the spider toxin PcTx1. PcTx1 is a model substance for a drug to modulate ASIC activity. Until now, it was believed that PcTx1 is specific for homomeric ASIC1a. Using the functional and pharmacological

For this reason, the cultivation of anaerobic bacteria is becoming increasingly important again, as it enables research into specific metabolic pathways, microbial and host-microbe interactions and potential

collaboration in both research and teaching underlines the value of international educational networks. It also underlines the successful collaboration between RWTH Aachen University and Maastricht University

cells from chronic pain patients. Thereby, we focus on the voltage-gated sodium channel Nav1.7, as it has been associated with pain. In order to determine that the channel can actually be found on the

behind this extraordinary event was to bring students and teachers together in a completely new way. It was a great opportunity to get to know the people we normally meet in lecture halls and seminar rooms

Laut Schätzungen der WHO leben weltweit rund 254 Millionen Menschen mit Hepatitis B und etwa 50 Millionen mit Hepatitis C. Jährlich kommt es zu ca. 1,2 Millionen Neuinfektionen, wobei rund 1,3 Million

function changes. Therefore, it is not surprising that classical in vitro cell culture does not make it possible to reflect a physiological phenotype of cells. To change this, it is necessary to understand [...] mechanical forces that play a central role in blood vessels and their influence on inflammatory processes. It is our goal to create the basis to develop physiologically relevant in vitro models for vascular i

cycle. We aim understanding how the nucleus reforms at the end of cell division in order to fulfil its manifold functions including DNA replication and transcription. This includes the questions of how [...] mediators. This includes investigations into the role of the endoplasmic reticulum, which is able, via its communication with the cell nucleus, to regulate the amount of cytokines produced in response to cellular

the complex heart-kidney interplay and calls for an increased focus on the cardiorenal patient. Also, it underlines the need of interdisciplinary research, combining the expertise of cardiologists, nephrologists [...] bio-based products and technologies. However, valorisation of research results is often failing, since it requires a direct and interdisciplinary interaction of basic researchers, clinicians and private partners

Why Uniklinik RWTH Aachen? As one of the region’s largest employer, Uniklinik RWTH Aachen offers its staff interesting challenges and a wide variety of opportunities in the booming health market. There