research project, the synthesis of a liver-like tissue will be optimized and an additional bioreactor for its cultivation will be developed. The liver model will then be connected to the tumor model via a bio
Innovation national und international zu stärken und (inter)national sichtbar zu machen. Gemeinsam mit IT-Experten, Wissenschaftlern und Klinikern wollen wir eine Plattform schaffen, die den Weg in eine neue
strategy for multi-locus diagnostic testing of imprinting disorders Disturbed genomic imprinting and its relevance for human reproduction: causes and clinical consequences
PET-Bildgebung“ Dr. Dion van der Born (Nijmegen, The Netherlands): „Microfluidic flow technology: Can it revolutionize the production of radiopharmaceuticals?“ Von großer Relevanz war auch die Industriea
2 and 3, 2025, which officially introduced the new center and placed interdisciplinary exchange at its core. More than 70 participants, including 19 speakers, two international keynote lecturers, and seven
2 and 3, 2025, which officially introduced the new center and placed interdisciplinary exchange at its core. More than 70 participants, including 19 speakers, two international keynote lecturers, and seven
ahead of print. Atanasova K, Lotter T, Bekrater-Bodmann R, Kleindienst N, Reindl W, Lis S (2022). Is it a gut feeling? Bodily sensations associated with the experience of valence and arousal in patients [...] Bekrater-Bodmann R*, Flor H* (2022). Pleasant touch perception in borderline personality disorder and its relationship with disturbed body representation. Borderline Personal Disord Emot Dysregul 9(1), 3. [...] Conscious Cogn, 88, 103073. Bekrater-Bodmann R (2021). Factors associated with prosthesis embodiment and its importance for prosthetic satisfaction in lower limb amputees. Front Neurorobot 14, 604376. Kleindienst
GTPase 1) will be analyzed in this project, especially its GTPAse activity: How is DRG1 activity affected by the different domains of the protein and by its different interaction partners? The results will [...] domains. This project aims to evaluate how these mutations impact Nup50 interaction with its identified partners and its underlying cellular functions, like nuclear transport or GTP homeostasis. Important methods: [...] M, Lüchtenborg C, Kallas M, Brügger B, Hurt E, Antonin W (2023). Distinct domains in Ndc1 mediate its interaction with the Nup84 complex and the nuclear membrane. Journal of Cell Biology 222(6):e202210059
activity of HOXB4 (i.e. transcriptional activation or repression of its target genes) appears to depend on the cell type itself and its context, the (micro)environment. To gain a better understanding of [...] Funded by the Deutsche Forschungsgemeinschaft (DFG) The homeodomain transcription factor HOXB4 and its impact on early hematopoietic progenitor development To generate multipotent hematopoietic stem- and [...] HOXB4 expression biases hematopoietic differentiation towards myelopoiesis and away from lymphopoiesis, it mediates a `benign´ HSC expansion without leading to leukemia, as observed with other HOX proteins
studies and classical smooth muscle preparations we introduced the PCLS model, refined and extended it during the past 20 years. PCLS are viable lung tissue slices of approximately 250 µm thickness with [...] defined conditions The mechanical forces acting on lung parenchyma during (mechanical) ventilation and its (patho)physiological consequences are currently under intense scrutiny. Several in vivo and cell culture [...] compartments. The receptor tyrosine kinase ephB4 is expressed solely in venous endothelial cells and its ligand ephrinB2 is specific for arterial endothelial cells, smooth muscle cells and their surrounding