Our Publications

A) Original Articles

  • Zinnall U, Weyerer V, Compérat E, Camparo P, Gaisa NT, Knuechel-Clarke R, Perren A, Lugli A, Toma M, Baretton G, Kristiansen G, Wirtz RM, Cheng L, Wullich B, Stoehr R, Hartmann A, Bertz S
    Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization oft he molecular subtype
    Hum Pathol. 2018 Jun 6. pii: S0046-8177(18)30190-4. doi: 10.1016/j.humpath.2018.05.022. IF 3,125
  • Brücken A, Bleilevens C, Berger P, Nolte K, Gaisa NT, Rossaint R, Marx G, Derwall M, Fries M
    Effects of inhaled nitric oxide on outcome after prolonged cardiac arrest in mild therapeutic hypothermia treated rats
    Sci Rep 2018 Apr 30;8(1):6743. doi: 10.1038/s41598-018-25213-1. IF 4,122
  • Reis H, van der Vos KE, Niedworok C, Herold T, Módos O, Szendrői A, Hager T, Ingenwerth M, Vis DJ, Behrendt MA, de Jong J, van der Heijden MS, Peyronnet B, Mathieu R, Wiesweg M, Ablat J, Okon K, Tolkach Y, Keresztes D, Nagy N, Bremmer F, Gaisa NT, Chlosta P, Kriegsmann J, Kovalszky I, Timar J, Kristiansen G, Radzun HJ, Knüchel R, Schuler M, Black P, Rübben H, Hadaschik B, Schmid KW, van Rhijn BWG, Nyirády P, Szarvas T
    Pathogenic and targetable genetic alterations in 70 urachal adenocarcinomas
    Int J Cancer 2018 Apr 19. doi: 10.1002/ijc.31547. IF 7,360
  • Barth I, Schneider U, Grimm T, Karl A, Horst D, Gaisa NT, Knüchel R, Garczyk S
    Progression of urothelial carcinoma in situ oft he urinary bladder: a switch from luminal to basal phenotype and related therapeutic implications
    Virchows Arch 2018 Apr 13. doi: 10.1007/s00428-018-2354-9. IF 2,936
  • Mijnes J, Veeck J, Gaisa NT, Burghardt E, de Ruijter TC, Gostek S, Dahl E, Pfister D, Schmid SC, Knüchel R, Rose M
    Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer
    Clin Epigenetics. 2018 Feb 6;10:15. doi: 10.1186/s13148-018-0447-6. eCollection 2018.
  • Kuhl CK, Keulers A, Strobel K, Schneider H, Gaisa N, Schrading S
    Not all false positive diagnoses are equal: On the prognostic implications of false-positive diagnoses made in breast MRI versus mammography / digital tomosynthesis screening
    Breast Cancer Res. 2018 Feb 9;20(1):13. doi: 10.1186/s13058-018-0937-7.
  • Thiem S, Herold T, Krafft U, Bremmer F, Tolkach Y, Szász AM, Kriegsmann J, Gaisa NT, Niedworok C, Szarvas T, Reis H
    Telomerase reverse transcriptase (TERT) promoter mutations are rare in urachal cancer
    Pathol Int. 2017 Dec;67(12):597-601. doi: 10.1111/pin.12594. Epub 2017 Oct 19.
