LaBooratory of Nephropathology

A) Original articles

2019

Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI.
Mulay SR, Honarpisheh MM, Foresto-Neto O, Shi C, Desai J, Zhao ZB, Marschner JA, Popper B, Buhl EM, Boor P, Linkermann A, Liapis H, Bilyy R, Herrmann M, Romagnani P, Belevich I, Jokitalo E, Becker JU, Anders HJ.
J Am Soc Nephrol. 2019 Oct;30(10):1857-1869. doi: 10.1681/ASN.2018121218. Epub 2019 Jul 11.

Influence of Vitamin C on Antioxidant Capacity of In Vitro Perfused Porcine Kidneys.
Bleilevens C, Doorschodt BM, Fechter T, Grzanna T, Theißen A, Liehn EA, Breuer T, Tolba RH, Rossaint R, Stoppe C, Boor P, Hill A, Fabry G.
Nutrients. 2019 Aug 1;11(8). pii: E1774. doi: 10.3390/nu11081774.

Cold Preflush of Porcine Kidney Grafts Prior to Normothermic Machine Perfusion Aggravates Ischemia Reperfusion Injury.
Fabry G, Doorschodt BM, Grzanna T, Boor P, Elliott A, Stollenwerk A, Tolba RH, Rossaint R, Bleilevens C.
Sci Rep. 2019 Sep 25;9(1):13897. doi: 10.1038/s41598-019-50101-7.

Hypothermic Oxygenated Machine Perfusion of Extended Criteria Kidney Allografts from Brain Dead Donors: Protocol for a Prospective Pilot Study.
Meister FA, Czigany Z, Bednarsch J, Böcker J, Amygdalos I, Morales Santana DA, Rietzler K, Moeller M, Tolba R, Boor P, Rohlfs W, Neumann UP, Lurje G.
JMIR Res Protoc. 2019 Oct 14;8(10):e14622. doi: 10.2196/14622.

Cre recombinase toxicity in podocytes, a novel genetic model for FSGS in adolescent mice.
Frahsek M, Schulte K, Chia-Gil A, Djudjaj S, Schueler H, Leuchtle K, Smeets B, Dijkman H, Floege J, Moeller MJ. 
Am J Physiol Renal Physiol. 2019 Oct 7. doi: 10.1152/ajprenal.00573.2018. [Epub ahead of print]

CNN cascades for segmenting sparse objects in gigapixel whole slide images.
Gadermayr M, Dombrowski AK, Klinkhammer BM, Boor P, Merhof D.
Comput Med Imaging Graph. 2019 Jan;71:40-48. doi: 10.1016/j.compmedimag.2018.11.002. Epub 2018 Nov 16.

Generative Adversarial Networks for Facilitating Stain-Independent Supervised & Unsupervised Segmentation: A Study on Kidney Histology.
Gadermayr M, Gupta L, Appel V, Boor P, Klinkhammer BM, Merhof D.
IEEE Trans Med Imaging. 2019 Feb 14. doi: 10.1109/TMI.2019.2899364. [Epub ahead of print]

Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats.
Klein S, Frohn F, Magdaleno F, Reker-Smit C, Schierwagen R, Schierwagen I, Uschner FE, van Dijk F, Fürst DO, Djudjaj S, Boor P, Poelstra K, Beljaars L, Trebicka J.
Sci Rep. 2019 Feb 19;9(1):2256. doi: 10.1038/s41598-019-38678-5.

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions.
Kuppe C, Leuchtle K, Wagner A, Kabgani N, Saritas T, Puelles VG, Smeets B, Hakroush S, van der Vlag J, Boor P, Schiffer M, Gröne HJ, Fogo A, Floege J, Moeller MJ.
Kidney Int. 2019 Feb 27. pii: S0085-2538(19)30186-3. doi: 10.1016/j.kint.2019.01.037. [Epub ahead of print]

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.
Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LT, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, Dikic I, Brandts C, Iozzo RV, Wygrecka M, Schaefer L.
Kidney Int. 2019 Mar;95(3):540-562. doi: 10.1016/j.kint.2018.10.037. Epub 2019 Jan 31.

Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.
Puelles VG, Fleck D, Ortz L, Papadouri S, Strieder T, Böhner AMC, van der Wolde JW, Vogt M, Saritas T, Kuppe C, Fuss A, Menzel S, Klinkhammer BM, Müller-Newen G, Heymann F, Decker L, Braun F, Kretz O, Huber TB, Susaki EA, Ueda HR, Boor P, Floege J, Kramann R, Kurts C, Bertram JF, Spehr M, Nikolic-Paterson DJ, Moeller MJ.
Kidney Int. 2019 Mar 15. pii: S0085-2538(19)30318-7. doi: 10.1016/j.kint.2019.02.034. [Epub ahead of print]

Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis.
Sun Q, Baues M, Klinkhammer BM, Ehling J, Djudjaj S, Drude NI, Daniel C, Amann K, Kramann R, Kim H, Saez-Rodriguez J, Weiskirchen R, Onthank DC, Botnar RM, Kiessling F, Floege J, Lammers T, Boor P.
Sci Transl Med. 2019 Apr 3;11(486). pii: eaat4865. doi: 10.1126/scitranslmed.aat4865.

Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.
van Roeyen CRC, Martin IV, Drescher A, Schuett KA, Hermert D, Raffetseder U, Otten S, Buhl EM, Braun GS, Kuppe C, Liehn E, Boor P, Weiskirchen R, Eriksson U, Gross O, Eitner F, Floege J, Ostendorf T.
Kidney Int. 2019 May;95(5):1103-1119. doi: 10.1016/j.kint.2018.11.031. Epub 2019 Feb 28.

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.
Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T.
Nat Med. 2019 Jun 3. doi: 10.1038/s41591-019-0462-y. [Epub ahead of print]

2018

The Long Pentraxin PTX3 Is an Endogenous Inhibitor of Hyperoxaluria-Related Nephrocalcinosis and Chronic Kidney Disease.
Marschner JA, Mulay SR, Steiger S, Anguiano L, Zhao Z, Boor P, Rahimi K, Inforzato A, Garlanda C, Mantovani A, Anders HJ.
Front Immunol. 2018 Sep 25;9:2173. doi: 10.3389/fimmu.2018.02173. eCollection 2018.

Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury.
Gross A, Pack LAP, Schacht GM, Kant S, Ungewiss H, Meir M, Schlegel N, Preisinger C, Boor P, Guldiken N, Krusche CA, Sellge G, Trautwein C, Waschke J, Heuser A, Leube RE, Strnad P.
Mucosal Immunol. 2018 Nov;11(6):1630-1639. doi: 10.1038/s41385-018-0062-z. Epub 2018 Aug 16.

Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy.
Moellmann J, Klinkhammer BM, Onstein J, Stöhr R, Jankowski V, Jankowski J, Lebherz C, Tacke F, Marx N, Boor P, Lehrke M.
Diabetes. 2018 Nov;67(11):2410-2419. doi: 10.2337/db17-1212. Epub 2018 Aug 13.

Cellular Origin and Functional Relevance of Collagen I Production in the Kidney.
Buchtler S, Grill A, Hofmarksrichter S, Stöckert P, Schiechl-Brachner G, Rodriguez Gomez M, Neumayer S, Schmidbauer K, Talke Y, Klinkhammer BM, Boor P, Medvinsky A, Renner K, Castrop H, Mack M.
J Am Soc Nephrol. 2018 Jul;29(7):1859-1873. doi: 10.1681/ASN.2018020138. Epub 2018 May 18.

HIF stabilization inhibits renal epithelial cell migration and is associated with cytoskeletal alterations.
Müller S, Djudjaj S, Lange J, Iacovescu M, Goppelt-Struebe M, Boor P.
Sci Rep. 2018 Jun 22;8(1):9497. doi: 10.1038/s41598-018-27918-9.

Oxidative stress in the brain caused by acute kidney injury.
Kovalčíková A, Gyurászová M, Vavrincová-Yaghi D, Vavrinec P, Tóthová Ľ, Boor P, Šebeková K, Celec P.
Metab Brain Dis. 2018 Jun;33(3):961-967. doi: 10.1007/s11011-018-0204-8. Epub 2018 Mar 7.

The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery.
Stoppe C, Averdunk L, Goetzenich A, Soppert J, Marlier A, Kraemer S, Vieten J, Coburn M, Kowark A, Kim BS, Marx G, Rex S, Ochi A, Leng L, Moeckel G, Linkermann A, El Bounkari O, Zarbock A, Bernhagen J, Djudjaj S, Bucala R, Boor P.
Sci Transl Med. 2018 May 16;10(441). pii: eaan4886. doi: 10.1126/scitranslmed.aan4886.

2017 

Urinary endotrophin predicts disease progression in patients with chronic kidney disease.
Rasmussen DGK, Fenton A, Jesky M, Ferro C, Boor P, Tepel M, Karsdal MA, Genovese F, Cockwell P.
Sci Rep. 2017 Dec 11;7(1):17328. doi: 10.1038/s41598-017-17470-3.

Phagocytosis of environmental or metabolic crystalline particles induces cytotoxicity by triggering necroptosis across a broad range of particle size and shape.
Honarpisheh M, Foresto-Neto O, Desai J, Steiger S, Gómez LA, Popper B, Boor P, Anders HJ, Mulay SR.
Sci Rep. 2017 Nov 14;7(1):15523. doi: 10.1038/s41598-017-15804-9.

Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin.
Desai J, Foresto-Neto O, Honarpisheh M, Steiger S, Nakazawa D, Popper B, Buhl EM, Boor P, Mulay SR, Anders HJ.
Sci Rep. 2017 Nov 3;7(1):15003. doi: 10.1038/s41598-017-15106-0.

Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice.
Brylka LJ, Köppert S, Babler A, Kratz B, Denecke B, Yorgan TA, Etich J, Costa IG, Brachvogel B, Boor P, Schinke T, Jahnen-Dechent W.
PLoS One. 2017 Oct 31;12(10):e0187030. doi: 10.1371/journal.pone.0187030. eCollection 2017.

Segmenting renal whole slide images virtually without training data. 
Gadermayr M, Eschweiler D, Jeevanesan A, Klinkhammer BM, Boor P, Merhof D.
Comput Biol Med. 2017 Nov 1;90:88-97. doi: 10.1016/j.compbiomed.2017.09.014. Epub 2017 Sep 23.

Complement C5a receptors C5L2 and C5aR in renal fibrosis. 
Martin IV, Bohner A, Boor P, Shagdarsuren E, Raffetseder U, Lammert F, Floege J, Ostendorf T, Weber SN.
Am J Physiol Renal Physiol. 2017 Sep 13:ajprenal.00060.2017. doi: 10.1152/ajprenal.00060.2017. [Epub ahead of print]

Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. 
Kim-Hellmuth S, Bechheim M, Pütz B, Mohammadi P, Nédélec Y, Giangreco N, Becker J, Kaiser V, Fricker N, Beier E, Boor P, Castel SE, Nöthen MM, Barreiro LB, Pickrell JK, Müller-Myhsok B, Lappalainen T, Schumacher J, Hornung V.
Nat Commun. 2017 Aug 16;8(1):266. doi: 10.1038/s41467-017-00366-1.

Macrophage Migration Inhibitory Factor Limits Renal Inflammation and Fibrosis by Counteracting Tubular Cell Cycle Arrest.
Djudjaj S, Martin IV, Buhl EM, Nothofer NJ, Leng L, Piecychna M, Floege J, Bernhagen J, Bucala R, Boor P.
J Am Soc Nephrol. 2017 Dec;28(12):3590-3604. doi: 10.1681/ASN.2017020190. Epub 2017 Aug 11.

Renal function following xenon anesthesia for partial nephrectomy-An explorative analysis of a randomized controlled study. 
Stevanovic A, Schaefer P, Coburn M, Rossaint R, Stoppe C, Boor P, Pfister D, Heidenreich A, Christ H, Hellmich M, Fahlenkamp AV.
PLoS One. 2017 Jul 18;12(7):e0181022. doi: 10.1371/journal.pone.0181022. eCollection 2017.

YB-1 orchestrates onset and resolution of renal inflammation via IL10 gene regulation.
Wang J, Djudjaj S, Gibbert L, Lennartz V, Breitkopf DM, Rauen T, Hermert D, Martin IV, Boor P, Braun GS, Floege J, Ostendorf T, Raffetseder U.
J Cell Mol Med. 2017 Dec;21(12):3494-3505. doi: 10.1111/jcmm.13260. Epub 2017 Jun 30.

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.
Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig L, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers L, van Gorp R, Ries C, Kusters PJH, van der Wal A, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C.
Circulation. 2017 Jul 25;136(4):388-403. doi: 10.1161/CIRCULATIONAHA.117.027646. Epub 2017 Apr 27.

