Arbeitsgruppe Interventionelle Radiologie

In der Arbeitsgruppe Interventionelle Radiologie werden interdisziplinär am Patientenwohl orientierte Projekte der peripher-vaskulären interventionellen Radiologie sowie -insbesondere- der interventionellen Onkologie bearbeitet. Neben präklinisch-experimentellen Arbeiten führen wir auch klinische Studien durch: 

  • Minimalinvasive (endovaskuläre) Bypassimplantation
  • TIPS
  • Endovascular aortic repair (EVAR)
  • Grundlagenforschung Tumormodell
  • Irreversible Elektroporation
  • Interstitielle Elektrochemotherapie
  • Biopsiesysteme
  • Selektive interne Radiotherapie
  • Pfortaderembolisation
  • Embolisationspartikel
  • Transarterielle Chemotherapie (TACE)
  • Perkutane Behandlung von Osteoidosteomen

Kooperationspartner:

  • Siemens Healthcare AG
  • Helmholtz-Institut für Biomedizinische Technik
  • Sirtex Medical Europe GmbH
  • Fraunhofer MeVis
  • Cook Deutschland GmbH
  • Pharmacept GmbH
  • Surgitaix AG
  • Vygon GmbH & Co. KG
  • Philips Healthcare AG
  • Boston Scientific Medizintechnik GmbH
  • AngioDynamics Inc. Germany

 

Aktuelle Publikationen:

Müller-Franzes G, Nebelung S, Schock J, Haarburger C, Khader F, Pedersoli F, Schulze-Hagen M, Kuhl C, Truhn D
Reliability as a Precondition for Trust-Segmentation Reliability Analysis of Radiomic Features Improves Survival Prediction.
In: Diagnostics (Basel, Switzerland)

Meister FA, Lurje G, Verhoeven S, Wiltberger G, Heij L, Liu WJ, Jiang D, Bruners P, Lang SA, Ulmer TF, Neumann UP, Bednarsch J, Czigany Z
The Role of Sarcopenia and Myosteatosis in Short- and Long-Term Outcomes Following Curative-Intent Surgery for Hepatocellular Carcinoma in a European Cohort.
In: Cancers

Duong F, Gadermayr M, Merhof D, Kuhl C, Bruners P, Loosen SH, Roderburg C, Truhn D, Schulze-Hagen MF
Automated major psoas muscle volumetry in computed tomography using machine learning algorithms.
In: International journal of computer assisted radiology and surgery

Meine TC, Hinrichs JB, Werncke T, Afat S, Biggemann L, Bucher A, Büttner M, Christner S, Dethlefsen E, Engel H, Gerwing M, Getzin T, Gräger S, Gresser E, Grunz JP, Harder F, Heidenreich J, Hitpaß L, Jakobi K, Janisch M, Kocher N, Kopp M, Lennartz S, Martin O, Moher Alsady T, Pamminger M, Pedersoli F, Piechotta PL, Platz Batista da Silva N, Raudner M, Roehrich S, Schindler P, Schwarze V, Seppelt D, Sieren MM, Spurny M, Starekova J, Storz C, Wiesmüller M, Zopfs D, Ringe KI, Meyer BC, Wacker FK

Phantom study for comparison between computed tomography- and C-Arm computed tomography-guided puncture applied by residents in radiology.
In: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Hitpass L, Distelmaier M, Neumann UP, Schöning W, Isfort P, Keil S, Kuhl CK, Bruners P, Barabasch A

Recurrent Colorectal Liver Metastases in the Liver Remnant After Major Liver Surgery-IRE as a Salvage Local Treatment When Resection and Thermal Ablation are Unsuitable.
In: Cardiovascular and interventional radiology

Pedersoli F, Van den Bosch V, Sieben P, Barzakova E, Schulze-Hagen M, Isfort P, Keil S, Wiltberger G, Kuhl CK, Bruners P
Stent Graft Placement by Pseudoaneurysm of the Hepatic Arteries: Efficacy and Patency Rate in Follow-up.
In: Cardiovascular and interventional radiology