  • Bremmer F, Behnes CL, Schildhaus HU, Gaisa NT, Reis H, Jarry H, Radzun HJ, Stroebel P, Schweyer S
    The role of beta-catenin mutation and SOX9 expression in sex cord-stromal tumours of the testis
    Virchows Arch. 2017; 470(4):421-428. doi: 10.1007/s00428-017-2090-6. IF 2,848
  • Loosen SH, Schmeding M, Roderburg C, Binnebösel M, Temizel I, Mottaghy FM, Tischendorf JJ, Tacke F, GaisaNT, Hussein K, Lehmann U, Trautwein C, Neumann UP, Luedde T
    A liver nodule in a patient transplanted for primary sclerosing cholangitis: an interdisciplinary diagnostic approach
    Z Gastroenterol 2017; 55(1):56-62. doi: 10.1055/s-0042-111048. IF 1,618
  • Baldia PH, Maurer A, Heide T, Rose M, Stoehr R, Hartmann A, Williams SV, Knowles MA, Knuechel R, GaisaNT
    Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup
    Oncotarget 2016; 7(44):71429-71439. doi: 10.18632/oncotarget.12198. IF 5,168
  • Schlensog M, Magnus L, Heide T, Eschenbruch J, Steib F, Tator M, Kloten V, Rose M, Noetzel E, GaisaNT, Knüchel R, Dahl E
    Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients
    Epigenetics 2016 Sep 13:0. doi: 10.1080/15592294.2016.1229730. [Epub ahead of print] IF 4,394
  • Brücken A, Derwall M, Bleilevens C, Stoppe C, Götzenich A, Gaisa NT, Weis J, Nolte KW, Rossaint R, Ichinose F, Fries M
    Brief inhalation of nitric oxide increases resuscitation success and improves 7-day-survival after cardiac arrest in rats: a randomized controlled animal study
    Crit Care 2015 Nov 17;19:408.doi: 10.1186/s13054-015-1128-x. IF 4,950
  • Broede A, Oll M, Maurer A, Siegert S, Stoerkel S, Golz R,Schwamborn K, Veeck J, Knuechel R, Gaisa NTfor the German study group of bladder cancers
    Differential diagnosis of bladder versus colorectal adenocarcinoma: keratin 7- and GATA3-positivity in nuclear ß-catenin negative glandular tumours define adenocarcinoma of the bladder
    J Clin Pathol 2016; 69(4):307-12. IF 2,687
  • Kroh A, Ulmer FT, Ortiz Brüchle N, Gaisa NT, Klink CD, Neumann UP, Binnebösel M
    Fieber und rezidivierende Koliken nach Cholezystektomie
    Chirurg 2016;87(4):340-3. IF 0,646
  • Molitor M, Junker K, Eltze E, Toma M, Denzinger S, Siegert S, Knuechel R, Gaisa NT
    Comparison of structural genetics of non-schistosoma-associated squamous cell carcinoma of the urinary bladder
    Int J Clin Exp Pathol 2015; 8(7):8143-58. eCollection 2015. IF 1,581
  • Stoehr R, Taubert H, Zinnall U, Giedl J, Gaisa NT, Burger M, Ruemmele P, Hurst CD, Knowles MA, Wullich B, Hartmann A
    Frequency of TERT promoter mutations in prostate cancer
    Pathobiology 2015; 82(2):53-57 IF 1,732
  • Gaisa NT, Wilms H, Wild PJ, Jakse G, Heidenreich A, Knuechel R
    In cystectomy specimens with bladder cancer whole organ embedding increases the detection rate of histopathological parameters, but not of those with prognostic significance
    Virchows Archiv 2015; 466(4):423-432 IF 2,613
  • Bremmer F, Ströbel P, Jarry H, Strecker J, Gaisa N, Strauß A, Schweyer S, Radzun HJ, Behnes CL
    CK19 is a sensitive marker for yolk sac tumours of the testis
    Diagn Pathol 2015; 10:7. doi: 10.1186/s13000-015-0243-y. IF 1,895
  • Geisler C, Gaisa NT, Pfister D, Fuessel S, Kristiansen G, Braunschweig T, Gostek S, Beine B, Diehl HC, Jackson A, Borchers CH, Heidenreich A, Meyer HE, Knüchel R, Henkel C
    Identification and validation of potential new biomarkers for prostate cancer diagnosis and prognosis using 2D-DIGE and MS
    BioMed Research International; Volume 2015, Article ID 454256, doi: 10.1155/2015/454256 IF 2,706
  • Fischbach A, Rogler A, Erber R, Stoehr R, Poulsom R, Heidenreich A, Schneevoigt B-S, Hauke S, Hartmann A, Knuechel R, Veeck J, Gaisa NT
    Fibroblast Growth Factor Receptor (FGFR)amplifications are rare events in bladder cancer
    Histopathology 2015; 66(5):639-649 IF 3,425
  • Rose M, Schubert C, Dierichs L, Gaisa NT, Heer M, Heidenreich A, Knüchel R, Dahl E
    OASIS/CREB3L1 is a novel candidate suppressor gene in human bladder cancer mediating suppression of tumor cell spreading and migration in vitro
    Epigenetics 2014; 9(12):1626-1640 IF 5,108
  • Antony P, Rose M, Heidenreich A, Knüchel R, Gaisa NT*, Dahl E*
    Epigenetic inactivation of ST6GAL1 in human bladder cancer