Murine CD103+ dendritic cells protect against steatosis progression towards steatohepatitis. 
Heier EC, Meier A, Julich-Haertel H, Djudjaj S, Rau M, Tschernig T, Geier A, Boor P, Lammert F, Lukacs-Kornek V. J Hepatol. 2017 Jan 18. pii: S0168-8278(17)30012-0. doi: 10.1016/j.jhep.2017.01.008.

Clot Structure: A Potent Mortality Risk Factor in Patients on Hemodialysis. 
Schuett K, Savvaidis A, Maxeiner S, Lysaja K, Jankowski V, Schirmer SH, Dimkovic N, Boor P, Kaesler N, Dekker FW, Floege J, Marx N, Schlieper G. J Am Soc Nephrol. 2017 Jan 5. pii: ASN.2016030336. doi: 10.1681/ASN.2016030336. [Epub ahead of print]

Regardless of etiology, progressive renal disease causes ultrastructural and functional alterations of peritubular capillaries. 
Bábíčková J, Klinkhammer BM, Buhl EM, Djudjaj S, Hoss M, Heymann F, Tacke F, Floege J, Becker JU, Boor P. Kidney Int. 2017 Jan;91(1):70-85. doi: 10.1016/j.kint.2016.07.038.

2016

Contrast-enhanced CT imaging in patients with chronic kidney disease. 
von Stillfried S, Apitzsch JC, Ehling J, Penzkofer T, Mahnken AH, Knüchel R, Floege J, Boor P. Angiogenesis. 2016 Oct;19(4):525-35. doi: 10.1007/s10456-016-9524-7.

Keratin 23 is a stress-inducible marker of mouse and human ductular reaction in liver disease. 
Guldiken N, Kobazi Ensari G, Lahiri P, Couchy G, Preisinger C, Liedtke C, Zimmermann HW, Ziol M, Boor P, Zucman-Rossi J, Trautwein C, Strnad P. J Hepatol. 2016 Sep;65(3):552-9. doi: 10.1016/j.jhep.2016.04.024.

Comparison of Aerobic Preservation by Venous Systemic Oxygen Persufflation or Oxygenated Machine Perfusion of Warm-Ischemia-Damaged Porcine Kidneys.  
Kalenski J, Mancina E, Paschenda P, Beckers C, Bleilevens C, Tóthová Ľ, Boor P, Gross D, Tolba RH, Doorschodt BM. Eur Surg Res. 2016;57(1-2):10-21. doi: 10.1159/000444851.

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.
Ludwig-Portugall I, Bartok E, Dhana E, Evers BD, Primiano MJ, Hall JP, Franklin BS, Knolle PA, Hornung V, Hartmann G, Boor P, Latz E, Kurts C. Kidney Int. 2016 Sep;90(3):525-39. doi: 10.1016/j.kint.2016.03.035.

CD103+ Kidney Dendritic Cells Protect against Crescentic GN by Maintaining IL-10-Producing Regulatory T Cells.
Evers BD, Engel DR, Böhner AM, Tittel AP, Krause TA, Heuser C, Garbi N, Kastenmüller W, Mack M, Tiegs G, Panzer U, Boor P, Ludwig-Portugall I, Kurts C.
J Am Soc Nephrol. 2016 Apr 1. pii: ASN.2015080873. [Epub ahead of print]

Keratins are novel markers of renal epithelial cell injury.
Djudjaj S, Papasotiriou M, Bülow RD, Wagnerova A, Lindenmeyer MT, Cohen CD, Strnad P, Goumenos DS, Floege J, Boor P.
Kidney Int. 2016 Apr;89(4):792-808. doi: 10.1016/j.kint.2015.10.015. Epub 2016 Feb 6.

The role of PDGF-D in healthy and fibrotic kidneys.
Buhl EM, Djudjaj S, Babickova J, Klinkhammer BM, Folestad E, Borkham-Kamphorst E, Weiskirchen R, Hudkins K, Alpers CE, Eriksson U, Floege J, Boor P.
Kidney Int. 2016 Apr;89(4):848-61. doi: 10.1016/j.kint.2015.12.037. Epub 2016 Feb 18.

2015

Improved preservation of warm ischemia-damaged porcine kidneys after cold storage in Ecosol, a novel preservation solution.
Kalenski J, Mancina E, Paschenda P, Beckers C, Bleilevens C, Tóthová Ľ, Boor P, Doorschodt BM, Tolba RH.
Ann Transplant. 2015 Apr 27;20:233-42. doi: 10.12659/AOT.892823.
Related citations

IL-6 Trans-Signaling Drives Murine Crescentic GN.
Braun GS, Nagayama Y, Maruta Y, Heymann F, van Roeyen CR, Klinkhammer BM, Boor P, Villa L, Salant DJ, Raffetseder U, Rose-John S, Ostendorf T, Floege J.
J Am Soc Nephrol. 2015 Jun 3. pii: ASN.2014111147. [Epub ahead of print]
Related citations

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74.
Djudjaj S, Lue H, Rong S, Papasotiriou M, Klinkhammer BM, Zok S, Klaener O, Braun GS, Lindenmeyer MT, Cohen CD, Bucala R, Tittel AP, Kurts C, Moeller MJ, Floege J, Ostendorf T, Bernhagen J, Boor P.
J Am Soc Nephrol. 2015 Oct 9. pii: ASN.2015020149. [Epub ahead of print]

Quantitative Micro-Computed Tomography Imaging of Vascular Dysfunction in Progressive Kidney Diseases.
Ehling J, Bábíčková J, Gremse F, Klinkhammer BM, Baetke S, Knuechel R, Kiessling F, Floege J, Lammers T, Boor P.
J Am Soc Nephrol. 2015 Jul 20. pii: ASN.2015020204. [Epub ahead of print]
Related citations

Role of Platelet-Derived Growth Factor-CC in Capillary Rarefaction in Renal Fibrosis.
Boor P, Bábíčková J, Steegh F, Hautvast P, Martin IV, Djudjaj S, Nakagawa T, Ehling J, Gremse F, Bücher E, Eriksson U, van Roeyen CR, Eitner F, Lammers T, Floege J, Peutz-Kootstra CJ, Ostendorf T.
Am J Pathol. 2015 Aug;185(8):2132-42. doi: 10.1016/j.ajpath.2015.04.022.
Related citations

Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis.
Schierwagen R, Maybüchen L, Zimmer S, Hittatiya K, Bäck C, Klein S, Uschner FE, Reul W, Boor P, Nickenig G, Strassburg CP, Trautwein C, Plat J, Lütjohann D, Sauerbruch T, Tacke F, Trebicka J.
Sci Rep. 2015 Aug 11;5:12931. doi: 10.1038/srep12931.
Related citations

