foreign professional qualification as equivalent. After your foreign professional qualification has been checked, you will therefore receive a notice of assessment which determines which measures are suitable
significant negative impact on the quality of life and human well-being. Although significant progress has been made in ophthalmology in the past, conditions leading to untreatable blindness in a large number of
of the cell. It is encoded by the CALR gene. The most frequently occurring mutations in CALR have been categorized as type I and type II mutations, wherein type I mutations are characterized by a 52 b [...] wildtype (CALR WT ), 52 bp deletion (CALR DEL52 ) and 5 bp-insertion (CALR INS5 ) variants. It has been shown that the common C‑terminus of mutated CALR is essential for its oncogenic capability [10, 11]
Orthopaedic Trauma of Uniklinik RWTH Aachen is led by Univ.-Prof. Dr. med. Frank Hildebrand who has been recognized for his expertise and care of trauma patients and specifically for his research about new
MARylation is an emerging posttranslational modification (PTM). By regulating proteins and as lately been shown RNA, it likely impacts diverse cellular processes. This modification is intracellularly catalyzed
However, recently the important role of the small airways, i.e. airways < 2 mm diameter in humans, has been realized. Initially, the small airways were addressed by histology, but histology precludes functional [...] l consequences are currently under intense scrutiny. Several in vivo and cell culture models have been developed to study the pulmonary responses to mechanical stretch. While providing extremely useful [...] dilutional coagulopathy. In vitro and in vivo, anti-oxidative and anti-inflammatory properties have been attributed to HES and pro-inflammatory responses up to anaphylactic shock to gelatin. In isolated
to close this gap and help to improve and facilitate upcoming clinical trials in FA. The study has been registered with ClinicalTrials.gov , and provides more information about TRACK-FA and a list of sites
Despite their major function in providing stability and resilience to cells, intermediate filaments have been shown to influence a variety of other cellular processes including the localization and function of [...] Despite their major function in providing stability and resilience to cells, intermediate filaments have been shown to influence a variety of other cellular processes including the localization and function of
patients. Bioactive Adrenomedullin (bio-ADM) is a hormone regulating endothelial function and has been previously validated in over 35.000 patients with diseases where endothelial dysfunction plays a key
mortality. While the association between cardiovascular calcification and cardiovascular events has been established clinically, the molecular mechanisms that control vascular calcification are not well