Gombert A, Ketting S, Rückbeil MV, Hundertmark AK, Barbati M, Keschenau P, Pedersoli F, Schurink GW, Mees B, Kotelis D, Jacobs MJ
Perioperative and long-term outcome after ascending aortic and arch repair with elephant trunk and open thoracoabdominal aortic aneurysm repair.
In: Journal of vascular surgery

Bednarsch J, Czigany Z, Heij LR, Luedde T, Loosen SH, Dulk MD, Bruners P, Lang SA, Ulmer TF, Neumann UP
The prognostic role of in-hospital transfusion of fresh frozen plasma in patients with cholangiocarcinoma undergoing curative-intent liver surgery.
In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Pedersoli F, Wilkmann C, Penzkofer T, Disselhorst-Klug C, Schmitz-Rode T, Kuhl C, Bruners P, Isfort P
An accelerometer-based guidance device for CT-guided procedures: an improved wireless prototype.
In: Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy

Barzakova E, Senthilvel N, Bruners P, Keil S, Lurje G, Zimmermann M, Kuhl CK, Isfort P
Detectability of Target Lesion During CT-Guided Tumor Ablations: Impact on Ablation Outcome.
In: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

Pedersoli F, Schönau K, Schulze-Hagen M, Keil S, Isfort P, Gombert A, Alizai PH, Kuhl CK, Bruners P, Zimmermann M
Reply to: Letter to the Editor on Endovascular Revascularization with Stent Implantation in Patients with Acute Mesenteric Ischemia Due to Acute Arterial Thrombosis: Clinical Outcome and Predictive Factors.
In: Cardiovascular and interventional radiology

Tietz E, Truhn D, Müller-Franzes G, Berres ML, Hamesch K, Lang SA, Kuhl CK, Bruners P, Schulze-Hagen M
A Radiomics Approach to Predict the Emergence of New Hepatocellular Carcinoma in Computed Tomography for High-Risk Patients with Liver Cirrhosis.
In: Diagnostics (Basel, Switzerland)

Bednarsch J, Czigany Z, Loosen SH, Heij L, Ruckgaber L, Maes H, Krause JP, Reen M, Toteva B, Vosdellen T, Bruners P, Lang SA, Ulmer TF, Roderburg C, Luedde T, Neumann UP
Perioperative rifaximin is not associated with enhanced functional and volumetric recovery after major liver resection.
In: Scientific reports

Schulze-Hagen MF, Roderburg C, Wirtz TH, Jördens MS, Bündgens L, Abu Jhaisha S, Hohlstein P, Brozat JF, Bruners P, Loberg C, Kuhl C, Trautwein C, Tacke F, Luedde T, Loosen SH, Koch A
Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients.
In: Journal of clinical medicine

Heise D, Schulze-Hagen M, Bednarsch J, Eickhoff R, Kroh A, Bruners P, Eickhoff SB, Brecheisen R, Ulmer F, Neumann UP
CT-Based Prediction of Liver Function and Post-PVE Hypertrophy Using an Artificial Neural Network.
In: Journal of clinical medicine

Han T, Nebelung S, Pedersoli F, Zimmermann M, Schulze-Hagen M, Ho M, Haarburger C, Kiessling F, Kuhl C, Schulz V, Truhn D
Advancing diagnostic performance and clinical usability of neural networks via adversarial training and dual batch normalization.
In: Nature communications

Bednarsch J, Czigany Z, Heij LR, Liu D, den Dulk M, Wiltberger G, Bruners P, Ulmer TF, Neumann UP, Lang SA
Compelling Long-Term Results for Liver Resection in Early Cholangiocarcinoma.
In: Journal of clinical medicine

Meister FA, Bednarsch J, Amygdalos I, Boecker J, Strnad P, Bruners P, Lang SA, Ulmer TF, Heij L, Santana DAM, Liu WJ, Lurje G, Neumann UP, Czigany Z
Various myosteatosis selection criteria and their value in the assessment of short- and long-term outcomes following liver transplantation.
In: Scientific reports

