019).
  7. Noels, H., Weber, C. & Koenen, R. R. Chemokines as Therapeutic Targets in Cardiovascular Disease. Arterioscler Thromb Vasc Biol 39, 583-592, doi:10.1161/ATVBAHA.118.312037 (2019).
  8. Gajjala, P. R., Bruck, H., Noels, H., Heinze, G., Ceccarelli, F., Kribben, A., Saez-Rodriguez, J., Marx, N., Zidek, W., Jankowski, J. & Jankowski, V. Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach. J Mol Med (Berl) 97, 1451-1463, doi:10.1007/s00109-019-01823-8 (2019).
  9. Schulte, C. & Noels, H. Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway. Acta Physiol (Oxf) 223, e13091, doi:10.1111/apha.13091 (2018).
  10. Schmitz, C., Noels, H., El Bounkari, O., Straussfeld, E., Megens, R. T. A., Sternkopf, M., Alampour-Rajabi, S., Krammer, C., Tilstam, P. V., Gerdes, N., Burger, C., Kapurniotu, A., Bucala, R., Jankowski, J., Weber, C. & Bernhagen, J. Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. FASEB J 32, 4428-4443, doi:10.1096/fj.201800058R (2018).
  11. Noels, H., Theelen, W., Sternkopf, M., Jankowski, V., Moellmann, J., Kraemer, S., Lehrke, M., Marx, N., Martin, L., Marx, G., Jankowski, J., Goetzenich, A. & Stoppe, C. Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery. Sci Rep 8, 11820, doi:10.1038/s41598-018-30235-w (2018).
  12. Noels, H., Boor, P., Goettsch, C., Hohl, M., Jahnen-Dechent, W., Jankowski, V., Kindermann, I., Kramann, R., Lehrke, M., Linz, D., Maack, C., Niemeyer, B., Roma, L. P., Schuett, K., Speer, T., Wagenpfeil, S., Werner, C., Zewinger, S., Bohm, M., Marx, N., Floege, J., Fliser, D. & Jankowski, J. The new SFB/TRR219 Research Centre. Eur Heart J 39, 975-977, doi:10.1093/eurheartj/ehy083 (2018).
  13. Marx, N., Noels, H., Jankowski, J., Floege, J., Fliser, D. & Bohm, M. Mechanisms of cardiovascular complications in chronic kidney disease: research focus of the Transregional Research Consortium SFB TRR219 of the University Hospital Aachen (RWTH) and the Saarland University. Clin Res Cardiol 107, 120-126, doi:10.1007/s00392-018-1260-0 (2018).
  14. Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. & Jankowski, V. Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease. Neurology 91, e1799-e1808, doi:10.1212/WNL.0000000000006457 (2018).
  15. Kehoe, K., Noels, H., Theelen, W., De Hert, E., Xu, S., Verrijken, A., Arnould, T., Fransen, E., Hermans, N., Lambeir, A. M., Venge, P., Van Gaal, L. & De Meester, I. Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects. PLoS One 13, e0197603, doi:10.1371/journal.pone.0197603 (2018).
  16. Domschke, G., Linden, F., Pawig, L., Hafner, A., Akhavanpoor, M., Reymann, J., Doesch, A. O., Erbel, C., Weber, C., Katus, H. A., Noels, H., Erfle, H., Gleissner, C. A. & Runz, H. Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Sci Rep 8, 10516, doi:10.1038/s41598-018-28790-3 (2018).
  17. Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W. & Jankowski, J. Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma. Hypertension 70, 412-419, doi:10.1161/HYPERTENSIONAHA.116.08906 (2017).
  18. Drescher, H. K., Schippers, A., Clahsen, T., Sahin, H., Noels, H., Hornef, M., Wagner, N., Trautwein, C., Streetz, K. L. & Kroy, D. C. beta7-Integrin and MAdCAM-1 play opposing roles during the development of non-alcoholic steatohepatitis. J Hepatol 66, 1251-1264, doi:10.1016/j.jhep.2017.02.001 (2017).
  19. Doring, Y., Noels, H., van der Vorst, E. P. C., Neideck, C., Egea, V., Drechsler, M., Mandl, M., Pawig, L., Jansen, Y., Schroder, K., Bidzhekov, K., Megens, R. T. A., Theelen, W., Klinkhammer, B. M., Boor, P., Schurgers, L., van Gorp, R., Ries, C., Kusters, P. J. H., van der Wal, A., Hackeng, T. M., Gabel, G., Brandes, R. P., Soehnlein, O., Lutgens, E., Vestweber, D., Teupser, D., Holdt, L. M., Rader, D. J., Saleheen, D. & Weber, C. Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies. Circulation 136, 388-403, doi:10.1161/CIRCULATIONAHA.117.027646 (2017).
  20. Asare, Y., Ommer, M., Azombo, F. A., Alampour-Rajabi, S., Sternkopf, M., Sanati, M., Gijbels, M. J., Schmitz, C., Sinitski, D., Tilstam, P. V., Lue, H., Gessner, A., Lange, D., Schmid, J. A., Weber, C., Dichgans, M., Jankowski, J., Pardi, R., de Winther, M. P., Noels, H. & Bernhagen, J. Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proc Natl Acad Sci U S A 114, E2766-E2775, doi:10.1073/pnas.1618411114 (2017).
  21. Noels, H. & Bernhagen, J. Editorial: The CXCR4 Ligand/Receptor Family and the DPP4 Protease in High-Risk Cardiovascular Patients. Front Immunol 7, 58, doi:10.3389/fimmu.2016.00058 (2016).
  22. Pawig, L., Klasen, C., Weber, C., Bernhagen, J. & Noels, H. Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives. Front Immunol 6, 429, doi:10.3389/fimmu.2015.00429 (2015).
  23. Mandl, M., Drechsler, M., Jansen, Y., Neideck, C., Noels, H., Faussner, A., Soehnlein, O., Weber, C. & Doring, Y. Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation. PLoS One 10, e0134176, doi:10.1371/journal.pone.0134176 (2015).
  24. Kuijpers, M. J., Mattheij, N. J., Cipolla, L., van Geffen, J. P., Lawrence, T., Donners, M. M., Boon, L., Lievens, D., Torti, M., Noels, H., Gerdes, N., Cosemans, J. M., Lutgens, E. & Heemskerk, J. W. Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase beta, and Not Via CD40 and IkappaB Kinase alpha. Arterioscler Thromb Vasc Biol 35, 1374-1381, doi:10.1161/ATVBAHA.114.305127 (2015).