Turnover of type III collagen reflects disease severity and is associated with progression and microinflammation in patients with IgA nephropathy.
Genovese F, Boor P, Papasotiriou M, Leeming DJ, Karsdal MA, Floege J.
Nephrol Dial Transplant. 2015 Aug 26. pii: gfv301. [Epub ahead of print]
Related citations

Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis.
Kuppe C, Gröne HJ, Ostendorf T, van Kuppevelt TH, Boor P, Floege J, Smeets B, Moeller MJ.
Kidney Int. 2015 Apr 8. doi: 10.1038/ki.2015.116. [Epub ahead of print]
PMID: 25853334
Related citations

Serum and urine markers of collagen degradation reflect renal fibrosis in experimental kidney diseases.
Papasotiriou M, Genovese F, Klinkhammer BM, Kunter U, Nielsen SH, Karsdal MA, Floege J, Boor P.
Nephrol Dial Transplant. 2015 Mar 16. pii: gfv063. [Epub ahead of print]
PMID: 25784725
Related citations

If you lose your nerves, at least you will not get kidney fibrosis!
Boor P, Papasotiriou ME.
Kidney Int. 2015 Feb;87(2):275-7. doi: 10.1038/ki.2014.327.
PMID: 25635720
Related citations

Diffusion-weighted MRI does not reflect kidney fibrosis in a rat model of fibrosis.
Boor P, Perkuhn M, Weibrecht M, Zok S, Martin IV, Gieseke J, Schoth F, Ostendorf T, Kuhl C, Floege J.
J Magn Reson Imaging. 2015 Jan 28. doi: 10.1002/jmri.24853. [Epub ahead of print]
PMID: 25630829
Related citations

Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.
Szabo S, Wögenstein KL, Österreicher CH, Guldiken N, Chen Y, Doler C, Wiche G, Boor P, Haybaeck J, Strnad P, Fuchs P.
J Hepatol. 2015 Jan 21. pii: S0168-8278(15)00012-4. doi: 10.1016/j.jhep.2015.01.007. [Epub ahead of print]
PMID: 25617501 Free Article
Related citations

CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages.
Engel DR, Krause TA, Snelgrove SL, Thiebes S, Hickey MJ, Boor P, Kitching AR, Kurts C.
J Immunol. 2015 Feb 15;194(4):1628-38. doi: 10.4049/jimmunol.1402149. Epub 2015 Jan 16.
PMID: 25595779
Related citations

Determination of the preferred conditions for the isolated perfusion of porcine kidneys.
Mancina E, Kalenski J, Paschenda P, Beckers C, Bleilevens C, Boor P, Doorschodt BM, Tolba RH.
Eur Surg Res. 2015;54(1-2):44-54. doi: 10.1159/000366155. Epub 2014 Oct 21.
PMID: 25341590
Related citations

2014

Gp130 dependent signaling in the podocyte.
Nagayama Y, Braun GS, Jakobs CM, Maruta Y, van Roeyen CR, Klinkhammer BM, Boor P, Villa L, Raffetseder U, Trautwein C, Görtz D, Müller-Newen G, Ostendorf T, Floege J.
Am J Physiol Renal Physiol. 2014 Jun 4. pii: ajprenal.00620.2013. [Epub ahead of print]
PMID: 24899055 [PubMed - as supplied by publisher]
Related citations
Select item 24850012

Comprehensive assessment of nephrotoxicity of intravenously administered sodium-oleate-coated ultrasmall superparamagnetic iron oxide (USPIO) and titanium dioxide (TiO2) nanoparticles in rats
Šebekova K, Dušinska M, Simon Klenovics K, Kollarova R, Kebis A, Staruchova M, Vlkova B, Boor P, Celec P, Hodosy J, Beňo M, Tulinska J, Pribojova J, Bilaničova D, Pojana G, Marcomini A, Volkovova K: . Nanotoxicol 2014, 8:142-57.   
Related citations

Origin of Parietal Podocytes in Atubular Glomeruli Mapped by Lineage Tracing
Schulte K, Berger K, Boor P, Jirak P, Gelman IH, Arkill KP, Neal CR, Kriz W, Floege J, Smeets B, Moeller MJ . J Am Soc Nephrol 2014, 25:129-41.
Related citations

The Regenerative Potential of Parietal Epithelial Cells in Adult Mice
Berger K, Schulte K, Boor P, Kuppe C, van Kuppevelt TH, Floege J, Smeets B, Moeller MJ.. J Am Soc Nephrol. 2014, in print
Related citations 

Mesenchymal stem cells from CKD donors exhibit premature senescence and loss of regenerative potential
Klinkhammer BM, Kramann R, Mallau M, Makowska A, van Roeyen CRC, Rong S, Buecher EB, Boor P, Stuettgen E, Otten S, Floege J, Kunter U: . PLoS ONE 2014, in print
Related citations

Determination of the Preferred Conditions for the Isolated Perfusion of Porcine Kidneys. Mancina E, Kalenski J, Paschenda P, Beckers C, Bleilevens C, Boor P, Doorschodt BM, Tolba RH. Eur Surg Res. 2014 Oct 21;54(1-2):44-54. [Epub ahead of print] PMID: 25341590 [PubMed - as supplied by publisher]
Related citations

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes. Kim S, Becker J, Bechheim M, Kaiser V, Noursadeghi M, Fricker N, Beier E, Klaschik S, Boor P, Hess T, Hofmann A, Holdenrieder S, Wendland JR, Fröhlich H, Hartmann G, Nöthen MM, Müller-Myhsok B, Pütz B, Hornung V, Schumacher J. Nat Commun. 2014 Oct 20;5:5236. doi: 10.1038/ncomms6236. PMID: 25327457 [PubMed - in process]
Related citations

Detection of Activated Parietal Epithelial Cells on the Glomerular Tuft Distinguishes Early Focal Segmental Glomerulosclerosis from Minimal Change Disease. Smeets B, Stucker F, Wetzels J, Brocheriou I, Ronco P, Gröne HJ, D'Agati V, Fogo AB, van Kuppevelt TH, Fischer HP, Boor P, Floege J, Ostendorf T, Moeller MJ. Am J Pathol. 2014 Oct 7. pii: S0002-9440(14)00492-1. doi: 10.1016/j.ajpath.2014.08.007. [Epub ahead of print]
PMID: 25307344 [PubMed - as supplied by publisher]
Related citations

Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules. Wögenstein KL, Szabo S, Lunova M, Wiche G, Haybaeck J, Strnad P, Boor P, Wagner M, Fuchs P.
PLoS One. 2014 Sep 18;9(9):e108323. doi: 10.1371/journal.pone.0108323. eCollection 2014. PMID: 25232867 [PubMed - in process] Free PMC Article
Related citations

Platelet Derived Growth Factors (PDGFs) in Glomerular and Tubulointerstitial Fibrosis. Ostendorf T, Boor P, van Roeyen CRC, Floege J
Kidney Int Suppl 2014, in print
Boor P, Ostendorf T, Floege J: PDGF and the progression of renal disease. Nephrol Dial Transplat 2014, 29 Suppl 1:i45-i54.
Related citations

Genovese F, Manresa AA, Leeming DJ, Karsdal MA, Boor P: The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?
Fibrogenesis Tissue Repair. 2014 Mar 28;7(1):4. doi: 10.1186/1755-1536-7-4. PMID: 24678881 [PubMed] Free PMC Article; Related citations Select item 24667162
Related citations 

2013

Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities. van Roeyen CR, Scurt FG, Brandt S, Kuhl VA, Martinkus S, Djudjaj S, Raffetseder U, Royer HD, Stefanidis I, Dunn SE, Dooley S, Weng H, Fischer T, Lindquist JA, Mertens PR.  Cell Commun Signal. 2013, 11:63. 
Related citations

Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration. Smeets B, Boor P, Dijkman H, Sharma SV, Jirak P, Khera S, Mooren F, Berger K, Bornemann J, Gelman IH, Floege J, van der Vlag J, Wetzels JFM, Moeller MJ:  J Pathol 2013, 229: 645-59. 
Related citations

Platelet-Derived Growth Factor (PDGF)-C neutralization reveals differential roles of PDGF-receptors in liver and renal fibrosis. Martin IV, Borkham-Kamphorst E, Zok S, van Roeyen CRC, Eriksson U, Boor P, Hiththetiya K, Fischer HP, Wasmuth HE, Weiskirchen R, Eitner F, Floege J, Ostendorf T: Am J Pathol 2013, 182: 107-17. 
Related citations

Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms Villa L, Boor P, Konieczny A, Kunter U, van Roeyen CRC, Denecke B, Gan L, Neusser MA and Cohen CD for the ERCB-Consortium, Eitner F, Scholl T, Ostendorf T, Floege J: , J Pathol 2013, 229:672-84. 
Related citations

Biological Responses to PDGF-AA Versus PDGF-CC in Renal Fibroblasts.
Seikrit C, Henkel C, van Roeyen CRC, Bokemeyer D, Eitner F, Martin IV, Boor P, Ruth Knüchel, Meyer HE, Müller-Newen G, Eriksson U, Floege J, Ostendorf T:  Nephrol Dial Transplant 2013, 28:889-900. 
Related citations

Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation. van Roeyen CRC, Zok S, Pruessmeyer J, Boor P, Fleckenstein S, Ostendorf T, Ludwig A, Floege J  Kidney Int 2013, 83: 251-63.
Related citations

Advanced glycation end products in infant formulas do not contribute to insulin resistance associated with their consumption.
Klenovics KS, Boor P, Somoza V, Celec P, Fogliano V, Šebeková K  PLoS ONE 2013, 8:e53056. 
Related citations

Albumin is recycled from the primary urine by tubular transcytosis.
Tenten T, Menzel S, Kunter U, Sicking EM, van Roeyen CVR, Sanden SK, Kaldenbach M, Boor P, Fuss A, Uhlig S, Lanzmich R, Dijkman H, Grepl M, Wild K, Kriz W, Smeets B, Floege J, Moeller MJ:  J Am Soc Nephrol 2013, 24:1966-1980. 
Related citations

Raffetseder U: YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo. Hanssen L, Alidousty C, Djudjaj S, Frye BC, Rauen T, Boor P, Mertens PR, van Roeyen CR, Tacke F, Heymann F, Tittel AP, Koch A, Floege J, Ostendorf T,  J Immunol 2013, J Immunol 2013, 191:2604-2613. 
Related citations

Warfarin Induces Cardiovascular Damage in Mice. Krüger T, Oelenberg S, Kaesler N, Schurgers LJ, van de Sandt A, Boor P, Schlieper GR, Brandenburg VM, Fekete BC, Veulemans V, Ketteler M, Vermeer C, Jahnen-Dechent W, Floege J, Westenfeld R  ATVB 2013, 33:2618-2624.
Related citations

In vivo phage display – A discovery tool in molecular biomedicine.
Bábíčková J, Tóthová Ľ, Boor P, Celec P:  Biotechnol Adv 2013, 31:1247-1259

2012

Behaviour and hormonal status in healthy rats on a diet rich in Maillard reaction products with or without solvent extractable aroma compounds. Sebekova K, Klenovics KS, Boor P, Celec P, Behuliak M, Schieberle P, Heidland A, Palkovits M, Somoza V:  Physiol Behav 2012, 105(3):693-701. 
Related citations

Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin. Kabgani N, Grigoleit T, Schulte K, Sechi A, Sauer-Lehnen S, Tag C, Boor P, Kuppe C, Warsow G, Schordan S, Mostertz J, Chilukoti R, Homuth G, Endlich N, Tacke F, Weiskirchen R, Fuellen G, Endlich K, Floege J, Smeets B, Moeller MJ:  PLoS ONE 2012, 7: e34907. 
Related citations

A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and anti-mesangioproliferative effects. van Roeyen CRC*, Boor P*, Borkham-Kamphorst E, Rong S, Kunter U, Martin IV, Kaitovic A, Fleckenstein S, Perbal B, Weiskirchen R, Ostendorf T, Floege J:  Am J Pathol 2012, 180:1979-1990. 
Related citations

Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury. Djudjaj S, Chatziantoniou C, Raffetseder U, Guerrot D, Dussaule JC, Boor P, Kerroch M, Hanssen L, Brandt S, Dittrich A, Ostendorf T, Floege J, Zhu C, Lindenmeyer M, Cohen CD, Mertens PR:  J Pathol 2012, 228:286-299.
Related citations

Cold shock Y-box protein-1 participates in signaling circuits with auto-regulatory activities. Brandt S, Raffetseder U, Djudjaj S, Schreiter A, Kadereit B, Michele M, Pabst M, Zhu C, Mertens PR.  Eur J Cell Biol. 2012, 91:464-71. 
Related citations