    BMC Cancer 2014; 14(1):901 doi: 10.1186/1471-2407-14-901. IF 3,319
  • Spiegelberg C, Giedl J, Gaisa NT, Rogler A, Riener MO, Filbeck T, Burger M, Ruemmele P, Hartmann A, Stoehr R
    Frequency of activating mutations in FGFR2 exon 7 in bladder tumors from patients with early-onset and regular-onset disease
    Int J Clin Exp Pathol 2014; 7(4):1708-1713 eCollection 2014. IF 1,783
  • Rose M*, Gaisa NT*, Antony P, Fiedler D, Heidenreich A, Otto W, Denzinger S, Bertz S, Hartmann A, Karl A, Knüchel R, Dahl E
    Epigenetic inactivation of ITIH5 promotes bladder cancer progression and predicts early relapse of pT1 high grade urothelial tumours
    Carcinogenesis 2014; 35(3): 727-736 IF 5,266
  • Stoehr R, Taubert H, Gaisa NT, Kneitz B, Giedl J, Ruemmele P, Wieland WF, Rau TT, Hartmann A
    Lack of evidence for frequent MED12 p.L1224F mutation in prostate tumours from Caucasian patients
    J Pathol 2013; 230(4):453-456 IF 7,330
  • Gaisa NT*, Reinartz A*, Schneider U, Klaus C, Heidenreich A, Jakse G, Kaemmerer E, Klinkhammer BM, Knuechel R, Gassler N
    Levels of acyl-Coenzyme A synthetase 5 in urothelial cells and corresponding neoplasias reflect cellular differentiation
    Histol Histopathol 2013; 28(3):353-364 IF 2,236
  • Oezdemir RF*, Gaisa NT*, Lindemann-Docter K, Gostek S, Weiskirchen R, Ahrens M, Schwamborn K, Stephan C, Pfister D, Heidenreich A, Knuechel R, Henkel C
    Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia
    Clin Biochem 2012; 45(1-2):7-11 IF 2,450
  • Gaisa NT, Graham TA, McDonald SAC, Poulsom R, Heidenreich A, Jakse G, Knüchel R, Wright NA
    Clonal architecture of human prostatic epithelium in benign and malignant conditions
    J Pathol 2011; 225(2):172-180 IF 6,318
  • Gaisa NT, Graham TA, McDonald SAC, Canadillas-Lopez S, Poulsom R, Heidenreich A, Jakse G, Tadrous PJ, Knüchel R, Wright NA
    The human urothelium consists of multiple clonal units, each maintained by a stem cell
    J Pathol 2011; 225(2):163-171 IF 6,318
  • Gaisa NT, Braunschweig T, Reimer N, Bornemann J, Eltze E, Siegert S, Toma M, Villa L, Hartmann A, Knuechel R
    Different immunohistochemical and ultrastructural phenotypes of squamous differentiation in bladder cancer
    Virchows Arch 2011; 458(3):301-312 IF 2,491
  • Koufou S, Lunz JC, Borchardt A, Keck B, Kneitz B, Gaisa NT, Hafner C, Giedl C, Rau TT, Rogler A, Wieland WF, Hartmann A, Stoehr R
    Mutational activation of FGFR3 is not involved in the development of prostate cancer
    Pathobiology 2010; 77(5):249-252 IF 2,291
  • Derwall M, Westerkamp M, Löwer C, Deike-Glindemann J, Schnorrenberger NK, Coburn M, Nolte KW, Gaisa N, Weis J, Siepmann K, Häusler M, Rossaint R, Fries M
    Hydrogen sulphide does not increase resuscitability in a porcrine model of prolonged cardiac arrest
    Shock 2010; 34(2):190-195 IF 3,203
  • Angerer-Shpilenya M, Gaisa NT, Jakse G
    Excision of carcinoma in situ of the glans penis with reconstructive plastic surgery
    Urologe A 2010; 49(3):392-395 IF 0,442
  • Gaisa NT, Klöppel G, Brehmer B, Neulen J, Stephan P, Knüchel R, Donner A
    Virilizing adrenal ganglioneuroma: a rare differential diagnosis in testosterone secreting adrenal tumours
    Pathologe 2009; 30(5):407-410 IF 0,414
  • Gaisa NT, Tilki D, Losen I, Stoehr R, Dahl E, Stief CG, Knüchel R
    Insights from a whole cystectomy specimen – association of primary small cell carcinoma of the urinary bladder with transitional cell carcinoma in situ
    Hum Pathol 2008; 39(8):1258-1262 IF 3,322
  • Gaisa NT*, Köster J*, Reinartz A, Ertmer K, Ehling J, Raupach K, Perez-Bouza A, Knüchel R, Gassler N
    Expression of acyl-CoA synthetase 5 in human epidermis
    Histol Histopathol 2008; 23(4):451-458 IF 2,194
  • Gaisa NT, Donner A, von Serenyi S, Dahl E, Grosse J, Knüchel R
    Urothelial carcinoma in situ of the seminal vesicles – an indicator of tumour multifocality
    Pathologe 2008; 29(5):371-374 IF 0,424

* contributed equally to this work

B) Reviews and Book Chapters

  • Rose M, Gaisa NT
    Immunohistochemical Analysis of Urothelial Carcinoma Tissues for Proliferation and Differentiation Markers
    Methods Mol Biol. 2018;1655:43-52. doi: 10.1007/978-1-4939-7234-0_4.
