that had been isolated from the venom of a cone snail, delays desensitization of ASIC3 by stabilizing its open state. In addition, we identify by a combination of functional and computational methods a cavity

Projekte der AG Molekulare Onkologie aus den Institut für Pathologie der Uniklinik RWTH Aachen, Tissue Micro Arrays

d” richtete die Nephrologie der Uniklinik RWTH Aachen gemeinsam mit dem Lehr- und Forschungsgebiet IT-Sicherheit der RWTH Aachen am 22.04.2024 einen Workshop an der Uniklinik Köln aus. Zu den mehr als [...] wurden. Der Workshop fand im Rahmen eines gemeinsamen DFG-geförderten Forschungsprojektes der RWTH (LuFG IT-Sicherheit, Prof. Ulrike Meyer) und der Uniklinik RWTH Aachen (Nephrologie, PD Anja Mühlfeld) statt

increasingly faced with difficult ethical conflicts and dilemmas. In these cases, the CEC offers its help. It serves as a point of contact for employees of the hospital as well as patients and their repr

This honor was not only being bestowed upon Dr. Jahr for his substantial contributions to ORS and its governance, but also for his significant contributions to the field of musculoskeletal research. As

The corresponding IT-project aims at the systematic adoption of techniques and standards of the Social Semantic Web to implement collaborative curriculum mapping for a complete medical model curriculum

n Geräte und Komponenten immer größer werden. Systeme und Softwarelösungen in eine gesamtheitliche IT-Infrastruktur eines Operationssaals bzw. einer Klinik zu integrieren, war und ist das Ziel des „OR

The fruit fly Drosophila melanogaster is an important model organism. It contains an ion channel family, termed PPKs, with homology to ASICs and ENaC in humans. In our last study, which was performed in

deletion (CALR DEL52 ) and 5 bp-insertion (CALR INS5 ) variants. It has been shown that the common C‑terminus of mutated CALR is essential for its oncogenic capability [10, 11]. Furthermore, the CALR MUT C‑terminus [...] IDH2, SRSF2) are frequent. PMF is the least common of the three classic Bcr-Abl negative MPN; however, it is the most aggressive and is associated with a significantly increased morbidity and shortened survival [...] on in the JH2 domain [4]. The basal kinase activity of the JH1 domain of JAK2 is autoinhibited by its JH2 domain in healthy cells [5]. In patients harboring the JAK2V617F mutation, which is defined by

melastatin 2 (TRPM2) cation channel consists of a N-terminal channel domain and a C-terminal enzyme domain. It is activated by the cytosolic enriched second messenger ADP-ribose and is directly linked to oxidative