Referent: Prof Dr. Ulrich Sax, Leiter der Arbeitsgruppe „Infrastructure for Translational Research“ am Institut für Medizinische Informatik der Universitätsmedizin Göttingen. Prof. Sax ist eine national [...] Mitarbeiter der Uniklinik RWTH Aachen und der RWTH Aachen University Inhalt: The FAIR Guiding Principles for scientific data management and stewardship [Wilkinson et al 2016] have been designed by different [...] In this talk we present the state of the art using different perspectives, examples and solutions for FAIR data management in Biomedical Informatics. Wilkinson, M.D., Dumontier, M., Aalbersberg, Ij.J.

(AR) can provide intraoperative support for the surgeon by visualizing additional information and have been used in the field of oral and maxillofacial surgery for trauma, tumor, and orthognathic surgery [...] mid-1990s. Computer-assisted surgery (CAS) in the form of navigation has been used for many years now, particularly for reconstruction of the midface. The main problem with previous navigation devices is [...] field of oral and maxillofacial surgery for orthognathic, tumor and trauma surgery. In addition, it can also be used in the context of medical education and training for practicing and planning surgical procedures

med. Frank Hildebrand who has been recognized for his expertise and care of trauma patients and specifically for his research about new treatmenr concepts for severely injured patients. His department is [...] is known for its “Kölsch”, a locally brewed beer, and “Printen”, a sweet type of bread similar to gingerbread. The public transportation system is well organized and regional trains allow for easy day [...] afternoon. The trauma staff is always approachable and available for questions or concerns. As a fellow, there are opportunities open for clinical care and research, including hands-on patient care as well

work on these significant challenges. For example, none of the existing systems considers the degradation of neural connections in the retina or the visual cortex for visual information processing. RTG 2610 [...] field, indicated by their publications in internationally renowned journals, their success in applying for third party funded projects, and their role in the scientific community. Prof. Mokwa and Prof. Walter [...] Vision Conferences 2013, 2015, 2017, and 2019 in Aachen. This conference is a well-known platform for many groups worldwide to present their data to a highly specialized audience and we already hosted

UK Aachen. 2/2021-1/2024 “Paclitaxel-Picelles for Triple-Negative Breast Cancer Therapy” funded by the BMBF (German Science Ministry) with over 2 Mio € for all partners (AG Maurer/223,856€) together with [...] /AG Maurer, total volume of 2,85 Mio €/ 1,17 Mio € for UK RWTH Aachen) 12/2019-11/2022 “Importance of vascular prostate specific membrane antigen for the endogenous radiotherapy of triple-negative breast [...] GADETA Eurostars Grant “Developing tools to assess efficacy and safety of the promising TEG treatment for solid tumors” (E11497 – TEST) Funding by the European Union (1,6000,000€) together with AG Schamel/Minguet

cytoskeleton in the cells which can serves as a mechanical model for muscle filaments. We use fluorescence microscopy and live-cell imaging for our analyses. Selected publications: Bonnin E, Cabochette P, [...] mitosis chromatin decondenses to re-establish the interphase chromatin structure, making it accessible for DNA replication and transcription. On the one hand, molecular mechanisms regulating chromatin condensation [...] built from distinct proteins, termed nucleoporins. Intact nucleocytoplasmic transport is crucial for a healthy cell and genetic mutations in nucleoporins have been linked to many human diseases. We found

The high-affinity receptor for IgE (FcγRI) is crucial for the IgE/antigen-triggered allergic activation of mast cells. This activation follows a so-called bell-shaped dose-response curve with weak induction [...] involved in a negative regulatory signalosome, we used phospho-specific mass spectrometry to screen for proteins showing the same pattern of tyrosine phosphorylation as SHIP1, which is tyrosine-phosphorylated [...] negative regulation of FcγRI signaling and offer possibilities to pinpoint novel target structures for pharmacological intervention.

team. After the initial phase, the staff remains a constant point of contact for further questions that may be bureaucratic or for situations at work that may require mediation. An overview of our main activities: [...] What the integration program team offers The integration team is responsible for application procedures, preparatory processes, support in the first few weeks after arrival and is very familiar with r [...] basic information is provided (knowledge about the German healthcare system and relevant information for integration into our everyday clinical work, training and work shadowing). Great importance is attached

5011, DFG) ERA-PerMed Projekt KidneySign – An integrated multi-omics signature of kidney fibrosis for CKD precision medicine Proteomic prediction and renin angiotensin aldosterone system of early diabetic [...] nephropathy in type 2 DM (EU-FP7-Project) Development, characterization and validation of nanoparticles for the adsorption pf hydrophobic uremic toxins in renal failure-patients (BMBF-IGSCT) Entwicklung eines [...] n des Albumins als Biomarker für kardiovaskuläre Erkrankungen (BMWi) Multifunctional biomaterials for medicine (Helmholtz) Systems biology towards novel chronic kidney diseases and treatment (EU-FP7-Project)

Zielsetzungen der AG Molekulare Onkologie im Institut für Pathologie der Uniklinik RWTH Aachen.