  • Gaisa NT
    Tumorigenesis from a pathological perspective: Tumor spread and epigenetically regulated genes in bladder cancer
    Pathologe 2016;37(Suppl 2):196-203 IF 0,540
  • Karl A, Grimm T, Jokisch F, Gaisa NT, Stief GC
    Non-muscle invasive bladder cancer: Current aspects of diagnostics, local therapy options and the update of the 2016 WHO classification
    Urologe A 2016;55(9):1247-58 IF 0,331
  • Knüchel-Clarke R, Gaisa NT
    Preneoplastic lesions and precursors of urothelial cancer
    Pathologe 2016;37(1):33-39 IF 0,540
  • Bertz S, Hartmann A, Knüchel-Clarke R, Gaisa NT
    Specific types of bladder cancer
    Pathologe 2016;37(1):40-51 IF 0,540
  • Gaisa NT, Lindemann-Docter K
    Zytologie in der uropathologischen Diagnostik
    Pathologe 2015; 36(6):534-42 IF 0,540
  • Gaisa NT, Knüchel-Clarke R. response letter to “What can be more prognostic than the pTNM category assessed in radical cystectomy samples?” by Sükösd F, Ivanyi B and Pajor L
    Virchows Arch 2015; 467:483-484 IF 2,613
  • Rausch S, Gaisa N, Youssef RF, Lotan Y, Stenzl A, Kälble T
    Squamous cell lesions of the urinary bladder
    Urologe A 2014; 53:368,370-374 IF 0,436
  • Gaisa NT, Lindemann-Docter K
    Non-invasive and invasive urothelial tumours: special challenges in uropathological diagnostics
    Urologe A 2013; 52:949-957 IF 0,436
  • Gaisa NT and Alison MR
    Stem cells, clonal expansion and cancer progression
    J Pathol2012 Virtual Issue Number 2, March; onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291096-9896/homepage/virtual_issues.htm; IF 7,585
  • Lindemann-Docter K, Gaisa NT, Smeets D, Knüchel-Clarke R
    Urine markers with special regard to fluorescent in situ hybridization (FISH)
    Urologe A 2011; 50:297-302 IF 0,497
  • Schwamborn K, Gaisa NT, Henkel C
    Tissue and serum proteomic profiling for diagnostic and prognostic bladder cancer biomarkers
    Expert Rev Proteomics 2010; 7(6):897-906 IF 3,570
  • Antony P, Rose M, Gaisa NT, Alkaya S, Heidenreich A, Knüchel R, Dahl E
    Characterisation of DNA methylation biomarkers for bladder cancer
    Pathologe 2010; 31 Suppl 2:244-250 IF 0,534
  • Knüchel-Clarke R, Dahl E, Gaisa NT, Schwamborn K, Lindemann-Docter K, Henkel C
    Current knowledge in molecular pathology of urothelial cancer
    Pathologe 2010; 31 Suppl 2:234-238 IF 0,534
  • Gaisa NT, Henkel C, Knüchel R
    Tumour node metastasis staging of bladder cancer: prognosis versus pitfalls
    Curr Opin Urol 2010; 20:398-403 IF 2,777
  • Rose M, Gaisa NT
    Immunohistochemical Analysis of Urothelial Carcinoma Tissues for Proliferation and Differentiation Markers.
    Methods Mol Biol 2018; 1655:43-52. doi: 10.1007/978-1-4939-7234-0_4
  • Krieg RC, Gaisa NT, Paweletz CP and Knuechel R
    Proteomic analysis of human bladder tissue using SELDI-approach following microdissection-techniques
    Methods Mol Biol 2005; 293:255-267