Promise of THALEA - Overcoming all barriers, even if it is a pandemic like COVID-19 Evolution of THALEA - Creation of European cooperation's 2. Who is behind Thalea THALEA I consortium: Uniklinik RWTH Aachen [...] Since the start of COVID-19, a decrease among ICU staff in Europe is detected even though the workload increases tremendously. This is an unfavourable development, which could lead to a collapse of the [...] Aachen University Hospital in Germany. The system has now been deployed at 18 hospitals across Austria and Germany, where it is already being used to help ICUs treat COVID-19 patients. In light of the pandemic

Das Institut für Physiologie hat die Lehre und Forschung in Physiologie zur Aufgabe. Wir beteiligen uns engagiert am Aachener Modellstudiengang Medizin, in dem bereits in den ersten Semestern eine bessere Verzahnung der vorklinischen und klinischen Elemente angestrebt wird

research data management and aim at improving reusability of data. A contemporary research consortium is obliged to adhere and implement the main FAIR principles: Findability, Accessibility, Interoperability [...] Principles for scientific data management and stewardship. Sci. Data 3, 160018. DOI: 10.1038/sdata.2016.18

Experimentelle Forschungsprojekte der Klinik für Thorax-, Herz- und Gefäßchirurgie.

management. Huong Ly Trinh Huong Ly Trinh is a research assistant. She is majoring in Biotechnology at the FH Aachen – University of Applied Sciences. The focus of her work is the computational modeling of metabolic [...] Engineering at Southeast University in Nanjing (China) and he is now a master student in Biomedical Engineering at RWTH Aachen University. His research is focused on mechanistic modeling of myeloproliferative [...] Trinh is a research assistant working on the computational modeling of cellular interactions and micro-environmental signals in the bone marrow hematopoietic stem cell niches. Bao Hanh Trinh is studying

Her current research is focused on understanding pathological alterations in peripheral nerves. Research © BioRender In neuropathy patients, the excitability of peripheral nerves is altered, and these [...] electrode is placed, and the participants are instructed to press the button when they feel the stimulation. The perception threshold, i.e., when the participants perceive the electrical stimulation, is estimated [...] temperature during the experiments, compared to the human body, is one of the most considerable limitations. Since the cell membrane excitability is highly sensitive to temperature, this limits the conclusions

Zenke M , Lampert A, Beier F, Wagner W . PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation. Clinical Epigenetics (2020) 12: 125. Franzen [...] Pahl HL, Lang F, Kirschner M, Isfort S, Brümmendorf TH , Döhner K, Koschmieder S . Kidney Dysfunction Is Associated with Thrombosis and Disease Severity in Myeloproliferative Neoplasms: Implications from [...] c cells links inflammation and progression of bone marrow fibrosis in MPN. Blood . 2020 Oct 29;136(18):2051-2064. Han Y, Franzen J, Stiehl T, Gobs M, Kuo CC, Nikolic M, Hapala J, Koop BE, Strathmann K

Publikationen im Institut für Pathologie der Uniklinik RWTH Aachen aus der AG Molekulare Onkologie.

Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels . Scientific Reports. (2019) 9:15578. Cypris O., Božić T., Wagner W. Chicken or Egg: Is Clonal Hematopoiesis Primarily Caused [...] division in hematopoietic stem cells - regulation of self-renewal is most essential for efficient repopulation . Stem Cells Dev . (2009) 18(3): 377-385. 2008 Horn P, Bork S, Diehlmann A, Walenda T, Eckstein [...] Schifflers J, Caduc M, Zenke M, Koschmieder S, Wagner W. DNA methylation in primary myelofibrosis is partly associated with driver mutations and distinct from other myeloid malignancies. Clinical Epigenetics

C., Habel, U., Bekrater‐Bodmann, R., & Flor, H. (2025). Temporal Summation of Pain Unpleasantness Is Increased in Borderline Personality Disorder. European Journal of Pain, 29 (6), e70042. Löffler, A [...] dmann, R., Hausner, L., Desch, S., Silvoni, S., ... & Flor, H. (2024). Reduced tactile sensitivity is associated with mild cognitive impairment. EBioMedicine, 99. Bekrater-Bodmann, R., Kehl, I., Giordano [...] online ahead of print. Atanasova K, Lotter T, Bekrater-Bodmann R, Kleindienst N, Reindl W, Lis S (2022). Is it a gut feeling? Bodily sensations associated with the experience of valence and arousal in patients