Boor P: EP4 - a new piece in the fibrotic puzzle. Kidney Int 2012, 82:132–135 [editorial]. 
Related citations

The renal (myo-)fibroblast: a heterogenous group of cells.
Boor P, Floege J  Nephrol Dial Transplant 2012, 27:3027–3036.
Related citations

New approaches in progressive kidney diseases. Boor P,  Pathologe 2012, 33:296–301. [German]
Related citations

2011

Notch3 is essential for regulation of the renal vascular tone. Hypertension. Boulos N, Helle F, Dussaule JC, Placier S, Milliez P, Djudjaj S, Guerrot D, Joutel A, Ronco P, Boffa JJ, Chatziantoniou C.  2011, 57:1176-82.    
Related citations

Extracellular YB-1 blockade in experimental nephritis up-regulates Notch-3 receptor expression and signalling. RaffetsederU, Rauen T, Boor P, Ostendorf T, Hanssen L, Floege J, En-Nia A, Djudjaj S, Frye BC, Mertens PR:  Nephron Exp Nephrol 2011, 118:e100-e108. 
Related citations

Effects and mechanisms of angiotensin II receptor blockade with telmisartan in a normotensive model of mesangioproliferative nephritis. Villa L, Boor P, Konieczny A, Kunter U, van Roeyen CRC, Denecke B, Gan L, Kupper MB, Eitner F, Ostendorf T, Floege J  Nephrol Dial Transplant 2011, 26: 3131-43. 
Related citations

Bactofection with Toll-like receptor 4 in a murine model of urinary tract infection. Tóthová Ľ, Hodosy J, Kamodyová N, Janega P, Slobodníková L, Liptáková A, Boor P, Celec P, Curr Microbiol 2011, 62(6):1739-42.  
Related citations

Y-box binding protein-1 mediates profibrotic effects of calcineurin inhibitors in the kidney. Hanssen L, Frye BC, Ostendorf T, Alidousty C, Djudjaj S, Boor P, Rauen T, Floege J, Mertens PR, Raffetseder U,  J Immunol 2011, 187:298-308.Ä
Related citations 

Metabolic syndrome is inversely related to soluble receptor for advanced glycation end products: a study in mother-infant pairs. Klenovicsová K, Boor P, Hrachová J, Furková K, Šebeková K, Biopolym Cell 2011, 27: 132-140. 
Related citations

Peroxisome proliferator-activated receptor-α agonist BAY PP1 attenuates renal fibrosis in rats. Boor P, Celec P, Martin IV, Villa L, Hodosy R, Klenovicsová K, Esposito C, Schäfer S, Albrecht-Küpper B, Ostendorf T, Ostendorf T, Heidland A, Šebeková K,  Kidney Int 2011, 80: 1182–1197. 
Related citations

Induction of Progressive Glomerulonephritis via Podocyte-specific Overexpression of Platelet-derived Growth Factor (PDGF) van Roeyen CRC, Eitner F, Boor P, Moeller MJ, Raffetseder U, Hanssen L, Bücher E, Villa L, Banas M, Hudkins KL, Alpers CE, Ostendorf T, Floege J,  –D. Kidney Int 2011, 80: 1292-1305.
Related citations

Growth Factors in Renal Fibrosis. Boor P, Floege J:  Clin Exp Pharmacol Physiol 2011, 38:391-400. 
Related citations

Renal fibrosis – novel insights into mechanisms and therapeutic targets. Boor P, Ostendorf T, Floege J,  Nat Rev Nephrol 2010; 6:643-656. 
Related citations

Models of IgA nephropathy. Eitner F, Boor P, Floege J  Drug Discov Today Dis Model 2010, 7:21-26.

2010

Association of biochemical parameters and RAGE gene polymorphisms in healthy infants and their mothers. Boor P, Celec P, Klenovicsová K, Vlková B, Szemes T, Minárik G, Turňa J, Šebeková K,  Clin Chim Acta 2010; 411:1034-1040. 
Related citations

PDGF-CC accelerates glomerular capillary repair in experimental glomerulonephritis. Boor P, van Roeyen CRC, Kunter U, Villa L, Bücher E, Hohenstein B, Hugo CP, Eriksson U, Satchell SC, Mathieson PW, Eitner F, Floege J, Ostendorf T:  Am J Pathol 2010; 177:58-69. 
Related citations

2009

Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer. Dahl E, En-Nia A, Wiesmann F, Krings R, Djudjaj S, Breuer E, Fuchs T, Wild PJ, Hartmann A, Dunn SE, Mertens PR.  BMC Cancer. 2009, 9:410. 
Related citations

YB-1 acts as a ligand for Notch-3 receptors and modulates receptor activation. Rauen T, Raffetseder U, Frye BC, Djudjaj S, Mühlenberg PJ, Eitner F, Lendahl U, Bernhagen J, Dooley S, Mertens PR.  J Biol Chem. 2009, 284:26928-40.  
Related citations

Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen. Frye BC, Halfter S, Djudjaj S, Muehlenberg P, Weber S, Raffetseder U, En-Nia A, Knott H, Baron JM, Dooley S, Bernhagen J, Mertens PR.EMBO Rep. 2009, 10:783-9 
Related citations

Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1. Raffetseder U, Rauen T, Djudjaj S, Kretzler M, En-Nia A, Tacke F, Zimmermann HW, Nelson PJ, Frye BC, Floege J, Stefanidis I, Weber C, Mertens PR.  Kidney Int. 2009, 75: 185-96. 
Related citations

Late blockade of the renin-angiotensin system in the obese zucker rat – functional and partial morphological regression of renal injury. Šebeková K, Lill M, Boor P, Heidland A, Amann K,  Am J Nephrol 2009, 29:164-170. 
Related citations

Neuronal activation in the central nervous system during different forms of acute renal failure in rats. Palkovits M, Šebekova K, Gallatz K, Šebekova K Jr, Boor P, Klassen A, Bahner U, Heidland A:  Neuroscience 2009, 159:862-882.
Related citations 

Patients with IgA nephropathy exhibit high systemic PDGF-DD levels. Boor P, Eitner F, Cohen CD, Lindenmeyer MT, for the ERCB-Consortium, Mertens PR, Ostendorf T, Floege J:  Nephrol Dial Transplant 2009; 24:2755-2762. 
Related citations

Renal, vascular and cardiac fibrosis in rats exposed to passive smoking and industrial dust fiber amosite. Boor P, Casper S, Celec P, Beňo M, Hurbánková M, Heidland A, Amann K, Šebeková K. J Cel Mol Med 2009, 13:4484-4491. 
Related citations