Amygdalos I, Bednarsch J, Meister FA, Erren D, Mantas A, Strnad P, Lang SA, Ulmer TF, Boecker J, Liu W, Jiang D, Bruners P, Neumann UP, Czigany Z
Clinical value and limitations of the preoperative C-reactive-protein-to-albumin ratio in predicting post-operative morbidity and mortality after deceased-donor liver transplantation: a retrospective single-centre study.
In: Transplant international : official journal of the European Society for Organ Transplantation

Hitpass L, Amygdalos I, Sieben P, Raaff V, Lang S, Bruners P, Kuhl CK, Barabasch A
MRI-Based Quantitation of Hepatic Steatosis Does Not Predict Hypertrophy Rate after Portal Vein Embolization in Patients with Colorectal Liver Metastasis and Normal to Moderately Elevated Fat Fraction.
In: Journal of clinical medicine

Van den Bosch V, Pedersoli F, Keil S, Neumann UP, Kuhl CK, Bruners P, Zimmermann M
Safety and efficacy of right portal vein embolization in patients with prior left lateral liver resection.
In: Acta radiologica (Stockholm, Sweden : 1987)

Bednarsch J, Czigany Z, Heij LR, Luedde T, Wiltberger G, Dulk MD, Bruners P, Lang SA, Ulmer TF, Neumann UP
The prognostic role of tumor-associated unilateral portal vein occlusion in perihilar cholangiocarcinoma.
In: HPB : the official journal of the International Hepato Pancreato Biliary Association

Pedersoli F, Schönau K, Schulze-Hagen M, Keil S, Isfort P, Gombert A, Alizai PH, Kuhl CK, Bruners P, Zimmermann M
Endovascular Revascularization with Stent Implantation in Patients with Acute Mesenteric Ischemia due to Acute Arterial Thrombosis: Clinical Outcome and Predictive Factors.
In: Cardiovascular and interventional radiology

Wirtz TH, Loosen SH, Schulze-Hagen M, Gorgulho J, Kandler J, Joerdens M, Demir M, Mohr R, Bruners P, Kuhl C, Trautwein C, Berres ML, Tacke F, Luedde T, Roderburg C
Macrophage migration inhibitory factor predicts an unfavorable outcome after transarterial chemoembolization for hepatic malignancies.
In: Clinical and translational science

Sähn MJ, Yüksel C, Keil S, Zeisberger MP, Post M, Kleines M, Brokmann JC, Hübel C, Kuhl CK, Isfort P, Schulze-Hagen MF
Accuracy of Chest CT for Differentiating COVID-19 from COVID-19 Mimics.
In: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

Loosen SH, Schulze-Hagen M, Vucur M, Gorgulho J, Paffenholz P, Benz F, Mohr R, Demir M, Wree A, Kuhl C, Trautwein C, Tacke F, Bruners P, Luedde T, Roderburg C
Elevated soluble urokinase plasminogen activator receptor serum levels indicate poor survival following transarterial chemoembolization therapy for hepatic malignancies: An exploratory analysis.
In: JGH open : an open access journal of gastroenterology and hepatology

Liebl M, Pedersoli F, Zimmermann M, Schulze-Hagen M, Truhn D, Sieben P, von Stillfried S, Tschinaev A, Heinzel A, Kuhl CK, Bruners P, Isfort P
Induction of Contralateral Hepatic Hypertrophy by Unilobar Yttrium-90 Transarterial Radioembolization versus Portal Vein Embolization: An Animal Study.
In: Journal of vascular and interventional radiology : JVIR

Czigany Z, Kramp W, Lurje I, Miller H, Bednarsch J, Lang SA, Ulmer TF, Bruners P, Strnad P, Trautwein C, von Websky MW, Tacke F, Neumann UP, Lurje G
The role of recipient myosteatosis in graft and patient survival after deceased donor liver transplantation.
In: Journal of cachexia, sarcopenia and muscle

Bednarsch J, Czigany Z, Heise D, Joechle K, Luedde T, Heij L, Bruners P, Ulmer TF, Neumann UP, Lang SA
Prognostic evaluation of HCC patients undergoing surgical resection: an analysis of 8 different staging systems.
In: Langenbeck's archives of surgery

Pedersoli F, Hitpass L, Isfort P, Zimmermann M, Schulze-Hagen M, Gombert A, Kuhl CK, Bruners P, Keil S
Recanalization and Stenting of the Celiac and the Superior Mesenteric Artery Supported by Use of a Steerable Introducer Sheath: Report on 2 Years' Experience.
In: Vascular and endovascular surgery

Pedersoli F, Schröder A, Zimmermann M, Schulze-Hagen M, Keil S, Ulmer TF, Neumann UP, Kuhl CK, Bruners P, Isfort P
Percutaneous transhepatic biliary drainage (PTBD) in patients with dilated vs. nondilated bile ducts: technical considerations and complications.
In: European radiology

Bednarsch J, Czigany Z, Lurje I, Amygdalos I, Strnad P, Halm P, Wiltberger G, Ulmer TF, Schulze-Hagen M, Bruners P, Neumann UP, Lurje G
Insufficient future liver remnant and preoperative cholangitis predict perioperative outcome in perihilar cholangiocarcinoma.
In: HPB : the official journal of the International Hepato Pancreato Biliary Association

Bednarsch J, Czigany Z, Lurje I, Trautwein C, Lüdde T, Strnad P, Gaisa NT, Barabasch A, Bruners P, Ulmer T, Lang SA, Neumann UP, Lurje G
Intraoperative Transfusion of Fresh Frozen Plasma Predicts Morbidity Following Partial Liver Resection for Hepatocellular Carcinoma.
In: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

  • Wilkmann C, Ito N, Penzkofer T, Isfort P, Na HS, Hennes M, Disselhorst-Klug C, Mahnken AH, Kuhl CK, Bruners P. A miniature accelerometer-based guidance device for percutaneous computed tomography-guided punctures. Int J Comput Assist Radiol Surg. 2014 Jun 28.
  • Penzkofer T, Slebocki K, Grommes J, Bruners P, Isfort P, Schmitz-Rode T, Langer S, Kuhl CK, Mahnken AH. High-pitch carbon dioxide contrasted CT angiography: pilot study. Cardiovascular and interventional radiology. 2014;37(2):362-70.
  • Cleven NJ, Isfort P, Penzkofer T, Woitok A, Hermanns-Sachweh B, Steinseifer U, Schmitz-Rode T. Wireless Blood Pressure Monitoring with a Novel Implantable Device: Long-Term In Vivo Results. Cardiovascular and interventional radiology. 2014.
  • Penzkofer T*, Isfort P*, Na HS, Wilkmann C, Osterhues S, Besting A, Hanisch C, Bisplinghoff S, Jansing J, von Werder S, Gooding J, de la Fuente M, Mahnken AH, Disselhorst-Klug C, Schmitz-Rode T, Kuhl CK, Bruners P. Technical concepts for vascular electromagnetic navigated interventions: aortic in situ fenestration and transjugular intrahepatic porto-systemic shunts. Biomedizinische Technik Biomedical Engineering. 2014;59(2):153-63. *Authors contributed equally.
  • Isfort P, Witte H, Slabu I, Penzkofer T, Baumann M, Braunschweig T, Kennes LN, Kuhl CK, Schmitz-Rode T, Mahnken AH, Bruners P. Efficacy of Magnetic Thermoablation Using SPIO in the Treatment of Osteoid Osteoma in a Bovine Model Compared to Radiofrequency and Microwave Ablation. Cardiovascular and interventional Radiology. 2014. Epub 2014/01/07.

Bei Fragen bezüglich der Forschungsprojekte oder Doktorarbeiten können Sie uns jederzeit gerne kontaktieren:

Prof. Dr. med. Philipp Bruners
Tel.: 0241 80-89519
pbrunersukaachende

Priv.-Doz. Dr. med. Peter Isfort, MHBA, EBIR
Tel.: 0241 80-89519
isfortukaachende