Polyclonal IgG ameliorates the course of progressive mesangioproliferative glomerulonephritis in rats. Boor P, Kunter U.  Kidney Blood Pres Res 2009; 32:169-174. 
Related citations

Effects of Regular Moderate Exercise on Early Diabetic nephropathy in Obese Zucker Rats. Boor P, Celec P, Behuliak M, Grančič P, Kebis A, Kukan M, Pronajová N, Liptaj T, Ostendorf T, Šebeková K.  Metabolism 2009; 58:1669-1677. 
Related citations

2008

The selective TP receptor antagonist, S18886 (terutroban), attenuates renal damage in the double transgenic rat model of hypertension. Šebeková K, Ramuscak A, Boor P, Heidland A, Amann K.  Am J Nephrol 2008; 28:47-53. 
Related citations

CCN3 is a novel, endogenous, and PDGF-regulated inhibitor of glomerular cell proliferation. van Roeyen CRC, Eitner F, Scholl T, Boor P, Kunter U, Planque N, Groene HJ, Bleau AM, Perbal B, Ostendorf T, Floege J.  Kidney Int 2008; 73:86-94. 
Related citations

PDGF-C acts as a potent pro-inflammatory cytokine that mediates renal interstitial fibrosis in vivo. Eitner F, Bücher E, van Roeyen C, Kunter U, Song R, Seikrit C, Villa L, Boor P, Bäckström G, Eriksson U, Östman A, Floege J, Ostendorf T. J Am Soc Nephrol 2008; 19:281-289.
Related citations

2007

PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis. BBoor P, Konieczny A, Villa L, Kunter U, van Roeyen CRC, LaRochelle WJ, Smithson G, Arrol S, Ostendorf T, Floege J. Nephrol Dial Translant 2007; 22:1323-31.
Related citations

Complement C5 Mediates Experimental Tubulointerstitial Fibrosis. Boor P, Konieczny A, Villa L, Schult A, Bücher E, Rong S, Kunter U, van Roeyen C.R.C, Polakowski T, Hawlisch H, Hillebrandt S, Lammert F, Eitner F, Floege J, Ostendorf T.  J Am Soc Nephrol 2007; 18:1508-1515. 
Related citations

Mesenchymal Stem Cells Prevent Progressive Experimental Renal Failure but Maldifferentiate into Glomerular Adipocytes. Kunter U, Rong S, Boor P, Eitner F, Müller-Newen G, Djuric Z, van Roeyen CRC, Konieczny A, Ostendorf T, Villa L, Milovanceva-Popovska M, Kerjaschki D, Floege J.  J Am Soc Nephrol 2007; 18:1754-1764. 
Related citations 

The MAP Kinase Erk Regulates Renal Activity of Cyclin Dependent Kinase 2 in Experimental Glomerulonephritis. Bokemeyer D, Panek D, Kitahara M, Trzaskos JM, Müller CE, Hockemeyer J, Kunter U, Boor P, Floege J, Kramer HJ, Ostendorf T:  Nephrol Dial Transplant 2007; 22:3431-3441. 
Related citations

Genomic Damage and Malignancy in End-Stage Renal Failure: Do AGEs Contribute? Šebeková K, Wagner Z, Schupp N, Boor P.  Kidney Blood Press Res 2007; 30:56-66. 
Related citations

The Role of PDGF-D in Mesangioproliferative Glomerulonephritis. Floege J, van Roeyen C, Boor P, Ostendorf T.  Contrib Nephrol 2007; 157:153-158. 
Related citations

Treatment Targets in Renal Fibrosis. Boor P, Sebekova K, Ostendorf T, Floege J.  Nephrol Dial Transplant 2007; 22:3391-407. 
Related citations

Role of T cells and dendritic cells in glomerular immunopathology. Kurts C, Heymann F, Lukacs-Kornek V, Boor P, Floege J.  Semin Immunopathol 2007; 29:317-335.
Related citations
 

B) Review articles

2019

Evolving complexity of MIF signaling.
Jankauskas SS, Wong DWL, Bucala R, Djudjaj S, Boor P.
Cell Signal. 2019 May;57:76-88. doi: 10.1016/j.cellsig.2019.01.006. Epub 2019 Jan 23. Review.

Extracellular Matrix in Kidney Fibrosis: More Than Just a Scaffold.
Bülow RD, Boor P.
J Histochem Cytochem. 2019 May 22:22155419849388. doi: 10.1369/0022155419849388. [Epub ahead of print]

2018

[MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde (German version)].
Boor P.
Pathologe. 2018 Dec;39(Suppl 2):177-184. doi: 10.1007/s00292-018-0535-6. German.

[What is certain in the treatment of glomerulonephritis?]
Floege J, Boor P, Moeller MJ.
Internist (Berl). 2018 Dec;59(12):1268-1278. doi: 10.1007/s00108-018-0500-8. Review. German.

Diffusion-weighted magnetic resonance imaging to assess diffuse renal pathology: a systematic review and statement paper.
Caroli A, Schneider M, Friedli I, Ljimani A, De Seigneux S, Boor P, Gullapudi L, Kazmi I, Mendichovszky IA, Notohamiprodjo M, Selby NM, Thoeny HC, Grenier N, Vallée JP.
Nephrol Dial Transplant. 2018 Sep 1;33(suppl_2):ii29-ii40. doi: 10.1093/ndt/gfy163.

Magnetic resonance imaging T1- and T2-mapping to assess renal structure and function: a systematic review and statement paper.
Wolf M, de Boer A, Sharma K, Boor P, Leiner T, Sunder-Plassmann G, Moser E, Caroli A, Jerome NP.
Nephrol Dial Transplant. 2018 Sep 1;33(suppl_2):ii41-ii50. doi: 10.1093/ndt/gfy198.

Magnetic resonance imaging biomarkers for chronic kidney disease: a position paper from the European Cooperation in Science and Technology Action PARENCHIMA.
Selby NM, Blankestijn PJ, Boor P, Combe C, Eckardt KU, Eikefjord E, Garcia-Fernandez N, Golay X, Gordon I, Grenier N, Hockings PD, Jensen JD, Joles JA, Kalra PA, Krämer BK, Mark PB, Mendichovszky IA, Nikolic O, Odudu A, Ong ACM, Ortiz A, Pruijm M, Remuzzi G, Rørvik J, de Seigneux S, Simms RJ, Slatinska J, Summers P, Taal MW, Thoeny HC, Vallée JP, Wolf M, Caroli A, Sourbron S.
Nephrol Dial Transplant. 2018 Sep 1;33(suppl_2):ii4-ii14. doi: 10.1093/ndt/gfy152.

Cellular and molecular mechanisms of kidney fibrosis.
Djudjaj S, Boor P.
Mol Aspects Med. 2018 Jun 22. pii: S0098-2997(18)30040-2. doi: 10.1016/j.mam.2018.06.002. [Epub ahead of print] Review.

The new SFB/TRR219 Research Centre.
Noels H, Boor P, Goettsch C, Hohl M, Jahnen-Dechent W, Jankowski V, Kindermann I, Kramann R, Lehrke M, Linz D, Maack C, Niemeyer B, Roma LP, Schuett K, Speer T, Wagenpfeil S, Werner C, Zewinger S, Böhm M, Marx N, Floege J, Fliser D, Jankowski J.
Eur Heart J. 2018 Mar 21;39(12):975-977. doi: 10.1093/eurheartj/ehy083. No abstract available.

Cell-free DNA: the role in pathophysiology and as a biomarker in kidney diseases.
Celec P, Vlková B, Lauková L, Bábíčková J, Boor P.
Expert Rev Mol Med. 2018 Jan 18;20:e1. doi: 10.1017/erm.2017.12.

2017

PDGF in organ fibrosis. 
Klinkhammer BM, Floege J, Boor P.
Mol Aspects Med. 2017 Nov 21. pii: S0098-2997(17)30127-9. doi: 10.1016/j.mam.2017.11.008. [Epub ahead of print] Review.

Fibrosis imaging: Current concepts and future directions. 
Baues M, Dasgupta A, Ehling J, Prakash J, Boor P, Tacke F, Kiessling F, Lammers T.
Adv Drug Deliv Rev. 2017 Nov 1;121:9-26. doi: 10.1016/j.addr.2017.10.013. Epub 2017 Nov 20. Review.

Treatment of Renal Fibrosis-Turning Challenges into Opportunities. 
Klinkhammer BM, Goldschmeding R, Floege J, Boor P. Adv Chronic Kidney Dis. 2017 Mar;24(2):117-129. doi: 10.1053/j.ackd.2016.11.002.

2016

Salivary markers of kidney function - Potentials and limitations.
Celec P, Tóthová Ľ, Šebeková K, Podracká Ľ, Boor P.
Clin Chim Acta. 2016 Jan 30;453:28-37. doi: 10.1016/j.cca.2015.11.028. Epub 2015 Nov 26. Review.

Biomarkers: Albuminuria - a marker of systemic microvascular function.
Boor P. Nat Rev Nephrol. 2016 Aug;12(8):449-50. doi: 10.1038/nrneph.2016.82.

2015

Platelet-derived growth factors (PDGFs) in glomerular and tubulointerstitial fibrosis.
Ostendorf T, Boor P, van Roeyen CR, Floege J.
Kidney Int Suppl (2011). 2014 Nov;4(1):65-69. Review.
Related citations

Renal allograft fibrosis: biology and therapeutic targets.
Boor P, Floege J.
Am J Transplant. 2015 Apr;15(4):863-86. doi: 10.1111/ajt.13180. Epub 2015 Feb 17.
PMID: 25691290
Related citations

Keratins in health and disease.
Toivola DM, Boor P, Alam C, Strnad P.
Curr Opin Cell Biol. 2015 Feb;32C:73-81. doi: 10.1016/j.ceb.2014.12.008. Epub 2015 Jan 17. Review.
PMID: 25599598
Related citations
Select item 25595779

2014    

Platelet Derived Growth Factors (PDGFs) in Glomerular and Tubulointerstitial Fibrosis. Ostendorf T, Boor P, van Roeyen CRC, Floege J.  Kidney Int Suppl 2014, in print
Related citations

PDGF and the progression of renal disease. Boor P, Ostendorf T, Floege J:  Nephrol Dial Transplat 2014, 29 Suppl 1:i45-i54.
Related citations 

The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?
Genovese F, Manresa AA, Leeming DJ, Karsdal MA, Boor P. Fibrogenesis Tissue Repair. 2014 Mar 28;7(1):4. doi: 10.1186/1755-1536-7-4. PMID: 24678881 [PubMed] Free PMC Article; Select item 24667162 
Related citations  

2013    

In vivo phage display – A discovery tool in molecular biomedicine. Bábíčková J, Tóthová Ľ, Boor P, Celec P:  Biotechnol Adv 2013, 31:1247-1259
Related citations

2012    

Cold shock Y-box protein-1 participates in signaling circuits with auto-regulatory activities. Brandt S, Raffetseder U, Djudjaj S, Schreiter A, Kadereit B, Michele M, Pabst M, Zhu C, Mertens PR.  Eur J Cell Biol. 2012, 91:464-71. 
Related citations

EP4 - a new piece in the fibrotic puzzle. Boor P.  Kidney Int 2012, 82:132–135 [editorial]. 
Related citations

The renal (myo-)fibroblast: a heterogenous group of cells. Boor P, Floege J:  Nephrol Dial Transplant 2012, 27:3027–3036. 
Related citations

New approaches in progressive kidney diseases. Boor P:  Pathologe 2012, 33:296–301. [German]
Related citations

2011    

Growth Factors in Renal Fibrosis. Boor P, Floege J.  Clin Exp Pharmacol Physiol 2011, 38:391-400. 
Related citations

Renal fibrosis – novel insights into mechanisms and therapeutic targets. Boor P, Ostendorf T, Floege J.  Nat Rev Nephrol 2010; 6:643-656. 
Related citations

Models of IgA nephropathy. Eitner F, Boor P, Floege J:  Drug Discov Today Dis Model 2010, 7:21-26.

2007    

Genomic Damage and Malignancy in End-Stage Renal Failure: Do AGEs Contribute? Šebeková K, Wagner Z, Schupp N, Boor P.  Kidney Blood Press Res 2007; 30:56-66. 
Related citations

The Role of PDGF-D in Mesangioproliferative Glomerulonephritis. Floege J, van Roeyen C, Boor P, Ostendorf T.  Contrib Nephrol 2007; 157:153-158. 
Related citations

Treatment Targets in Renal Fibrosis. Boor P, Sebekova K, Ostendorf T, Floege J.  Nephrol Dial Transplant 2007; 22:3391-407.
Related citations 

Role of T cells and dendritic cells in glomerular immunopathology. Kurts C, Heymann F, Lukacs-Kornek V, Boor P, Floege J. Semin Immunopathol 2007; 29:317-335.
Related citations